COG0001 glutamate-1-semialdehyde aminotransferase COG0002 N-acetyl-gamma-glutamylphosphate reductase COG0003 anion-transporting ArsA/GET3 family ATPase COG0004 ammonia channel protein AmtB COG0005 purine nucleoside phosphorylase COG0006 Xaa-Pro aminopeptidase COG0007 siroheme synthase COG0008 glutamyl/glutaminyl-tRNA synthetase COG0009 tRNA A37 threonylcarbamoyladenosine synthetase subunit TsaC/SUA5/YrdC COG0010 arginase family enzyme COG0011 uncharacterized protein YqgV (UPF0045/DUF77 family) COG0012 ribosome-binding ATPase YchF (GTP1/OBG family) COG0013 alanyl-tRNA synthetase COG0014 gamma-glutamyl phosphate reductase COG0015 adenylosuccinate lyase COG0016 phenylalanyl-tRNA synthetase alpha subunit COG0017 aspartyl/asparaginyl-tRNA synthetase COG0018 arginyl-tRNA synthetase COG0019 diaminopimelate decarboxylase COG0020 undecaprenyl pyrophosphate synthase COG0021 transketolase COG0022 pyruvate/2-oxoglutarate/acetoin dehydrogenase E1 component COG0023 translation initiation factor 1 (eIF-1/SUI1) COG0024 methionine aminopeptidase COG0025 NhaP-type Na+/H+ or K+/H+ antiporter COG0026 phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) COG0027 formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase) COG0028 thiamine pyrophosphate-dependent acetolactate synthase large subunit-like protein COG0029 aspartate oxidase COG0030 16S rRNA A1518/A1519 N6-dimethyltransferase RsmA/KsgA/DIM1 with predicted DNA glycosylase/AP lyase activity COG0031 cysteine synthase COG0033 phosphoglucomutase COG0034 glutamine phosphoribosylpyrophosphate amidotransferase COG0035 uracil phosphoribosyltransferase COG0036 pentose-5-phosphate-3-epimerase COG0037 tRNA(Ile)-lysidine synthase TilS/MesJ COG0038 H+/Cl- antiporter ClcA COG0039 malate/lactate dehydrogenase COG0040 ATP phosphoribosyltransferase COG0041 phosphoribosylcarboxyaminoimidazole (NCAIR) mutase COG0042 tRNA-dihydrouridine synthase COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase COG0044 dihydroorotase-like cyclic amidohydrolase COG0045 succinyl-CoA synthetase beta subunit COG0046 phosphoribosylformylglycinamidine (FGAM) synthase-like enzyme COG0047 phosphoribosylformylglycinamidine (FGAM) synthase-like amidotransferase family enzyme COG0048 ribosomal protein S12 COG0049 ribosomal protein S7 COG0050 translation elongation factor EF-Tu-like GTPase COG0051 ribosomal protein S10 COG0052 ribosomal protein S2 COG0053 divalent metal cation (Fe/Co/Zn/Cd) transporter COG0054 6,7-dimethyl-8-ribityllumazine synthase COG0055 F0F1-type ATP synthase beta subunit COG0056 F0F1-type ATP synthase alpha subunit COG0057 glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase COG0058 glucan phosphorylase COG0059 ketol-acid reductoisomerase COG0060 isoleucyl-tRNA synthetase COG0061 NAD kinase COG0062 NAD(P)H-hydrate repair Nnr-like enzyme with NAD(P)H-hydrate epimerase domain COG0063 NAD(P)H-hydrate repair Nnr-like enzyme with NAD(P)H-hydrate dehydratase domain COG0064 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase B subunit COG0065 homoaconitase/3-isopropylmalate dehydratase large subunit COG0066 3-isopropylmalate dehydratase small subunit COG0067 glutamate synthase domain-containing protein 1 COG0068 hydrogenase maturation factor HypF (carbamoyltransferase family) COG0069 glutamate synthase domain-containing protein 2 COG0070 glutamate synthase domain-containing protein 3 COG0071 HSP20 family molecular chaperone IbpA COG0072 phenylalanyl-tRNA synthetase beta subunit COG0073 tRNA-binding EMAP/Myf-like protein COG0074 succinyl-CoA synthetase alpha subunit COG0075 aspartate aminotransferase-like enzyme COG0076 glutamate/tyrosine decarboxylase-like PLP-dependent enzyme COG0077 prephenate dehydratase COG0078 ornithine carbamoyltransferase COG0079 histidinol-phosphate/aromatic aminotransferase/cobyric acid decarboxylase-like protein COG0080 ribosomal protein L11 COG0081 ribosomal protein L1 COG0082 chorismate synthase COG0083 homoserine kinase COG0084 Tat protein secretion system quality control protein TatD with DNase activity COG0085 DNA-directed RNA polymerase beta subunit COG0086 DNA-directed RNA polymerase beta' subunit COG0087 ribosomal protein L3 COG0088 ribosomal protein L4 COG0089 ribosomal protein L23 COG0090 ribosomal protein L2 COG0091 ribosomal protein L22 COG0092 ribosomal protein S3 COG0093 ribosomal protein L14 COG0094 ribosomal protein L5 COG0095 lipoate-protein ligase A COG0096 ribosomal protein S8 COG0097 ribosomal protein L6P/L9E COG0098 ribosomal protein S5 COG0099 ribosomal protein S13 COG0100 ribosomal protein S11 COG0101 tRNA U38,U39,U40 pseudouridine synthase TruA COG0102 ribosomal protein L13 COG0103 ribosomal protein S9 COG0104 adenylosuccinate synthase COG0105 nucleoside diphosphate kinase COG0106 phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase COG0107 imidazole glycerol phosphate synthase subunit HisF COG0108 3,4-dihydroxy-2-butanone 4-phosphate synthase COG0109 heme O synthase-like polyprenyltransferase COG0110 acetyltransferase-like isoleucine patch superfamily enzyme COG0111 phosphoglycerate dehydrogenase-like enzyme COG0112 glycine/serine hydroxymethyltransferase COG0113 delta-aminolevulinic acid dehydratase/porphobilinogen synthase COG0114 fumarate hydratase class II COG0115 branched-subunit amino acid aminotransferase/4-amino-4-deoxychorismate lyase COG0116 23S rRNA G2445 N2-methylase RlmL COG0117 pyrimidine deaminase RibD-like protein COG0118 imidazoleglycerol phosphate synthase glutamine amidotransferase subunit HisH COG0119 isopropylmalate/homocitrate/citramalate synthase COG0120 ribose 5-phosphate isomerase COG0121 predicted glutamine amidotransferase COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase COG0123 acetoin utilization deacetylase AcuC-like enzyme COG0124 histidyl-tRNA synthetase COG0125 thymidylate kinase COG0126 3-phosphoglycerate kinase COG0127 inosine/xanthosine triphosphate pyrophosphatase family protein COG0128 5-enolpyruvylshikimate-3-phosphate synthase COG0129 dihydroxyacid dehydratase/phosphogluconate dehydratase COG0130 tRNA U55 pseudouridine synthase TruB COG0131 imidazoleglycerol phosphate dehydratase HisB COG0132 dethiobiotin synthetase COG0133 tryptophan synthase beta subunit COG0134 indole-3-glycerol phosphate synthase COG0135 phosphoribosylanthranilate isomerase COG0136 aspartate-semialdehyde dehydrogenase COG0137 argininosuccinate synthase COG0138 AICAR transformylase/IMP cyclohydrolase PurH COG0139 phosphoribosyl-AMP cyclohydrolase COG0140 phosphoribosyl-ATP pyrophosphohydrolase COG0141 histidinol dehydrogenase COG0142 geranylgeranyl pyrophosphate synthase COG0143 methionyl-tRNA synthetase COG0144 16S rRNA C967 or C1407 C5-methylase (RsmB/RsmF family) COG0145 N-methylhydantoinase A/oxoprolinase/acetone carboxylase beta subunit COG0146 N-methylhydantoinase B/oxoprolinase/acetone carboxylase alpha subunit COG0147 anthranilate/para-aminobenzoate synthase component I COG0148 enolase COG0149 triosephosphate isomerase COG0150 phosphoribosylaminoimidazole (AIR) synthetase COG0151 phosphoribosylamine-glycine ligase COG0152 phosphoribosylaminoimidazole-succinocarboxamide synthase COG0153 galactokinase COG0154 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase A subunit family amidase COG0155 sulfite reductase beta subunit-like hemoprotein COG0156 7-keto-8-aminopelargonate synthetase-like enzyme COG0157 nicotinate-nucleotide pyrophosphorylase COG0158 fructose-1,6-bisphosphatase COG0159 tryptophan synthase alpha subunit COG0160 4-aminobutyrate aminotransferase-like enzyme COG0161 adenosylmethionine-8-amino-7-oxononanoate aminotransferase COG0162 tyrosyl-tRNA synthetase COG0163 3-polyprenyl-4-hydroxybenzoate decarboxylase COG0164 ribonuclease HII COG0165 argininosuccinate lyase COG0166 glucose-6-phosphate isomerase COG0167 dihydroorotate dehydrogenase COG0168 Trk-type K+ transport system membrane component COG0169 shikimate 5-dehydrogenase COG0170 dolichol kinase COG0171 NH3-dependent NAD+ synthetase COG0172 seryl-tRNA synthetase COG0173 aspartyl-tRNA synthetase COG0174 glutamine synthetase COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase COG0176 transaldolase COG0177 endonuclease III COG0178 excinuclease UvrABC ATPase subunit COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase in catechol pathway COG0180 tryptophanyl-tRNA synthetase COG0181 porphobilinogen deaminase COG0182 methylthioribose-1-phosphate isomerase COG0183 acetyl-CoA acetyltransferase COG0184 ribosomal protein S15P/S13E COG0185 ribosomal protein S19 COG0186 ribosomal protein S17 COG0187 DNA gyrase/topoisomerase IV subunit B COG0188 DNA gyrase/topoisomerase IV subunit A COG0189 glutathione synthase/RimK-type ligase-like ATP-grasp enzyme COG0190 5,10-methylene-tetrahydrofolate dehydrogenase/methenyl tetrahydrofolate cyclohydrolase COG0191 fructose/tagatose bisphosphate aldolase COG0192 S-adenosylmethionine synthetase COG0193 peptidyl-tRNA hydrolase COG0194 guanylate kinase COG0195 transcription antitermination factor NusA-like protein COG0196 FAD synthase COG0197 ribosomal protein L16/L10AE COG0198 ribosomal protein L24 COG0199 ribosomal protein S14 COG0200 ribosomal protein L15 COG0201 preprotein translocase subunit SecY COG0202 DNA-directed RNA polymerase alpha subunit COG0203 ribosomal protein L17 COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase COG0205 6-phosphofructokinase COG0206 cell division GTPase FtsZ COG0207 thymidylate synthase COG0208 ribonucleotide reductase beta subunit family protein with ferritin-like domain COG0209 ribonucleotide reductase alpha subunit COG0210 superfamily I DNA/RNA helicase COG0211 ribosomal protein L27 COG0212 5-formyltetrahydrofolate cyclo-ligase COG0213 thymidine phosphorylase COG0214 pyridoxal biosynthesis lyase PdxS COG0215 cysteinyl-tRNA synthetase COG0216 protein subunit release factor A COG0217 transcriptional/translational regulatory protein YebC/TACO1 COG0218 GTP-binding protein EngB required for normal cell division COG0219 tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL COG0220 tRNA G46 methylase TrmB COG0221 inorganic pyrophosphatase COG0222 ribosomal protein L7/L12 COG0223 methionyl-tRNA formyltransferase COG0224 F0F1-type ATP synthase gamma subunit COG0225 peptide methionine sulfoxide reductase MsrA COG0226 ABC-type phosphate transport system substrate-binding protein COG0227 ribosomal protein L28 COG0228 ribosomal protein S16 COG0229 peptide methionine sulfoxide reductase MsrB COG0230 ribosomal protein L34 COG0231 translation elongation factor P/translation initiation factor 5A COG0232 dGTP triphosphohydrolase COG0233 ribosome recycling factor COG0234 co-chaperonin GroES (HSP10) COG0235 ribulose-5-phosphate 4-epimerase/fuculose-1-phosphate aldolase COG0236 acyl carrier protein COG0237 dephospho-CoA kinase COG0238 ribosomal protein S18 COG0239 fluoride ion exporter CrcB/FEX COG0240 glycerol-3-phosphate dehydrogenase COG0241 histidinol phosphatase-like enzyme COG0242 peptide deformylase COG0243 anaerobic selenocysteine-containing dehydrogenase COG0244 ribosomal protein L10 COG0245 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase COG0246 mannitol-1-phosphate/altronate dehydrogenase COG0247 Fe-S oxidoreductase COG0248 exopolyphosphatase/pppGpp-phosphohydrolase COG0249 DNA mismatch repair ATPase MutS COG0250 transcription antitermination factor NusG COG0251 enamine deaminase RidA (YjgF/YER057c/UK114 family) COG0252 L-asparaginase/Glu-tRNA(Gln) amidotransferase subunit D COG0253 diaminopimelate epimerase COG0254 ribosomal protein L31 COG0255 ribosomal protein L29 COG0256 ribosomal protein L18 COG0257 ribosomal protein L36 COG0258 5'-3' exonuclease COG0259 pyridoxine/pyridoxamine 5'-phosphate oxidase COG0260 leucyl aminopeptidase COG0261 ribosomal protein L21 COG0262 dihydrofolate reductase COG0263 glutamate 5-kinase COG0264 translation elongation factor EF-Ts COG0265 S1-C subfamily serine protease COG0266 formamidopyrimidine-DNA glycosylase COG0267 ribosomal protein L33 COG0268 ribosomal protein S20 COG0269 3-keto-L-gulonate-6-phosphate decarboxylase COG0270 site-specific DNA-cytosine methylase COG0271 stress-induced morphogen COG0272 NAD-dependent DNA ligase COG0274 deoxyribose-phosphate aldolase COG0275 16S rRNA C1402 N4-methylase RsmH COG0276 protoheme ferro-lyase COG0277 FAD/FMN-containing dehydrogenase COG0278 glutaredoxin-related protein COG0279 phosphoheptose isomerase COG0280 phosphotransacetylase COG0281 malic enzyme COG0282 acetate kinase COG0283 cytidylate kinase COG0284 orotidine-5'-phosphate decarboxylase COG0285 folylpolyglutamate synthase/dihydropteroate synthase COG0286 type I restriction-modification system DNA methylase subunit COG0287 prephenate dehydrogenase COG0288 carbonic anhydrase COG0289 dihydrodipicolinate reductase COG0290 translation initiation factor IF-3 COG0291 ribosomal protein L35 COG0292 ribosomal protein L20 COG0293 23S rRNA U2552 (ribose-2'-O)-methylase RlmE/FtsJ COG0294 dihydropteroate synthase COG0295 cytidine deaminase COG0296 1,4-alpha-glucan branching enzyme COG0297 glycogen synthase COG0298 hydrogenase maturation factor COG0299 folate-dependent phosphoribosylglycinamide formyltransferase PurN COG0300 short-subunit dehydrogenase COG0301 adenylyl- and sulfurtransferase ThiI COG0302 GTP cyclohydrolase I COG0303 molybdopterin biosynthesis enzyme COG0304 3-oxoacyl-(acyl-carrier-protein) synthase COG0305 replicative DNA helicase COG0306 phosphate/sulfate permease COG0307 riboflavin synthase alpha subunit COG0308 aminopeptidase N COG0309 hydrogenase maturation factor COG0310 ABC-type Co2+ transport system permease subunit COG0311 glutamine amidotransferase PdxT COG0312 predicted Zn-dependent protease COG0313 16S rRNA C1402 (ribose-2'-O) methylase RsmI COG0314 molybdopterin synthase catalytic subunit COG0315 molybdenum cofactor biosynthesis enzyme COG0316 Fe-S cluster assembly iron-binding protein IscA COG0317 (p)ppGpp synthase/HD superfamily hydrolase COG0318 acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II COG0319 ssRNA-specific RNase YbeY (16S rRNA maturation enzyme) COG0320 lipoate synthase COG0321 lipoate-protein ligase B COG0322 excinuclease UvrABC nuclease subunit COG0323 DNA mismatch repair ATPase MutL COG0324 tRNA A37 N6-isopentenylltransferase MiaA COG0325 uncharacterized pyridoxal phosphate-containing UPF0001 family protein COG0326 HSP90 family molecular chaperone COG0327 putative NIF3 family GTP cyclohydrolase 1 type 2 COG0328 ribonuclease HI COG0329 dihydrodipicolinate synthase/N-acetylneuraminate lyase COG0330 regulator of protease activity HflC (stomatin/prohibitin superfamily) COG0331 malonyl CoA-acyl carrier protein transacylase COG0332 3-oxoacyl-[acyl-carrier-protein] synthase III COG0333 ribosomal protein L32 COG0334 glutamate dehydrogenase/leucine dehydrogenase COG0335 ribosomal protein L19 COG0336 tRNA G37 N-methylase TrmD COG0337 3-dehydroquinate synthetase COG0338 site-specific DNA-adenine methylase COG0339 Zn-dependent oligopeptidase COG0340 biotin-(acetyl-CoA carboxylase) ligase COG0341 preprotein translocase subunit SecF COG0342 preprotein translocase subunit SecD COG0343 queuine/archaeosine tRNA-ribosyltransferase COG0344 glycerol-3-phosphate acyltransferase PlsY COG0345 pyrroline-5-carboxylate reductase COG0346 catechol 2,3-dioxygenase-like lactoylglutathione lyase family enzyme COG0347 nitrogen regulatory protein PII COG0348 polyferredoxin COG0349 ribonuclease D COG0350 O6-methylguanine-DNA--protein-cysteine methyltransferase COG0351 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase COG0352 thiamine monophosphate synthase COG0353 recombinational DNA repair protein RecR COG0354 folate-binding Fe-S cluster repair protein YgfZ COG0355 F0F1-type ATP synthase epsilon subunit COG0356 F0F1-type ATP synthase membrane subunit a COG0357 16S rRNA G527 N7-methylase RsmG COG0358 DNA primase COG0359 ribosomal protein L9 COG0360 ribosomal protein S6 COG0361 translation initiation factor IF-1 COG0362 6-phosphogluconate dehydrogenase COG0363 6-phosphogluconolactonase/glucosamine-6-phosphate isomerase/deaminase COG0364 glucose-6-phosphate 1-dehydrogenase COG0365 acyl-coenzyme A synthetase/AMP-(fatty) acid ligase COG0366 glycosidase COG0367 asparagine synthetase B (glutamine-hydrolysing) COG0368 cobalamin synthase COG0369 sulfite reductase alpha subunit-like flavoprotein COG0370 Fe2+ transport system protein B COG0371 glycerol dehydrogenase-like iron-containing ADH family enzyme COG0372 citrate synthase COG0373 glutamyl-tRNA reductase COG0374 Ni,Fe-hydrogenase I large subunit COG0375 Zn finger protein HypA/HybF involved in hydrogenase expression COG0376 catalase (peroxidase I) COG0377 NADH:ubiquinone oxidoreductase subunit B-like Fe-S oxidoreductase COG0378 Ni2+-binding GTPase involved in maturation of urease and hydrogenase COG0379 quinolinate synthase COG0380 trehalose-6-phosphate synthase COG0381 UDP-N-acetylglucosamine 2-epimerase COG0382 4-hydroxybenzoate polyprenyltransferase COG0383 alpha-mannosidase COG0384 predicted PhzF superfamily epimerase YddE/YHI9 COG0385 predicted Na+-dependent transporter COG0386 glutathione peroxidase-family protein COG0387 Ca2+/H+ antiporter COG0388 predicted amidohydrolase COG0389 nucleotidyltransferase/DNA polymerase involved in DNA repair COG0390 ABC-type iron transport system FetAB permease component COG0391 2-phospho-L-lactate transferase/gluconeogenesis factor (CofD/UPF0052 family) COG0392 uncharacterized membrane protein YbhN (UPF0104 family) COG0393 uncharacterized protein YbjQ (UPF0145 family) COG0394 protein-tyrosine-phosphatase COG0395 ABC-type glycerol-3-phosphate transport system permease component COG0396 Fe-S cluster assembly ATPase SufC COG0397 uncharacterized protein YdiU (UPF0061 family) COG0398 uncharacterized membrane protein YdjX (TVP38/TMEM64 family) COG0399 dTDP-4-amino-4,6-dideoxygalactose transaminase COG0400 predicted esterase COG0401 uncharacterized membrane protein YqaE (UPF0057 family) COG0402 cytosine/adenosine deaminase-related metal-dependent hydrolase COG0403 glycine cleavage system pyridoxal-binding protein P COG0404 glycine cleavage system aminomethyltransferase T COG0405 gamma-glutamyltranspeptidase COG0406 broad specificity phosphatase PhoE COG0407 uroporphyrinogen-III decarboxylase COG0408 coproporphyrinogen III oxidase COG0409 hydrogenase maturation factor COG0410 ABC-type branched-subunit amino acid transport system ATPase component COG0411 ABC-type branched-subunit amino acid transport system ATPase component COG0412 dienelactone hydrolase COG0413 ketopantoate hydroxymethyltransferase COG0414 pantothenate synthetase COG0415 deoxyribodipyrimidine photolyase COG0416 fatty acid/phospholipid biosynthesis enzyme COG0417 DNA polymerase elongation subunit (family B) COG0418 dihydroorotase COG0419 DNA repair exonuclease SbcCD ATPase subunit COG0420 DNA repair exonuclease SbcCD nuclease subunit COG0421 spermidine synthase COG0422 thiamine biosynthesis protein ThiC COG0423 glycyl-tRNA synthetase (class II) COG0424 predicted house-cleaning NTP pyrophosphatase (Maf/HAM1 superfamily) COG0425 TusA-related sulfurtransferase COG0426 flavorubredoxin COG0427 acyl-CoA hydrolase COG0428 zinc transporter ZupT COG0429 predicted alpha/beta-fold hydrolase COG0430 RNA 3'-terminal phosphate cyclase COG0431 NAD(P)H-dependent FMN reductase COG0432 thiamine phosphate synthase YjbQ (UPF0047 family) COG0433 DNA helicase HerA-like ATPase COG0434 predicted TIM-barrel enzyme COG0435 glutathionyl-hydroquinone reductase COG0436 aspartate/methionine/tyrosine aminotransferase COG0437 Fe-S-cluster-containing dehydrogenase component COG0438 glycosyltransferase involved in cell wall biosynthesis COG0439 biotin carboxylase COG0440 acetolactate synthase small subunit COG0441 threonyl-tRNA synthetase COG0442 prolyl-tRNA synthetase COG0443 molecular chaperone DnaK (HSP70) COG0444 ABC-type dipeptide/oligopeptide/nickel transport system ATPase component COG0445 tRNA U34 5-carboxymethylaminomethyl modifying enzyme MnmG/GidA COG0446 NADPH-dependent 2,4-dienoyl-CoA reductase/sulfur reductase-like enzyme COG0447 1,4-dihydroxy-2-naphthoyl-CoA synthase COG0448 ADP-glucose pyrophosphorylase COG0449 glucosamine 6-phosphate synthetase-like amidotransferase/phosphosugar isomerase protein COG0450 alkyl hydroperoxide reductase subunit AhpC COG0451 nucleoside-diphosphate-sugar epimerase COG0452 phosphopantothenoylcysteine synthetase/decarboxylase COG0454 GNAT superfamily N-acetyltransferase COG0455 MinD-like ATPase involved in chromosome partitioning or flagellar assembly COG0456 ribosomal protein S18 acetylase RimI-like enzyme COG0457 tetratricopeptide (TPR) repeat protein COG0458 carbamoylphosphate synthase large subunit COG0459 chaperonin GroEL (HSP60 family) COG0460 homoserine dehydrogenase COG0461 orotate phosphoribosyltransferase COG0462 phosphoribosylpyrophosphate synthetase COG0463 glycosyltransferase involved in cell wall biosynthesis COG0464 SpoVK/Ycf46/Vps4 family AAA+-type ATPase COG0465 ATP-dependent Zn protease COG0466 ATP-dependent Lon protease COG0467 KaiC/GvpD/RAD55 family RecA-like ATPase COG0468 RecA/RadA recombinase COG0469 pyruvate kinase COG0470 DNA polymerase III delta prime subunit COG0471 di/tricarboxylate transporter COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase COG0473 isocitrate/isopropylmalate dehydrogenase COG0474 magnesium-transporting ATPase (P-type) COG0475 Kef-type K+ transport system membrane component KefB COG0476 molybdopterin/thiamine biosynthesis adenylyltransferase COG0477 MFS family permease COG0478 RIO-like serine/threonine protein kinase COG0479 succinate dehydrogenase/fumarate reductase-like Fe-S protein COG0480 translation elongation factor EF-G COG0481 translation elongation factor EF-4 COG0482 tRNA U34 2-thiouridine synthase MnmA/TrmU COG0483 fructose-1,6-bisphosphatase/inositol monophosphatase family enzyme COG0484 DnaJ-class molecular chaperone COG0486 tRNA U34 5-carboxymethylaminomethyl modifying GTPase MnmE/TrmE COG0488 ATPase subunit of ABC transporter with duplicated ATPase domains COG0489 Mrp family chromosome partitioning ATPase COG0490 K+/H+ antiporter YhaU regulatory subunit KhtT COG0491 glyoxylase-like metal-dependent hydrolase (beta-lactamase superfamily II) COG0492 thioredoxin reductase COG0493 NADPH-dependent glutamate synthase beta subunit-like oxidoreductase COG0494 8-oxo-dGTP pyrophosphatase MutT (NUDIX family) COG0495 leucyl-tRNA synthetase COG0496 broad specificity polyphosphatase/5'/3'-nucleotidase SurE COG0497 DNA repair ATPase RecN COG0498 threonine synthase COG0499 S-adenosylhomocysteine hydrolase COG0500 SAM-dependent methyltransferase COG0501 Zn-dependent protease with chaperone function COG0502 biotin synthase-like enzyme COG0503 adenine/guanine phosphoribosyltransferase-like PRPP-binding protein COG0504 CTP synthase (UTP-ammonia lyase) COG0505 carbamoylphosphate synthase small subunit COG0506 proline dehydrogenase COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit COG0508 pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) component COG0509 glycine cleavage system H lipoate-binding protein COG0510 thiamine kinase-like enzyme COG0511 biotin carboxyl carrier protein COG0512 anthranilate/para-aminobenzoate synthase component II COG0513 superfamily II DNA/RNA helicase COG0514 superfamily II DNA helicase RecQ COG0515 serine/threonine protein kinase COG0516 IMP dehydrogenase/GMP reductase COG0517 CBS domain-containing protein COG0518 GMP synthase-like glutamine amidotransferase COG0519 GMP synthase PP-ATPase subunit COG0520 selenocysteine lyase/cysteine desulfurase COG0521 molybdopterin biosynthesis enzyme MoaB COG0522 ribosomal protein S4 COG0523 G3E family GTPase COG0524 sugar/nucleoside kinase (ribokinase family) COG0525 valyl-tRNA synthetase COG0526 thiol-disulfide isomerase/thioredoxin COG0527 aspartokinase COG0528 uridylate kinase COG0529 adenylylsulfate kinase-like enzyme COG0530 Ca2+/Na+ antiporter COG0531 amino acid transporter COG0532 translation initiation factor IF-2 COG0533 tRNA A37 threonylcarbamoyltransferase TsaD COG0534 Na+-driven multidrug efflux pump COG0535 MoaA/NifB/PqqE/SkfB family radical SAM enzyme COG0536 GTPase involved in cell partitioning and DNA repair COG0537 diadenosine tetraphosphate (Ap4A) HIT family hydrolase COG0538 isocitrate dehydrogenase COG0539 ribosomal protein S1 COG0540 aspartate carbamoyltransferase catalytic subunit COG0541 signal recognition particle GTPase COG0542 ATP-dependent Clp protease ATP-binding subunit ClpA COG0543 NAD(P)H-flavin reductase COG0544 FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) COG0545 FKBP-type peptidyl-prolyl cis-trans isomerase COG0546 phosphoglycolate phosphatase-like HAD superfamily hydrolase COG0547 anthranilate phosphoribosyltransferase COG0548 acetylglutamate kinase COG0549 carbamate kinase COG0550 DNA topoisomerase IA COG0551 ssDNA-binding Zn-finger/Zn-ribbon topoisomerase 1 COG0552 signal recognition particle GTPase COG0553 SNF2 family DNA or RNA helicase COG0554 glycerol kinase COG0555 ABC-type sulfate transport system permease component COG0556 excinuclease UvrABC helicase subunit UvrB COG0557 exoribonuclease R COG0558 phosphatidylglycerophosphate synthase COG0559 branched-subunit amino acid ABC-type transport system permease component COG0560 phosphoserine phosphatase COG0561 hydroxymethylpyrimidine pyrophosphatase-like HAD family hydrolase COG0562 UDP-galactopyranose mutase COG0563 adenylate kinase family enzyme COG0564 23S rRNA-/tRNA-specific pseudouridylate synthase COG0565 tRNA C32,U32 (ribose-2'-O)-methylase TrmJ COG0566 tRNA G18 (ribose-2'-O)-methylase SpoU COG0567 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component-like enzyme COG0568 DNA-directed RNA polymerase sigma subunit (sigma70/sigma32) COG0569 Trk K+ transport system NAD-binding subunit COG0571 dsRNA-specific ribonuclease COG0572 uridine kinase COG0573 ABC-type phosphate transport system permease subunit COG0574 phosphoenolpyruvate synthase/pyruvate phosphate dikinase COG0575 CDP-diglyceride synthetase COG0576 molecular chaperone GrpE (heat shock protein) COG0577 ABC-type antimicrobial peptide transport system permease subunit COG0578 glycerol-3-phosphate dehydrogenase COG0579 L-2-hydroxyglutarate oxidase LhgO COG0580 glycerol uptake facilitator-like aquaporin COG0581 ABC-type phosphate transport system permease subunit COG0582 integrase COG0583 DNA-binding transcriptional LysR family regulator COG0584 glycerophosphoryl diester phosphodiesterase COG0585 tRNA(Glu) U13 pseudouridine synthase TruD COG0586 membrane protein DedA with SNARE-associated domain COG0587 DNA polymerase III alpha subunit COG0588 bisphosphoglycerate-dependent phosphoglycerate mutase COG0589 nucleotide-binding universal stress UspA family protein COG0590 tRNA(Arg) A34 adenosine deaminase TadA COG0591 Na+/proline symporter COG0592 DNA polymerase III sliding clamp (beta) subunit (PCNA family) COG0593 chromosomal replication initiation ATPase DnaA COG0594 RNase P protein component COG0595 mRNA degradation ribonuclease J1/J2 COG0596 pimeloyl-ACP methyl ester carboxylesterase COG0597 lipoprotein signal peptidase COG0598 Mg2+ and Co2+ transporter CorA COG0599 alkylhydroperoxidase/carboxymuconolactone decarboxylase family protein YurZ COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system permease component COG0601 ABC-type dipeptide/oligopeptide/nickel transport system permease component COG0602 organic radical activating enzyme COG0603 7-cyano-7-deazaguanine synthase in queuosine biosynthesis COG0604 NADPH:quinone reductase-like Zn-dependent oxidoreductase COG0605 superoxide dismutase COG0606 predicted ATPase with chaperone activity COG0607 rhodanese-related sulfurtransferase COG0608 single-stranded DNA-specific DHH superfamily exonuclease COG0609 ABC-type Fe3+-siderophore transport system permease subunit COG0610 type I site-specific restriction-modification system R (restriction) subunit COG0611 thiamine monophosphate kinase COG0612 predicted Zn-dependent peptidase COG0613 predicted metal-dependent phosphoesterase TrpH COG0614 ABC-type Fe3+-hydroxamate transport system substrate-binding protein COG0615 glycerol-3-phosphate cytidylyltransferase-like family protein COG0616 ClpP class serine protease COG0617 tRNA nucleotidyltransferase/poly(A) polymerase COG0618 nanoRNase/pAp phosphatase (c-di-AMP/oligoRNAs hydrolase) COG0619 energy-coupling factor transporter transmembrane protein EcfT COG0620 methionine synthase II (cobalamin-independent) COG0621 tRNA A37 methylthiotransferase MiaB COG0622 predicted phosphodiesterase COG0623 enoyl-[acyl-carrier-protein] reductase (NADH) COG0624 acetylornithine deacetylase/succinyl-diaminopimelate desuccinylase-like protein COG0625 glutathione S-transferase COG0626 cystathionine beta-lyase/cystathionine gamma-synthase COG0627 S-formylglutathione hydrolase FrmB COG0628 predicted PurR-regulated permease PerM COG0629 single-stranded DNA-binding protein COG0630 type IV secretory pathway ATPase VirB11/archaellum biosynthesis ATPase COG0631 serine/threonine protein phosphatase PrpC COG0632 Holliday junction resolvasome RuvABC DNA-binding subunit COG0633 ferredoxin COG0634 hypoxanthine-guanine phosphoribosyltransferase COG0635 coproporphyrinogen III oxidase-like Fe-S oxidoreductase COG0636 F0F1-type ATP synthase membrane subunit c/vacuolar-type H+-ATPase subunit K COG0637 beta-phosphoglucomutase-like phosphatase (HAD superfamily) COG0638 20S proteasome alpha/beta subunit COG0639 diadenosine tetraphosphatase ApaH/serine/threonine PP2A family protein phosphatase COG0640 DNA-binding transcriptional ArsR family regulator COG0641 sulfatase maturation enzyme AslB (radical SAM superfamily) COG0642 signal transduction histidine kinase COG0643 chemotaxis protein histidine kinase CheA COG0644 flavin-dependent dehydrogenase COG0645 predicted kinase COG0646 methionine synthase I (cobalamin-dependent) COG0647 ribonucleotide monophosphatase NagD (HAD superfamily) COG0648 endonuclease IV COG0649 NADH:ubiquinone oxidoreductase subunit D COG0650 formate hydrogenlyase subunit 4 COG0651 formate hydrogenlyase subunit 3/multisubunit Na+/H+ antiporter MnhD subunit COG0652 cyclophilin family peptidyl-prolyl cis-trans isomerase COG0653 preprotein translocase subunit SecA COG0654 2-polyprenyl-6-methoxyphenol hydroxylase-like FAD-dependent oxidoreductase COG0655 multimeric flavodoxin WrbA COG0656 diketogulonate reductase-like aldo/keto reductase COG0657 acetyl esterase/lipase COG0658 predicted membrane metal-binding protein COG0659 MFS superfamily sulfate permease-like transporter COG0661 predicted unusual protein kinase regulating ubiquinone biosynthesis (AarF/ABC1/UbiB family) COG0662 mannose-6-phosphate isomerase-like protein (cupin superfamily) COG0663 carbonic anhydrase/acetyltransferase-like protein (isoleucine patch superfamily) COG0664 CRP-like cAMP-binding protein COG0665 glycine/D-amino acid oxidase-like deaminating enzyme COG0666 ankyrin repeat protein COG0667 aryl-alcohol dehydrogenase-like predicted oxidoreductase COG0668 small-conductance mechanosensitive channel COG0669 phosphopantetheine adenylyltransferase COG0670 FtsH-binding integral membrane protein COG0671 membrane-associated phospholipid phosphatase COG0672 high-affinity Fe2+/Pb2+ permease COG0673 predicted dehydrogenase COG0674 pyruvate/2-oxoacid:ferredoxin oxidoreductase alpha subunit COG0675 transposase COG0676 D-hexose-6-phosphate mutarotase COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase COG0678 peroxiredoxin COG0679 predicted permease COG0680 Ni,Fe-hydrogenase maturation factor COG0681 signal peptidase I COG0682 prolipoprotein diacylglyceryltransferase COG0683 ABC-type branched-subunit amino acid transport system substrate-binding protein COG0684 regulator of RNase E activity RraA COG0685 5,10-methylenetetrahydrofolate reductase COG0686 alanine dehydrogenase COG0687 spermidine/putrescine-binding protein COG0688 phosphatidylserine decarboxylase COG0689 ribonuclease PH COG0690 preprotein translocase subunit SecE COG0691 tmRNA-binding protein COG0692 uracil DNA glycosylase COG0693 putative intracellular protease/amidase COG0694 Fe-S cluster biogenesis protein NfuA COG0695 glutaredoxin COG0696 bisphosphoglycerate-independent phosphoglycerate mutase (AlkP superfamily) COG0697 drug/metabolite transporter (DMT)-like permease COG0698 ribose 5-phosphate isomerase RpiB COG0699 replication fork clamp-binding protein CrfC COG0700 spore maturation protein SpmB COG0701 uncharacterized membrane protein YraQ (UPF0718 family) COG0702 uncharacterized protein YbjT (DUF2867 family) COG0703 shikimate kinase COG0704 phosphate uptake regulator COG0705 membrane associated rhomboid family serine protease COG0706 membrane protein insertase Oxa1/YidC/SpoIIIJ COG0707 UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase COG0708 exonuclease III COG0709 selenophosphate synthase COG0710 3-dehydroquinate dehydratase COG0711 F0F1-type ATP synthase membrane subunit b/b' COG0712 F0F1-type ATP synthase delta subunit COG0713 NADH:ubiquinone oxidoreductase subunit K COG0714 MoxR-like ATPase COG0715 ABC-type nitrate/sulfonate/bicarbonate transport system substrate-binding protein COG0716 flavodoxin COG0717 deoxycytidine triphosphate deaminase COG0718 DNA-binding protein YbaB COG0719 Fe-S cluster assembly scaffold protein SufB COG0720 6-pyruvoyl-tetrahydropterin synthase COG0721 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase C subunit COG0722 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase COG0723 Rieske Fe-S protein COG0724 RNA recognition motif-containing protein COG0725 ABC-type molybdate transport system substrate-binding protein COG0726 peptidoglycan/xylan/chitin deacetylase (PgdA/CDA1 family) COG0727 Fe-S-cluster containining protein COG0728 peptidoglycan biosynthesis protein MviN/MurJ (putative lipid II flippase) COG0729 outer membrane translocation and assembly module TamA COG0730 uncharacterized membrane protein YfcA COG0731 wyosine [tRNA(Phe)-imidazoG37] synthetase (radical SAM superfamily) COG0732 restriction endonuclease S subunit COG0733 SNF family Na+-dependent transporter COG0735 Fe2+ or Zn2+ uptake regulation protein COG0736 phosphopantetheinyl transferase (holo-ACP synthase) COG0737 2',3'-cyclic-nucleotide 2'-phosphodiesterase (5'-nucleotidase family) COG0738 fucose permease COG0739 murein DD-endopeptidase MepM/ murein hydrolase activator NlpD COG0740 ATP-dependent protease ClpP protease subunit COG0741 soluble lytic murein transglycosylase-like protein COG0742 16S rRNA G966 N2-methylase RsmD COG0743 1-deoxy-D-xylulose 5-phosphate reductoisomerase COG0744 membrane peptidoglycan carboxypeptidase COG0745 DNA-binding response OmpR family regulator COG0746 molybdopterin-guanine dinucleotide biosynthesis protein A COG0747 ABC-type transport system substrate-binding protein COG0748 putative heme iron utilization protein COG0749 DNA polymerase I-like protein with 3'-5' exonuclease and polymerase domains COG0750 membrane-associated protease RseP (regulator of RpoE activity) COG0751 glycyl-tRNA synthetase beta subunit COG0752 glycyl-tRNA synthetase alpha subunit COG0753 catalase COG0754 glutathionylspermidine synthase COG0755 ABC-type transport system involved in cytochrome c biogenesis permease subunit COG0756 dUTPase COG0757 3-dehydroquinate dehydratase COG0758 predicted Rossmann fold nucleotide-binding protein DprA/Smf involved in DNA uptake COG0759 putative component of membrane protein insertase Oxa1/YidC/SpoIIIJ protein YidD COG0760 parvulin-like peptidyl-prolyl isomerase COG0761 4-hydroxy-3-methylbut-2-enyl diphosphate reductase IspH COG0762 uncharacterized protein YggT (Ycf19 family) COG0763 lipid A disaccharide synthetase COG0764 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase COG0765 ABC-type amino acid transport system permease subunit COG0766 UDP-N-acetylglucosamine enolpyruvyl transferase COG0767 ABC-type transporter Mla maintaining outer membrane lipid asymmetry permease subunit MlaE COG0768 cell division protein FtsI/penicillin-binding protein 2 COG0769 UDP-N-acetylmuramyl tripeptide synthase COG0770 UDP-N-acetylmuramyl pentapeptide synthase COG0771 UDP-N-acetylmuramoylalanine-D-glutamate ligase COG0772 cell division protein FtsW (lipid II flippase) COG0773 UDP-N-acetylmuramate-alanine ligase COG0774 UDP-3-O-acyl-N-acetylglucosamine deacetylase COG0775 nucleoside phosphorylase COG0776 nucleoid DNA-binding protein COG0777 acetyl-CoA carboxylase beta subunit COG0778 nitroreductase COG0779 ribosome maturation factor RimP COG0780 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF COG0781 transcription termination factor NusB COG0782 transcription elongation GreA/GreB family factor COG0783 DNA-binding ferritin-like protein COG0784 CheY-like chemotaxis protein COG0785 cytochrome c biogenesis protein CcdA COG0786 Na+/glutamate symporter COG0787 alanine racemase COG0788 formyltetrahydrofolate hydrolase COG0789 DNA-binding transcriptional MerR regulator COG0790 TPR repeat protein COG0791 cell wall-associated NlpC family hydrolase COG0792 Holliday junction resolvase-like predicted endonuclease COG0793 C-terminal processing protease CtpA/Prc COG0794 D-arabinose 5-phosphate isomerase GutQ COG0795 lipopolysaccharide export LptBFGC system permease protein LptF COG0796 glutamate racemase COG0797 rare lipoprotein A (peptidoglycan hydrolase) COG0798 ACR3 family arsenite efflux pump ArsB COG0799 ribosomal silencing factor RsfS COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase COG0802 tRNA A37 threonylcarbamoyladenosine biosynthesis protein TsaE COG0803 ABC-type Zn uptake system ZnuABC Zn-binding protein ZnuA COG0804 urease alpha subunit COG0805 Sec-independent protein secretion pathway component TatC COG0806 ribosomal 30S subunit maturation factor RimM COG0807 GTP cyclohydrolase II COG0809 S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) COG0810 outer membrane biosynthesis protein TonB COG0811 biopolymer transport protein ExbB/TolQ COG0812 UDP-N-acetylenolpyruvoylglucosamine reductase COG0813 purine-nucleoside phosphorylase COG0814 amino acid permease COG0815 apolipoprotein N-acyltransferase COG0816 RNase H-fold protein (predicted Holliday junction resolvase) COG0817 Holliday junction resolvasome RuvABC endonuclease subunit COG0818 diacylglycerol kinase COG0819 thiaminase COG0820 adenine C2-methylase RlmN of 23S rRNA A2503 and tRNA A37 COG0821 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase IspG/GcpE COG0822 NifU-like protein involved in Fe-S cluster formation COG0823 Tol biopolymer transport system component COG0824 acyl-CoA thioesterase FadM COG0825 acetyl-CoA carboxylase alpha subunit COG0826 collagenase-like PrtC family protease COG0827 adenine-specific DNA methylase COG0828 ribosomal protein S21 COG0829 urease accessory protein UreH COG0830 urease accessory protein UreF COG0831 urease gamma subunit COG0832 urease beta subunit COG0833 amino acid permease COG0834 ABC-type amino acid transport substrate-binding protein COG0835 chemotaxis signal transduction protein COG0836 mannose-1-phosphate guanylyltransferase COG0837 glucokinase COG0838 NADH:ubiquinone oxidoreductase subunit 3 (subunit A) COG0839 NADH:ubiquinone oxidoreductase subunit 6 (subunit J) COG0840 methyl-accepting chemotaxis protein COG0841 multidrug efflux pump subunit AcrB COG0842 ABC-type multidrug transport system permease subunit COG0843 heme/copper-type cytochrome/quinol oxidase subunit 1 COG0845 multidrug efflux pump subunit AcrA (membrane-fusion protein) COG0846 NAD-dependent SIR2 family protein deacetylase COG0847 DNA polymerase III epsilon subunit-like protein COG0848 biopolymer transport protein ExbD COG0849 cell division ATPase FtsA COG0850 septum formation inhibitor MinC COG0851 septum formation topological specificity factor MinE COG0852 NADH:ubiquinone oxidoreductase subunit C COG0853 aspartate 1-decarboxylase COG0854 pyridoxine 5'-phosphate synthase PdxJ COG0855 polyphosphate kinase COG0856 orotate phosphoribosyltransferase-like protein COG0857 BioD-like phosphotransacetylase family protein COG0858 ribosome-binding factor A COG0859 ADP-heptose:LPS heptosyltransferase COG0860 N-acetylmuramoyl-L-alanine amidase COG0861 predicted tellurium resistance membrane protein TerC COG0863 DNA modification methylase COG0864 metal-responsive CopG/Arc/MetJ family transcriptional regulator COG1001 adenine deaminase COG1002 type II restriction/modification system DNA methylase subunit YeeA COG1003 glycine cleavage system protein P-like pyridoxal-binding family COG1004 UDP-glucose 6-dehydrogenase COG1005 NADH:ubiquinone oxidoreductase subunit H COG1006 multisubunit Na+/H+ antiporter MnhC subunit COG1007 NADH:ubiquinone oxidoreductase subunit 2 (subunit N) COG1008 NADH:ubiquinone oxidoreductase subunit 4 (subunit M) COG1009 NADH:ubiquinone oxidoreductase subunit 5 (subunit L)/multisubunit Na+/H+ antiporter MnhA subunit COG1010 precorrin-3B methylase COG1011 FMN phosphatase YigB (HAD superfamily) COG1012 acyl-CoA reductase-like NAD-dependent aldehyde dehydrogenase COG1013 pyruvate/2-oxoacid:ferredoxin oxidoreductase beta subunit COG1014 Pyruvate/2-oxoacid:ferredoxin oxidoreductase gamma subunit COG1015 phosphopentomutase COG1017 hemoglobin-like flavoprotein COG1018 ferredoxin-NADP reductase COG1019 phosphopantetheine adenylyltransferase COG1020 non-ribosomal peptide synthetase component F COG1021 non-ribosomal peptide synthetase component E (peptide arylation enzyme) COG1022 long-subunit acyl-CoA synthetase (AMP-forming) COG1023 6-phosphogluconate dehydrogenase (decarboxylating) COG1024 enoyl-CoA hydratase/carnithine racemase COG1025 secreted Zn-dependent insulinase-like peptidase COG1026 Zn-dependent M16 (insulinase) family peptidase COG1027 aspartate ammonia-lyase COG1028 NAD(P)-dependent dehydrogenase (short-subunit alcohol dehydrogenase family) COG1029 formylmethanofuran dehydrogenase subunit B COG1030 membrane-bound ClpP family serine protease COG1031 radical SAM superfamily enzyme with C-terminal helix-hairpin-helix motif COG1032 radical SAM superfamily enzyme YgiQ (UPF0313 family) COG1033 predicted RND superfamily exporter protein COG1034 NADH dehydrogenase/NADH:ubiquinone oxidoreductase subunit G COG1035 coenzyme F420-reducing hydrogenase beta subunit COG1036 flavoprotein COG1038 pyruvate carboxylase COG1039 ribonuclease HIII COG1040 predicted amidophosphoribosyltransferase COG1041 tRNA G10 N-methylase Trm11 COG1042 acyl-CoA synthetase (NDP forming) COG1043 acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase COG1044 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase COG1045 serine acetyltransferase COG1047 FKBP-type peptidyl-prolyl cis-trans isomerase 2 COG1048 aconitase A COG1049 aconitase B COG1051 ADP-ribose pyrophosphatase YjhB (NUDIX family) COG1052 lactate dehydrogenase-like 2-hydroxyacid dehydrogenase COG1053 succinate dehydrogenase/fumarate reductase flavoprotein subunit COG1054 predicted sulfurtransferase COG1055 Na+/H+ antiporter NhaD/arsenite permease-like protein COG1056 nicotinamide mononucleotide adenylyltransferase COG1057 nicotinic acid mononucleotide adenylyltransferase COG1058 molybdopterin-biosynthesis enzyme MoeA-like protein COG1059 thermostable 8-oxoguanine DNA glycosylase COG1060 2-iminoacetate synthase ThiH COG1061 superfamily II DNA or RNA helicase COG1062 Zn-dependent alcohol dehydrogenase COG1063 threonine dehydrogenase-like Zn-dependent dehydrogenase COG1064 D-arabinose 1-dehydrogenase-like Zn-dependent alcohol dehydrogenase COG1066 predicted ATP-dependent serine protease COG1067 predicted ATP-dependent protease COG1069 ribulose kinase COG1070 sugar (pentulose or hexulose) kinase COG1071 TPP-dependent pyruvate/acetoin dehydrogenase alpha subunit COG1072 pantothenate kinase COG1073 fermentation-respiration switch protein FrsA (DUF1100 family) COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit COG1075 triacylglycerol esterase/lipase EstA (alpha/beta hydrolase family) COG1076 DnaJ-domain-containing protein 1 COG1077 actin-like ATPase involved in cell morphogenesis COG1078 HD superfamily phosphohydrolase COG1079 ABC-type uncharacterized transport system permease subunit COG1080 phosphoenolpyruvate-protein kinase (PTS system EI component) COG1082 sugar phosphate isomerase/epimerase COG1083 CMP-N-acetylneuraminic acid synthetase COG1084 GTP1/Obg family GTP-binding protein COG1085 galactose-1-phosphate uridylyltransferase COG1086 FlaA1/EpsC-like NDP-sugar epimerase COG1087 UDP-glucose 4-epimerase COG1088 dTDP-D-glucose 4,6-dehydratase COG1089 GDP-D-mannose dehydratase COG1090 NAD dependent epimerase/dehydratase family enzyme COG1091 dTDP-4-dehydrorhamnose reductase COG1092 23S rRNA G2069 N7-methylase RlmK/C1962 C5-methylase RlmI COG1093 translation initiation factor 2 alpha subunit (eIF-2alpha) COG1094 rRNA processing protein Krr1/Pno1 COG1095 DNA-directed RNA polymerase subunit E'/Rpb7 COG1096 exosome complex RNA-binding protein Csl4 COG1097 exosome complex RNA-binding protein Rrp4 COG1098 predicted RNA-binding protein with RPS1 domain COG1099 predicted metal-dependent TIM-barrel fold hydrolase COG1100 GTPase SAR1 family protein COG1101 ABC-type uncharacterized transport system ATPase component COG1102 cytidylate kinase COG1103 Cys-tRNA synthase (O-phospho-L-seryl-tRNA:Cys-tRNA synthase) COG1104 cysteine sulfinate desulfinase/cysteine desulfurase-like protein COG1105 fructose-1-phosphate kinase PfkB-like protein COG1106 AAA15 family ATPase/GTPase COG1107 RecJ-like exonuclease COG1108 ABC-type Mn2+/Zn2+ transport system permease subunit COG1109 phosphomannomutase COG1110 reverse gyrase COG1111 ERCC4-related helicase COG1112 superfamily I DNA and/or RNA helicase COG1113 L-asparagine transporter-like permease COG1114 branched-subunit amino acid permease COG1115 Na+/alanine symporter COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system ATPase subunit COG1117 ABC-type phosphate transport system ATPase subunit COG1118 ABC-type sulfate/molybdate transport systems ATPase subunit COG1119 ABC-type molybdenum transport system ATPase subunit/photorepair protein PhrA COG1120 ABC-type cobalamin/Fe3+-siderophores transport system ATPase subunit COG1121 ABC-type Mn2+/Zn2+ transport system ATPase subunit COG1122 energy-coupling factor transporter ATP-binding protein EcfA2 COG1123 ABC-type glutathione transport system ATPase component COG1124 ABC-type dipeptide/oligopeptide/nickel transport system ATPase subunit COG1125 ABC-type proline/glycine betaine transport system ATPase subunit COG1126 ABC-type polar amino acid transport system ATPase subunit COG1127 ABC-type transporter Mla maintaining outer membrane lipid asymmetry ATPase subunit MlaF COG1129 ABC-type sugar transport system ATPase subunit COG1131 ABC-type multidrug transport system ATPase subunit COG1132 ABC-type multidrug transport system fused ATPase/permease subunit COG1133 ABC-type long-subunit fatty acid transport system fused permease/ATPase subunit COG1134 ABC-type polysaccharide/polyol phosphate transport system ATPase subunit COG1135 ABC-type methionine transport system ATPase subunit COG1136 ABC-type lipoprotein export system ATPase subunit COG1137 ABC-type lipopolysaccharide export system ATPase subunit COG1138 cytochrome c biogenesis factor COG1139 L-lactate utilization protein LutB COG1140 nitrate reductase beta subunit COG1141 ferredoxin COG1142 Fe-S-cluster-containing hydrogenase component 2 COG1143 formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase subunit I COG1144 Pyruvate/2-oxoacid:ferredoxin oxidoreductase delta subunit COG1145 ferredoxin COG1146 NAD-dependent dihydropyrimidine dehydrogenase PreA subunit COG1148 heterodisulfide reductase subunit A-like polyferredoxin COG1149 MinD superfamily P-loop ATPase COG1150 heterodisulfide reductase subunit C COG1151 hydroxylamine reductase (hybrid-cluster protein) COG1152 CO dehydrogenase/acetyl-CoA synthase alpha subunit COG1153 formylmethanofuran dehydrogenase subunit D COG1154 deoxyxylulose-5-phosphate synthase COG1155 vacuolar-type H+-ATPase catalytic subunit A/Vma1 COG1156 vacuolar-type H+-ATPase subunit B/Vma2 COG1157 flagellar biosynthesis/type III secretory pathway ATPase COG1158 transcription termination factor Rho COG1159 GTPase Era involved in 16S rRNA processing COG1160 predicted GTPase COG1161 ribosome biogenesis GTPase A COG1162 putative ribosome biogenesis GTPase RsgA COG1163 ribosome-interacting GTPase 1 COG1164 oligoendopeptidase F COG1165 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase COG1166 arginine decarboxylase-like protein COG1167 DNA-binding transcriptional MocR family regulator COG1168 bifunctional pyridoxal-dependent enzyme with beta-cystathionase and maltose regulon repressor activities COG1169 isochorismate synthase EntC COG1171 threonine dehydratase COG1172 ribose/xylose/arabinose/galactoside ABC-type transport system permease subunit COG1173 ABC-type dipeptide/oligopeptide/nickel transport system permease subunit COG1174 ABC-type proline/glycine betaine transport system permease subunit COG1175 ABC-type sugar transport system permease subunit COG1176 ABC-type spermidine/putrescine transport system permease subunit I COG1177 ABC-type spermidine/putrescine transport system permease subunit II COG1178 ABC-type Fe3+ transport system permease subunit COG1179 tRNA A37 threonylcarbamoyladenosine dehydratase COG1180 pyruvate-formate lyase-activating enzyme COG1181 D-alanine-D-alanine ligase-like ATP-grasp enzyme COG1182 FMN-dependent NADH-azoreductase COG1183 phosphatidylserine synthase COG1184 translation initiation factor 2B subunit (eIF-2B alpha/beta/delta family) COG1185 polyribonucleotide nucleotidyltransferase COG1186 protein subunit release factor B COG1187 16S rRNA U516 pseudouridylate synthase RsuA-like enzyme COG1188 ribosomal 50S subunit-recycling heat shock protein COG1189 predicted rRNA methylase YqxC with S4 and FtsJ domains COG1190 lysyl-tRNA synthetase class II COG1191 DNA-directed RNA polymerase specialized sigma subunit COG1192 cellulose biosynthesis protein BcsQ COG1193 dsDNA-specific endonuclease/ATPase MutS2 COG1194 adenine-specific DNA glycosylase COG1195 recombinational DNA repair ATPase RecF COG1196 chromosome segregation ATPase COG1197 transcription-repair coupling factor (superfamily II helicase) COG1198 primosomal protein N' COG1199 Rad3-related DNA helicase COG1200 RecG-like helicase COG1201 Lhr-like helicase COG1202 superfamily II helicase COG1203 CRISPR/Cas system-associated endonuclease/helicase Cas3 COG1204 replicative superfamily II helicase COG1205 ATP-dependent helicase YprA (DUF1998 family) COG1206 folate-dependent tRNA-U54 methylase TrmFO/GidA COG1207 bifunctional N-acetylglucosamine-1-phosphate-uridyltransferase/glucosamine-1-phosphate-acetyltransferase GlmU-like protein COG1208 NDP-sugar pyrophosphorylase family protein COG1209 dTDP-glucose pyrophosphorylase COG1210 UTP-glucose-1-phosphate uridylyltransferase COG1211 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase COG1212 CMP-2-keto-3-deoxyoctulosonic acid synthetase COG1213 choline kinase COG1214 tRNA A37 threonylcarbamoyladenosine modification protein TsaB COG1215 cellulose synthase/poly-beta-1,6-N-acetylglucosamine synthase-like glycosyltransferase COG1216 GT2 family glycosyltransferase COG1217 predicted membrane GTPase involved in stress response COG1218 3'-phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase COG1219 ATP-dependent protease Clp ATPase subunit COG1220 ATP-dependent protease HslVU (ClpYQ) ATPase subunit COG1221 transcriptional regulator with AAA-type ATPase domain COG1222 ATP-dependent 26S proteasome regulatory subunit COG1223 AAA+ superfamily predicted ATPase COG1224 DNA helicase TIP49 (TBP-interacting protein) COG1225 peroxiredoxin COG1226 voltage-gated potassium channel Kch COG1227 inorganic pyrophosphatase/exopolyphosphatase COG1228 imidazolonepropionase-like amidohydrolase COG1229 formylmethanofuran dehydrogenase subunit A COG1230 Co/Zn/Cd efflux system component COG1231 monoamine oxidase COG1232 protoporphyrinogen oxidase COG1233 phytoene dehydrogenase-like protein COG1234 ribonuclease BN (tRNA processing enzyme) COG1235 phosphoribosyl 1,2-cyclic phosphodiesterase COG1236 Cft2 family RNA processing exonuclease COG1237 metal-dependent hydrolase (beta-lactamase superfamily II) COG1238 membrane protein YqaA with SNARE-associated domain COG1239 Mg-chelatase subunit ChlI COG1240 Mg-chelatase subunit ChlD COG1241 DNA replicative helicase MCM subunit Mcm2 (Cdc46/Mcm family) COG1242 radical SAM superfamily enzyme COG1243 histone acetyltransferase (RNA polymerase elongator complex component) COG1244 uncharacterized Fe-S cluster-containing MiaB family protein COG1245 translation initiation factor RLI1 COG1246 N-acetylglutamate synthase-like GNAT family acetyltransferase COG1247 L-amino acid N-acyltransferase YncA COG1249 pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3) component COG1250 3-hydroxyacyl-CoA dehydrogenase COG1251 NAD(P)H-nitrite reductase large subunit COG1252 NADH dehydrogenase FAD-containing subunit COG1253 CBS domain containing-hemolysin-like protein COG1254 acylphosphatase COG1255 uncharacterized UPF0146 family protein COG1256 flagellar hook-associated protein FlgK COG1257 hydroxymethylglutaryl-CoA reductase COG1258 tRNA U54 and U55 pseudouridine synthase Pus10 COG1259 bifunctional DNase/RNase COG1260 myo-inositol-1-phosphate synthase COG1261 flagella basal body P-ring formation protein FlgA COG1262 formylglycine-generating enzyme required for sulfatase activity COG1263 phosphotransferase system glucose/maltose/N-acetylglucosamine-specific IIC component COG1264 phosphotransferase system IIB component COG1266 membrane protease YdiL (CAAX protease family) COG1267 phosphatidylglycerophosphatase A COG1268 biotin transporter BioY COG1269 vacuolar-type H+-ATPase subunit I/STV1 COG1270 cobalamin biosynthesis protein CobD/CbiB COG1271 cytochrome bd-type quinol oxidase subunit 1 COG1272 predicted membrane channel-forming protein YqfA (hemolysin III family) COG1273 non-homologous end joining protein Ku COG1274 GTP-dependent phosphoenolpyruvate carboxykinase COG1275 tellurite resistance protein TehA-like permease COG1276 putative copper export protein COG1277 ABC-type transport system involved in multi-copper enzyme maturation permease subunit COG1278 cold shock CspA family protein COG1279 arginine exporter protein ArgO COG1280 threonine/homoserine/homoserine lactone efflux protein COG1281 redox-regulated HSP33 family molecular chaperone COG1282 NAD/NADP transhydrogenase beta subunit COG1283 Na+/phosphate symporter COG1284 uncharacterized membrane-anchored protein YitT (DUF2179 family) COG1285 uncharacterized membrane protein YhiD involved in acid resistance COG1286 uncharacterized membrane protein required for colicin V production COG1287 asparagine N-glycosylation enzyme membrane subunit Stt3 COG1288 uncharacterized ion transporter superfamily protein YfcC COG1289 uncharacterized membrane protein YccC COG1290 quinol-cytochrome oxidoreductase complex cytochrome b subunit COG1291 flagellar motor component MotA COG1292 choline-glycine betaine transporter COG1293 predicted ribosome quality control (RQC) complex YloA/Tae2 family protein COG1294 cytochrome bd-type quinol oxidase subunit 2 COG1295 uncharacterized BrkB/YihY/UPF0761 family membrane protein COG1296 predicted branched-subunit amino acid permease COG1297 uncharacterized oligopeptide transporter (OPT) family protein COG1298 flagellar biosynthesis component FlhA COG1299 fructose-specific phosphotransferase system IIC component COG1300 uncharacterized membrane protein SpoIIM required for sporulation COG1301 Na+/H+-dicarboxylate symporter COG1302 uncharacterized alkaline shock family protein YloU COG1303 predicted SpoU family rRNA methylase COG1304 isopentenyl diphosphate isomerase/L-lactate dehydrogenase-like FMN-dependent dehydrogenase COG1305 transglutaminase-like putative cysteine protease COG1306 hypothetical protein COG1307 fatty acid-binding protein DegV COG1308 NACalpha-BTF3-like transcription factor COG1309 AcrR family transcriptional regulator COG1310 proteasome lid subunit RPN8/RPN11 COG1311 DNA polymerase II small subunit/DNA polymerase delta subunit B COG1312 D-mannonate dehydratase COG1313 uncharacterized Fe-S radical SAM superfamily protein PflX COG1314 preprotein translocase subunit SecG COG1315 uncharacterized protein (DUF342 family) COG1316 anionic cell wall polymer biosynthesis LytR-Cps2A-Psr (LCP) family protein COG1317 flagellar biosynthesis/type III secretory pathway protein FliH COG1318 predicted transcriptional regulator COG1319 CO/xanthine dehydrogenase FAD-binding subunit COG1320 multisubunit Na+/H+ antiporter MnhG subunit COG1321 Mn-dependent DtxR family transcriptional regulator COG1322 DNA anti-recombination protein RmuC COG1323 predicted nucleotidyltransferase COG1324 uncharacterized protein involved in tolerance to divalent cations COG1325 RNA binding exosome subunit COG1326 uncharacterized Zn finger protein COG1327 transcriptional regulator NrdR family protein COG1328 anaerobic ribonucleoside-triphosphate reductase COG1329 RNA polymerase-interacting CarD/CdnL/TRCF family regulator COG1330 exonuclease V gamma subunit COG1331 uncharacterized protein YyaL (SSP411 family) COG1332 CRISPR/Cas system CSM-associated protein Csm5 (group 7 of RAMP superfamily) COG1333 cytochrome c biogenesis protein ResB COG1334 uncharacterized FlaG/YvyC family protein COG1335 nicotinamidase-related amidase COG1336 CRISPR/Cas system CMR subunit Cmr4 (Cas7 group RAMP superfamily) COG1337 CRISPR/Cas system CSM-associated protein Csm3 (group 7 of RAMP superfamily) COG1338 flagellar biosynthesis protein FliP COG1339 CTP-dependent riboflavin kinase COG1340 uncharacterized coiled-coil DUF342 family protein COG1341 polynucleotide 5'-kinase involved in rRNA processing COG1342 predicted DNA-binding protein (UPF0251 family) COG1343 CRISPR/Cas system-associated endoribonuclease Cas2 COG1344 flagellin-like hook-associated protein FlgL COG1345 flagellar capping protein FliD COG1346 putative effector of murein hydrolase COG1347 Na+-transporting NADH:ubiquinone oxidoreductase subunit NqrD COG1348 nitrogenase subunit NifH COG1349 DeoR/GlpR family transcriptional regulator of sugar metabolism COG1350 predicted alternative tryptophan synthase beta-subunit COG1351 thymidylate synthase ThyX COG1352 chemotaxis methyl-accepting protein methylase COG1353 CRISPR/Cas system-associated protein Cas10 (large subunit of type III CRISPR-Cas system) COG1354 chromatin segregation and condensation protein Rec8/ScpA/Scc1 (kleisin family) COG1355 predicted class III extradiol MEMO1 family dioxygenase COG1356 transcriptional regulator COG1357 uncharacterized protein YjbI with pentapeptide repeats COG1358 ribosomal protein L7Ae-like RNA K-turn-binding protein COG1359 quinol monooxygenase YgiN COG1360 flagellar motor protein MotB COG1361 hypothetical protein COG1362 aspartyl aminopeptidase COG1363 putative aminopeptidase FrvX COG1364 N-acetylglutamate synthase/N-acetylornithine aminotransferase COG1365 predicted PP-loop superfamily ATPase COG1366 anti-anti-sigma regulatory factor COG1367 CRISPR/Cas system CMR-associated protein Cmr1 (group 7 of RAMP superfamily) COG1368 phosphoglycerol transferase MdoB-like AlkP superfamily enzyme COG1369 RNase P/RNase MRP subunit POP5 COG1370 archaeosine-15-forming tRNA-guanine transglycosylase COG1371 SHS2 domain-containing protein COG1372 intein/homing endonuclease COG1373 predicted AAA+ superfamily ATPase COG1374 ribosome biogenesis protein Nip4 COG1376 lipoprotein-anchoring transpeptidase ErfK/SrfK COG1377 flagellar biosynthesis protein FlhB COG1378 sugar-specific transcriptional regulator TrmB COG1379 PHP family Zn ribbon phosphoesterase COG1380 putative effector of murein hydrolase LrgA (UPF0299 family) COG1381 recombinational DNA repair protein (RecF pathway) COG1382 chaperonin cofactor prefoldin COG1383 ribosomal protein S17E COG1384 lysyl-tRNA synthetase class I COG1385 16S rRNA U1498 N3-methylase RsmE COG1386 chromosome segregation and condensation protein ScpB COG1387 histidinol phosphatase-like PHP family hydrolase COG1388 LysM repeat protein COG1389 DNA topoisomerase VI subunit B COG1390 vacuolar-type H+-ATPase subunit E/Vma4 COG1391 glutamine synthetase adenylyltransferase COG1392 uncharacterized protein Yka (UPF0111/DUF47 family) COG1393 arsenate reductase-like glutaredoxin family protein COG1394 vacuolar-type H+-ATPase subunit D/Vma8 COG1395 predicted transcriptional regulator COG1396 transcriptional regulator with XRE-family HTH domain COG1397 ADP-ribosylglycohydrolase COG1398 fatty-acid desaturase COG1399 uncharacterized metal-binding protein YceD (DUF177 family) COG1400 signal recognition particle subunit SEC65 COG1401 5-methylcytosine-specific restriction endonuclease McrBC GTP-binding regulatory subunit McrB COG1402 creatinine amidohydrolase/Fe(II)-dependent formamide hydrolase-like protein COG1403 5-methylcytosine-specific restriction endonuclease McrA COG1404 subtilisin family serine protease COG1405 transcription initiation factor TFIIIB Brf1 subunit/transcription initiation factor TFIIB COG1406 CheY-specific phosphatase CheX COG1407 metallophosphoesterase superfamily enzyme COG1408 predicted MPP superfamily phosphohydrolase COG1409 3',5'-cyclic AMP phosphodiesterase CpdA COG1410 cobalamin-dependent methionine synthase I COG1411 uncharacterized protein related to proFAR isomerase COG1412 rRNA-processing protein FCF1 COG1413 HEAT repeat protein COG1414 DNA-binding IclR family transcriptional regulator COG1415 hypothetical protein COG1416 intracellular sulfur oxidation DsrE/DsrF family protein COG1417 hypothetical protein COG1418 HD superfamily phosphodiesterase COG1419 flagellar biosynthesis GTPase FlhF COG1420 transcriptional regulator of heat shock response COG1421 CRISPR/Cas system CSM-associated protein Csm2 small subunit COG1422 uncharacterized membrane protein (DUF106 family) COG1423 ATP-dependent RNA circularization protein (DNA/RNA ligase family) COG1424 pimeloyl-CoA synthetase COG1426 cytoskeletal protein RodZ COG1427 predicted solute-binding protein COG1428 deoxyadenosine/deoxycytidine kinase COG1429 cobalamin biosynthesis Mg chelatase CobN COG1430 uncharacterized membrane protein (UPF0127 family) COG1431 argonaute-like protein implicated in RNA metabolism and viral defense COG1432 uncharacterized LabA/DUF88 family protein COG1433 predicted Fe-Mo cluster-binding NifX family protein COG1434 uncharacterized SAM-binding protein YcdF (DUF218 family) COG1435 thymidine kinase COG1436 vacuolar-type H+-ATPase subunit F/Vma7 COG1437 adenylate cyclase class IV COG1438 arginine repressor COG1439 rRNA maturation endonuclease Nob1 COG1440 cellobiose-specific phosphotransferase system component IIB COG1441 O-succinylbenzoate synthase COG1442 lipopolysaccharide biosynthesis glycosyltransferase COG1443 isopentenyldiphosphate isomerase COG1444 tRNA(Met) C34 N-acetyltransferase TmcA COG1445 fructose-specific phosphotransferase system component IIB COG1446 isoaspartyl peptidase/L-asparaginase-like protein (Ntn-hydrolase superfamily) COG1447 cellobiose-specific phosphotransferase system component IIA COG1448 aspartate/tyrosine/aromatic aminotransferase COG1449 alpha-amylase/alpha-mannosidase (GH57 family) COG1450 type II secretory pathway component GspD/PulD (secretin) COG1451 predicted metal-dependent hydrolase COG1452 lipopolysaccharide assembly outer membrane protein LptD (OstA) COG1453 predicted aldo/keto reductase-like oxidoreductase COG1454 alcohol dehydrogenase class IV COG1455 cellobiose-specific phosphotransferase system component IIC COG1456 CO dehydrogenase/acetyl-CoA synthase gamma subunit (corrinoid Fe-S protein) COG1457 purine-cytosine permease-like protein COG1458 predicted DNA-binding protein (UPF0278 family) COG1459 type II secretory pathway component PulF COG1460 DNA-directed RNA polymerase subunit F COG1461 dihydroxyacetone kinase-like predicted kinase COG1462 curli biogenesis system outer membrane secretion channel CsgG COG1463 ABC-type transporter Mla subunit MlaD COG1464 ABC-type metal ion transport system substrate-binding protein COG1465 3-dehydroquinate synthase class II COG1466 DNA polymerase III delta subunit COG1467 DNA primase catalytic subunit COG1468 CRISPR/Cas system-associated exonuclease Cas4 (RecB family) COG1469 GTP cyclohydrolase FolE2 COG1470 uncharacterized membrane protein COG1471 ribosomal protein S4E COG1472 beta-glucosidase-like glycosyl hydrolase COG1473 metal-dependent amidase/aminoacylase/carboxypeptidase family protein COG1474 Cdc6-like AAA superfamily ATPase COG1475 ParB-like chromosome segregation protein Spo0J COG1476 DNA-binding XRE family transcriptional regulator COG1477 thiamine biosynthesis lipoprotein ApbE COG1478 F420-0:gamma-glutamyl ligase COG1479 uncharacterized protein with ParB-like and HNH nuclease domain COG1480 membrane-associated HD superfamily phosphohydrolase COG1481 DNA-binding transcriptional regulator WhiA COG1482 mannose-6-phosphate isomerase class I COG1483 predicted AAA+ superfamily ATPase COG1484 DNA replication protein DnaC COG1485 predicted ATPase COG1486 alpha-galactosidase/6-phospho-beta-glucosidase family protein COG1487 predicted nucleic acid-binding protein COG1488 nicotinic acid phosphoribosyltransferase COG1489 DNA-binding sugar fermentation-stimulating protein COG1490 D-Tyr-tRNAtyr deacylase COG1491 predicted nucleic acid-binding OB-fold protein COG1492 cobyric acid synthase COG1493 serine kinase of HPr protein (carbohydrate metabolism regulator) COG1494 fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase-like protein COG1495 disulfide bond formation protein DsbB COG1496 copper oxidase (laccase) domain-containing protein COG1497 predicted transcriptional regulator COG1498 RNA processing factor Prp31 COG1499 NMD protein affecting ribosome stability and mRNA decay COG1500 ribosome maturation protein Sdo1 COG1501 alpha-glucosidase (family GH31 glycosyl hydrolase) COG1502 phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase-like enzyme COG1503 peptide subunit release factor 1 (eRF1) COG1504 hypothetical protein COG1505 prolyl oligopeptidase PreP (S9A serine peptidase family) COG1506 dipeptidyl aminopeptidase/acylaminoacyl peptidase COG1507 hypothetical protein COG1508 DNA-directed RNA polymerase specialized sigma54-like protein COG1509 L-lysine 2,3-aminomutase COG1510 DNA-binding transcriptional regulator GbsR (MarR family) COG1511 uncharacterized phage infection (PIP) family protein YhgE COG1512 uncharacterized membrane protein YgcG COG1513 cyanate lyase COG1514 2'-5' RNA ligase COG1515 deoxyinosine 3'endonuclease (endonuclease V) COG1516 flagellin-specific chaperone FliS COG1517 CRISPR/Cas system-associated protein Csx1 COG1518 CRISPR/Cas system-associated endonuclease Cas1 COG1519 3-deoxy-D-manno-octulosonic-acid transferase COG1520 outer membrane protein assembly factor BamB COG1521 pantothenate kinase type III COG1522 DNA-binding Lrp family transcriptional regulator COG1523 pullulanase/glycogen debranching enzyme COG1524 predicted AlkP superfamily pyrophosphatase or phosphodiesterase COG1525 endonuclease YncB( thermonuclease family) COG1526 formate dehydrogenase assembly factor FdhD COG1527 vacuolar-type H+-ATPase subunit C/Vma6 COG1528 ferritin COG1529 CO/xanthine dehydrogenase Mo-binding subunit COG1530 Ribonuclease G/E COG1531 uncharacterized protein (UPF0248 family) COG1532 predicted RNA-binding protein COG1533 DNA repair photolyase COG1534 RNA-binding protein YhbY COG1535 isochorismate hydrolase COG1536 flagellar motor switch protein FliG COG1537 stalled ribosome rescue protein Dom34 COG1538 outer membrane protein TolC COG1539 dihydroneopterin aldolase COG1540 lactam utilization protein B COG1541 phenylacetate-coenzyme A ligase PaaK-like adenylate-forming protein COG1542 hypothetical protein COG1543 predicted glycosyl hydrolase (DUF1957 family) COG1544 ribosome-associated translation inhibitor RaiA COG1545 uncharacterized OB-fold protein COG1546 nicotinamide mononucleotide (NMN) deamidase PncC COG1547 predicted metal-dependent hydrolase COG1548 uncharacterized hydantoinase/oxoprolinase family protein COG1549 predicted RNA-binding protein COG1550 uncharacterized protein YlxP (DUF503 family) COG1551 sRNA-binding carbon storage regulator CsrA COG1552 ribosomal protein L40E COG1553 sulfur relay (sulfurtransferase) complex TusBCD TusD component (DsrE family) COG1554 trehalose/maltose hydrolase-like predicted phosphorylase COG1555 DNA uptake protein ComE-like DNA-binding protein COG1556 L-lactate utilization protein LutC COG1558 flagellar basal body rod protein FlgC COG1559 cell division protein YceG involved in septum cleavage COG1560 lauroyl/myristoyl acyltransferase COG1561 uncharacterized protein YicC (UPF0701 family) COG1562 phytoene/squalene synthetase COG1563 uncharacterized MnhB-related membrane protein COG1564 thiamine pyrophosphokinase COG1565 SAM-dependent MidA family methyltransferase COG1566 multidrug resistance efflux pump COG1567 CRISPR/Cas system CSM-associated protein Csm4 (group 5 of RAMP superfamily) COG1568 predicted methyltransferase COG1569 predicted nucleic acid-binding protein COG1570 exonuclease VII large subunit COG1571 tRNA(Ile2) C34 agmatinyltransferase TiaS COG1572 subtilase family serine protease COG1573 uracil-DNA glycosylase COG1574 predicted amidohydrolase YtcJ COG1575 1,4-dihydroxy-2-naphthoate octaprenyltransferase COG1576 23S rRNA pseudoU1915 N3-methylase RlmH COG1577 mevalonate kinase COG1578 uncharacterized protein with ATP-grasp and redox domains COG1579 predicted nucleic acid-binding Zn-ribbon protein COG1580 flagellar basal body-associated protein FliL COG1581 DNA-binding protein COG1582 uncharacterized protein YlzI (FlbEa/FlbD family) COG1583 CRISPR/Cas system endoribonuclease Cas6 (RAMP superfamily) COG1584 succinate-acetate transporter protein COG1585 membrane protein implicated in regulation of membrane protease activity COG1586 S-adenosylmethionine/arginine decarboxylase-like enzyme COG1587 uroporphyrinogen-III synthase COG1588 RNase P/RNase MRP subunit p29 COG1589 cell division septal protein FtsQ COG1590 tRNA(Phe) wybutosine-synthesizing methylase Tyw3 COG1591 Holliday junction resolvase COG1592 rubrerythrin COG1593 TRAP-type C4-dicarboxylate transport system permease large subunit COG1594 DNA-directed RNA polymerase subunit M/transcription elongation factor TFIIS COG1595 DNA-directed RNA polymerase specialized sigma24 family protein COG1596 protein involved in polysaccharide export with SLBB domain COG1597 diacylglycerol kinase family enzyme COG1598 predicted RNase H-like HicB family nuclease COG1599 ssDNA-binding replication factor A large subunit COG1600 epoxyqueuosine reductase QueG COG1601 translation initiation factor 2 beta subunit (eIF-2beta)/eIF-5 COG1602 hypothetical protein COG1603 RNase P/RNase MRP subunit p30 COG1604 CRISPR/Cas system CMR subunit Cmr6 (Cas7 group RAMP superfamily) COG1605 chorismate mutase COG1606 PP-loop superfamily ATP-utilizing enzyme COG1607 acyl-CoA hydrolase COG1608 isopentenyl phosphate kinase COG1609 DNA-binding LacI/PurR family transcriptional regulator COG1610 uncharacterized protein YqeY COG1611 predicted Rossmann-fold nucleotide-binding protein COG1612 heme A synthase COG1613 ABC-type sulfate transport system substrate-binding protein COG1614 CO dehydrogenase/acetyl-CoA synthase beta subunit COG1615 uncharacterized membrane protein (UPF0182 family) COG1617 tRNA threonylcarbamoyladenosine modification (KEOPS) complex Cgi121 subunit COG1618 nucleoside-triphosphatase THEP1 COG1619 muramoyltetrapeptide carboxypeptidase LdcA involved in peptidoglycan recycling COG1620 L-lactate permease COG1621 sucrose-6-phosphate hydrolase SacC (GH32 family) COG1622 heme/copper-type cytochrome/quinol oxidase subunit 2 COG1623 DNA integrity scanning protein DisA with diadenylate cyclase activity COG1624 DNA integrity scanning protein DisA with diadenylate cyclase activity COG1625 NifB/MoaA-like Fe-S oxidoreductase COG1626 neutral trehalase COG1627 hypothetical protein COG1628 endonuclease V-like protein UPF0215 family COG1629 outer membrane receptor protein involved in Fe transport COG1630 NurA-like 5'-3' nuclease COG1631 ribosomal protein L44E COG1632 ribosomal protein L15E COG1633 rubrerythrin COG1634 uncharacterized Rossmann fold enzyme COG1635 ribulose 1,5-bisphosphate synthetase/thiazole synthase COG1636 predicted adenine nucleotide alpha hydrolase (AANH) superfamily ATPase COG1637 RecB family endonuclease NucS COG1638 TRAP-type C4-dicarboxylate transport system substrate-binding protein COG1639 HD-like signal output (HDOD) protein COG1640 4-alpha-glucanotransferase COG1641 uncharacterized protein (DUF111 family) COG1643 HrpA-like RNA helicase COG1644 DNA-directed RNA polymerase subunit N (RpoN/RPB10) COG1645 uncharacterized Zn finger protein (UPF0148 family) COG1646 heptaprenylglyceryl phosphate synthase COG1647 esterase/lipase COG1648 siroheme synthase (precorrin-2 oxidase/ferrochelatase) COG1649 uncharacterized lipoprotein YddW (UPF0748 family) COG1650 D-tyrosyl-tRNA(Tyr) deacylase COG1651 protein-disulfide isomerase COG1652 nucleoid-associated protein YgaU COG1653 ABC-type glycerol-3-phosphate transport system substrate-binding protein COG1654 biotin operon repressor COG1655 uncharacterized protein (DUF2225 family) COG1656 uncharacterized protein with PIN domain COG1657 squalene cyclase COG1658 5S rRNA maturation endonuclease (ribonuclease M5) COG1659 uncharacterized linocin/CFP29 family protein COG1660 RNase adaptor protein for sRNA GlmZ degradation COG1661 predicted DNA-binding protein with PD1-like motif COG1662 IS1 family transposase COG1663 tetraacyldisaccharide-1-P 4'-kinase COG1664 cytoskeletal protein CcmA (bactofilin family) COG1665 predicted nucleotidyltransferase COG1666 uncharacterized protein YajQ (UPF0234 family) COG1667 hypothetical protein COG1668 ABC-type Na+ efflux pump permease subunit COG1669 predicted nucleotidyltransferase COG1670 RimJ/RimL family protein N-acetyltransferase COG1671 uncharacterized protein YaiI (UPF0178 family) COG1672 AAA+ ATPase superfamily predicted ATPase COG1673 predicted RNA-binding protein COG1674 DNA segregation ATPase FtsK/SpoIIIE-like protein COG1675 transcription initiation factor IIE alpha subunit COG1676 tRNA splicing endonuclease COG1677 flagellar hook-basal body complex protein FliE COG1678 putative AlgH/UPF0301 family transcriptional regulator COG1679 predicted aconitase COG1680 CubicO group peptidase (beta-lactamase class C family) COG1681 archaellin COG1682 ABC-type polysaccharide/polyol phosphate export permease COG1683 uncharacterized protein YbbK (DUF523 family) COG1684 flagellar biosynthesis protein FliR COG1685 shikimate kinase COG1686 D-alanyl-D-alanine carboxypeptidase COG1687 branched-subunit amino acid transport protein AzlD COG1688 CRISPR/Cas system-associated protein Cas5 (RAMP superfamily) COG1689 hypothetical protein COG1690 RNA-splicing ligase RtcB COG1691 NCAIR mutase (PurE)-related protein COG1692 calcineurin-like phosphoesterase COG1693 repressor of nif and glnA expression COG1694 NTP pyrophosphatase (non-canonical NTP hydrolase) COG1695 DNA-binding PadR family transcriptional regulator COG1696 D-alanyl-lipoteichoic acid acyltransferase DltB (MBOAT superfamily) COG1697 DNA topoisomerase VI subunit A COG1698 uncharacterized protein (UPF0147 family) COG1699 flagellar assembly factor FliW COG1700 predicted component of viral defense system (DUF524 family) COG1701 phosphopantothenate synthetase COG1702 phosphate starvation-inducible protein PhoH COG1703 putative protein kinase ArgK-like GTPase of G3E family COG1704 hypothetical protein COG1705 flagellum-specific peptidoglycan hydrolase FlgJ COG1706 flagellar basal body P-ring protein FlgI COG1707 uncharacterized protein with ACT and thioredoxin-like domain COG1708 predicted nucleotidyltransferase COG1709 predicted transcriptional regulator COG1710 hypothetical protein COG1711 DNA replication initiation complex subunit (GINS family) COG1712 predicted dinucleotide-utilizing enzyme COG1713 HD superfamily phosphohydrolase YqeK COG1714 uncharacterized RDD family membrane protein YckC COG1715 restriction endonuclease Mrr COG1716 pSer/pThr/pTyr-binding forkhead associated (FHA) protein COG1717 ribosomal protein L32E COG1718 serine/threonine-protein kinase RIO1 COG1719 predicted hydrocarbon binding protein COG1720 tRNA (Thr-GGU) A37 N-methylase COG1721 uncharacterized protein (DUF58 family) COG1722 exonuclease VII small subunit COG1723 uncharacterized Rmd1/YagE family protein COG1724 predicted RNA binding protein YcfA (HicA-like mRNA interferase family) COG1725 DNA-binding transcriptional regulator YhcF (GntR family) COG1726 Na+-transporting NADH:ubiquinone oxidoreductase subunit NqrA COG1727 ribosomal protein L18E COG1728 uncharacterized protein YaaR (DUF327 family) COG1729 TolA-binding protein COG1730 prefoldin subunit 5 COG1731 riboflavin synthase COG1732 glycine betaine/choline ABC-type transport system substrate-binding protein COG1733 DNA-binding HxlR family transcriptional regulator COG1734 RNA polymerase-binding transcription factor DksA COG1735 predicted metal-dependent phosphotriesterase family hydrolase COG1736 diphthamide synthase subunit DPH2 COG1737 DNA-binding MurR/RpiR family transcriptional regulator COG1738 uncharacterized PurR-regulated membrane protein YhhQ (DUF165 family) COG1739 putative IMPACT (imprinted ancient) family translation regulator COG1740 Ni,Fe-hydrogenase I small subunit COG1741 redox-sensitive bicupin YhaK (pirin superfamily) COG1742 drug/metabolite transporter superfamily protein YnfA COG1743 adenine-specific DNA methylase COG1744 basic membrane lipoprotein Med (substrate-binding protein (PBP1-ABC) superfamily) COG1745 hypothetical protein COG1746 tRNA nucleotidyltransferase (CCA-adding enzyme) COG1747 transcription elongation factor GreA-like protein COG1748 saccharopine dehydrogenase-like NADP-dependent oxidoreductase COG1749 flagellar hook protein FlgE COG1750 predicted S18 family serine protease COG1751 hypothetical protein COG1752 predicted acylesterase/phospholipase RssA COG1753 predicted CopG family antitoxin COG1754 topoisomerase IA-like protein COG1755 isoprenylcysteine carboxyl methyltransferase (ICMT) family protein YpbQ COG1756 rRNA pseudouridine-1189 N-methylase Emg1 (Nep1/Mra1 family) COG1757 Na+/H+ antiporter NhaC COG1758 DNA-directed RNA polymerase subunit K/omega COG1759 5-formaminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-monophosphate synthetase COG1760 L-serine deaminase COG1761 DNA-directed RNA polymerase subunit L COG1762 mannitol/fructose-specific phosphotransferase system IIA component (Ntr-type) COG1763 molybdopterin-guanine dinucleotide biosynthesis protein COG1764 organic hydroperoxide reductase OsmC/OhrA COG1765 uncharacterized OsmC-like protein COG1766 flagellar biosynthesis/type III secretory pathway M-ring protein FliF/YscJ COG1767 triphosphoribosyl-dephospho-CoA synthetase COG1768 predicted phosphohydrolase COG1769 CRISPR/Cas system CMR-associated protein Cmr3 (group 5 of RAMP superfamily) COG1770 protease II COG1771 Zn-finger domain-containing protein COG1772 hypothetical protein COG1773 rubredoxin COG1774 cell fate regulator YaaT (PSP1 superfamily) COG1775 benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit BcrC/BadD/HgdB COG1776 chemotaxis protein CheY-P-specific phosphatase CheC COG1777 predicted transcriptional regulator COG1778 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase KdsC-like HAD superfamily phosphatase COG1779 C4-type Zn-finger protein COG1780 protein involved in ribonucleotide reduction COG1781 aspartate carbamoyltransferase regulatory subunit COG1782 predicted metal-dependent RNase COG1783 phage terminase large subunit COG1784 TctA family transporter COG1785 alkaline phosphatase COG1786 predicted aconitase with swiveling domain COG1787 HJR/Mrr/RecB family endonuclease COG1788 acyl CoA:acetate/3-ketoacid CoA transferase alpha subunit COG1790 hypothetical protein COG1791 cupin superfamily acireductone dioxygenase involved in methionine salvage COG1792 cell shape-determining protein MreC COG1793 ATP-dependent DNA ligase COG1794 aspartate/glutamate racemase COG1795 formaldehyde-activating enzyme involved in methanogenesis COG1796 DNA polymerase/3'-5' exonuclease PolX COG1797 cobyrinic acid a,c-diamide synthase COG1798 diphthamide biosynthesis methyltransferase COG1799 FtsZ-interacting cell division protein YlmF COG1800 predicted transglutaminase-like protease COG1801 uncharacterized protein YecE (DUF72 family) COG1802 DNA-binding GntR family transcriptional regulator COG1803 methylglyoxal synthase COG1804 crotonobetainyl-CoA:carnitine CoA-transferase CaiB-like acyl-CoA transferase COG1805 Na+-transporting NADH:ubiquinone oxidoreductase subunit NqrB COG1806 regulator of PEP synthase PpsR (kinase-PPPase family) COG1807 4-amino-4-deoxy-L-arabinose transferase-like glycosyltransferase COG1808 uncharacterized membrane protein COG1809 phosphosulfolactate synthase (CoM biosynthesis protein A) COG1810 hypothetical protein COG1811 uncharacterized membrane protein YqgA involved in biofilm formation COG1812 S-adenosylmethionine synthetase COG1813 ribosome-binding protein aMBF1 (putative translation factor) COG1814 VIT1/CCC1 family predicted Fe2+/Mn2+ transporter COG1815 flagellar basal body rod protein FlgB COG1816 adenosine deaminase COG1817 predicted glycosyltransferase COG1818 tRNA(Ser,Leu) C12 N-acetylase TAN1 COG1819 UDP:flavonoid glycosyltransferase YjiC (YdhE family) COG1820 N-acetylglucosamine-6-phosphate deacetylase COG1821 predicted ATP-grasp superfamily ATP-dependent carboligase COG1822 uncharacterized membrane protein COG1823 L-cystine uptake protein TcyP (sodium:dicarboxylate symporter family) COG1824 cation transporter-like permease COG1825 ribosomal protein L25 (general stress protein Ctc) COG1826 Sec-independent protein translocase protein TatA COG1827 transcriptional regulator of NAD metabolism COG1828 phosphoribosylformylglycinamidine (FGAM) synthase PurS component COG1829 pantoate kinase COG1830 DhnA family fructose-bisphosphate aldolase class Ia COG1831 predicted urease superfamily metal-dependent hydrolase COG1832 predicted CoA-binding protein COG1833 Uri superfamily endonuclease COG1834 N-dimethylarginine dimethylaminohydrolase COG1835 peptidoglycan/LPS O-acetylase OafA/YrhL COG1836 uncharacterized membrane protein COG1837 predicted RNA-binding protein YlqC (UPF0109 family) COG1838 tartrate dehydratase beta subunit/fumarate hydratase class I family protein COG1839 adenosine/AMP kinase COG1840 ABC-type Fe3+ transport system substrate-binding protein COG1841 ribosomal protein L30/L7E COG1842 phage shock protein A COG1843 flagellar hook assembly protein FlgD COG1844 hypothetical protein COG1845 heme/copper-type cytochrome/quinol oxidase subunit 3 COG1846 DNA-binding MarR family transcriptional regulator COG1847 predicted RNA-binding protein Jag COG1848 predicted nucleic acid-binding protein COG1849 hypothetical protein COG1850 ribulose 1,5-bisphosphate carboxylase large subunit-like protein COG1851 uncharacterized protein (UPF0128 family) COG1852 hypothetical protein COG1853 flavin reductase (DIM6/NTAB) family NADH-FMN oxidoreductase RutF COG1854 S-ribosylhomocysteine lyase LuxS involved in autoinducer biosynthesis COG1855 predicted PilT family ATPase COG1856 uncharacterized radical SAM superfamily protein COG1857 CRISPR/Cas system-associated protein Cas7 (RAMP superfamily) COG1858 cytochrome c peroxidase COG1859 RNA:NAD 2'-phosphotransferase (TPT1/KptA family) COG1860 uncharacterized protein (UPF0179 family) COG1861 spore coat polysaccharide biosynthesis protein SpsF (cytidylyltransferase family) COG1862 preprotein translocase subunit YajC COG1863 multisubunit Na+/H+ antiporter MnhE subunit COG1864 DNA/RNA endonuclease G (NUC1) COG1865 adenosylcobinamide amidohydrolase COG1866 ATP-dependent phosphoenolpyruvate carboxykinase COG1867 tRNA G26 N,N-dimethylase Trm1 COG1868 flagellar motor switch protein FliM COG1869 D-ribose pyranose/furanose isomerase RbsD COG1871 chemotaxis receptor (MCP) glutamine deamidase CheD COG1872 uncharacterized protein YggU (UPF0235/DUF167 family) COG1873 sporulation protein YlmC with PRC-barrel domain COG1874 beta-galactosidase GanA COG1875 predicted ribonuclease YlaK COG1876 LAS superfamily LD-carboxypeptidase LdcB COG1877 trehalose-6-phosphatase COG1878 kynurenine formamidase COG1879 ABC-type sugar transport system substrate-binding protein COG1880 CO dehydrogenase/acetyl-CoA synthase epsilon subunit COG1881 phosphatidylethanolamine-binding protein (PEBP) family uncharacterized protein COG1882 pyruvate-formate lyase COG1883 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase beta subunit COG1884 methylmalonyl-CoA mutase N-terminal domain/subunit COG1885 uncharacterized protein (UPF0212 family) COG1886 flagellar motor switch/type III secretory pathway protein FliN COG1887 CDP-glycerol glycerophosphotransferase (TagB/SpsB family) COG1888 hypothetical protein COG1889 fibrillarin-like rRNA methylase COG1890 ribosomal protein S3AE COG1891 uncharacterized protein (UPF0264 family) COG1892 phosphoenolpyruvate carboxylase COG1893 ketopantoate reductase COG1894 NADH:ubiquinone oxidoreductase subunit F (NADH-binding) COG1895 uncharacterized protein (UPF0332 family) COG1896 5'-deoxynucleotidase YfbR-like HD superfamily hydrolase COG1897 homoserine trans-succinylase COG1898 dTDP-4-dehydrorhamnose 3,5-epimerase-like enzyme COG1899 deoxyhypusine synthase COG1900 uncharacterized protein (DUF39 family) COG1901 tRNA pseudouridine-54 N-methylase COG1902 2,4-dienoyl-CoA reductase-like NADH-dependent reductase (Old Yellow Enzyme family) COG1903 cobalamin biosynthesis protein CbiD COG1904 glucuronate isomerase COG1905 NADH:ubiquinone oxidoreductase subunit E COG1906 hypothetical protein COG1907 predicted sugar kinase COG1908 coenzyme F420-reducing hydrogenase delta subunit COG1909 uncharacterized protein (UPF0218 family) COG1910 molybdate-binding protein COG1911 ribosomal protein L30E COG1912 S-adenosylmethionine hydrolase COG1913 predicted Zn-dependent protease COG1914 Mn2+/Fe2+ NRAMP family transporter COG1915 hypothetical protein COG1916 pheromone shutdown protein TraB COG1917 quercetin dioxygenase-like cupin family protein COG1918 Fe2+ transport system protein FeoA COG1920 2-phospho-L-lactate guanylyltransferase (CobY/MobA/RfbA family) COG1921 seryl-tRNA(Sec) selenium transferase COG1922 UDP-N-acetyl-D-mannosaminuronic acid transferase (WecB/TagA/CpsF family) COG1923 sRNA-binding regulator protein Hfq COG1924 activator of 2-hydroxyglutaryl-CoA dehydratase COG1925 phosphotransferase system HPr-like phosphotransfer protein COG1926 predicted phosphoribosyltransferase COG1927 F420-dependent methylenetetrahydromethanopterin dehydrogenase COG1928 dolichyl-phosphate-mannose--protein O-mannosyl transferase COG1929 glycerate kinase COG1930 ABC-type cobalt transport system substrate-binding protein COG1931 predicted RNA binding protein with dsRBD fold (UPF0201 family) COG1932 phosphoserine aminotransferase COG1933 DNA polymerase II large subunit COG1934 lipopolysaccharide export system protein LptA COG1935 hypothetical protein COG1936 broad-specificity NMP kinase COG1937 DNA-binding FrmR family transcriptional regulator COG1938 predicted ATP-grasp superfamily ATP-dependent carboligase COG1939 23S rRNA maturation mini-RNase III COG1940 predicted NBD/HSP70 family sugar kinase COG1941 coenzyme F420-reducing hydrogenase gamma subunit COG1942 phenylpyruvate tautomerase PptA (4-oxalocrotonate tautomerase family) COG1943 REP element-mobilizing transposase RayT COG1944 ribosomal protein S12 methylthiotransferase accessory factor YcaO COG1945 pyruvoyl-dependent arginine decarboxylase (PvlArgDC) COG1946 acyl-CoA thioesterase COG1947 4-diphosphocytidyl-2C-methyl-D-erythritol kinase COG1948 ERCC4-type nuclease COG1949 oligoribonuclease (3'-5' exoribonuclease) COG1950 uncharacterized membrane protein YvlD (DUF360 family) COG1951 tartrate dehydratase alpha subunit/fumarate hydratase class I-like protein COG1952 preprotein translocase subunit SecB COG1953 cytosine/uracil/thiamine/allantoin permease COG1954 glycerol-3-phosphate responsive antiterminator COG1955 archaellum biogenesis protein FlaJ (TadC family) COG1956 putative methionine-R-sulfoxide reductase with GAF domain COG1957 inosine-uridine nucleoside N-ribohydrolase COG1958 small nuclear ribonucleoprotein (snRNP)-like protein COG1959 DNA-binding IscR family transcriptional regulator COG1960 alkylation response protein AidB-like acyl-CoA dehydrogenase COG1961 DNA invertase Pin-like site-specific DNA recombinase COG1962 tetrahydromethanopterin S-methyltransferase subunit H COG1963 acid phosphatase family membrane protein YuiD COG1964 uncharacterized radical SAM superfamily Fe-S cluster-containing enzyme COG1965 frataxin-like iron-binding protein CyaY COG1966 carbon starvation protein CstA COG1967 uncharacterized membrane protein COG1968 undecaprenyl pyrophosphate phosphatase UppP COG1969 Ni,Fe-hydrogenase I cytochrome b subunit COG1970 large-conductance mechanosensitive channel COG1971 putative Mn2+ efflux pump MntP COG1972 nucleoside permease NupC COG1973 hydrogenase maturation factor HypE COG1974 SOS-response transcriptional repressor LexA COG1975 xanthine/CO dehydrogenase XdhC/CoxF family maturation factor COG1976 translation initiation factor 6 (eIF-6) COG1977 molybdopterin converting factor small subunit COG1978 predicted RNase H-related nuclease YkuK (DUF458 family) COG1979 alcohol dehydrogenase YqhD (iron-dependent ADH family) COG1980 fructose 1,6-bisphosphatase COG1981 uncharacterized membrane protein COG1982 arginine/lysine/ornithine decarboxylase COG1983 phage shock protein PspC (stress-responsive transcriptional regulator) COG1984 allophanate hydrolase subunit 2 COG1985 riboflavin biosynthesis pyrimidine reductase COG1986 non-canonical (house-cleaning) NTP pyrophosphatase COG1987 flagellar biosynthesis protein FliQ COG1988 membrane-bound metal-dependent hydrolase YbcI (DUF457 family) COG1989 prepilin signal peptidase PulO-like enzyme (type II secretory pathway) COG1990 peptidyl-tRNA hydrolase COG1991 uncharacterized protein (UPF0333 family) COG1992 predicted fused transcriptional regulator/phosphomethylpyrimidine kinase COG1993 PII-like signaling protein COG1994 Zn-dependent protease COG1995 4-hydroxy-L-threonine phosphate dehydrogenase PdxA COG1996 DNA-directed RNA polymerase subunit RPC12/RpoP COG1997 ribosomal protein L37AE/L43A COG1998 ribosomal protein S27AE COG1999 cytochrome oxidase Cu insertion factor (SCO1/SenC/PrrC family) COG2000 uncharacterized Fe-S cluster-containing protein COG2001 DNA-binding transcriptional regulator/RsmH inhibitor MraZ COG2002 bifunctional DNA-binding transcriptional regulator/antitoxin component of YhaV-PrlF toxin-antitoxin module COG2003 DNA repair protein RadC COG2004 ribosomal protein S24E COG2005 molybdenum-dependent DNA-binding transcriptional regulator ModE COG2006 uncharacterized protein (DUF362 family) COG2007 ribosomal protein S8E COG2008 threonine aldolase COG2009 succinate dehydrogenase/fumarate reductase cytochrome b subunit COG2010 mono/diheme cytochrome c family protein COG2011 ABC-type methionine transport system permease subunit COG2012 DNA-directed RNA polymerase subunit H (RpoH/RPB5) COG2013 uncharacterized protein (AIM24 family) COG2014 uncharacterized protein (DUF4213/DUF364 family) COG2015 alkyl sulfatase BDS1-like metallo-beta-lactamase superfamily hydrolase COG2016 predicted ribosome-associated RNA-binding protein Tma20 COG2017 galactose mutarotase-like enzyme COG2018 predicted regulator of Ras-like GTPase activity (Roadblock/LC7/MglB family) COG2019 adenylate kinase COG2020 protein-S-isoprenylcysteine O-methyltransferase Ste14 COG2021 homoserine acetyltransferase COG2022 thiazole synthase ThiGH ThiG subunit COG2023 RNase P subunit RPR2 COG2024 O-phosphoseryl-tRNA(Cys) synthetase COG2025 electron transfer flavoprotein alpha subunit COG2026 mRNA-degrading endonuclease RelE of RelBE toxin-antitoxin system COG2027 D-alanyl-D-alanine carboxypeptidase COG2028 hypothetical protein COG2029 hypothetical protein COG2030 acyl dehydratase COG2031 short subunit fatty acids transporter COG2032 Cu/Zn superoxide dismutase COG2033 desulfoferrodoxin (superoxide reductase-like protein) COG2034 uncharacterized membrane protein COG2035 uncharacterized membrane protein COG2036 histone H3/H4 COG2037 formylmethanofuran:tetrahydromethanopterin formyltransferase COG2038 NaMN:DMB phosphoribosyltransferase COG2039 pyrrolidone-carboxylate peptidase COG2040 S-methylmethionine-dependent homocysteine/selenocysteine methylase COG2041 DMSO/TMAO reductase YedYZ molybdopterin-dependent catalytic subunit COG2042 ribosome biogenesis protein Tsr3 COG2043 uncharacterized protein (DUF169 family) COG2044 predicted peroxiredoxin COG2045 phosphosulfolactate phosphohydrolase-like enzyme COG2046 ATP sulfurylase COG2047 proteasome assembly chaperone (PAC2) family protein COG2048 heterodisulfide reductase subunit B COG2049 allophanate hydrolase subunit 1 COG2050 acyl-coenzyme A thioesterase PaaI-like protein COG2051 ribosomal protein S27E COG2052 regulator of extracellular matrix RemA (YlzA/DUF370 family) COG2053 ribosomal protein S28E/S33 COG2054 aspartokinase-like uncharacterized kinase COG2055 LDH2 family malate/lactate/ureidoglycolate dehydrogenase COG2056 predicted histidine transporter YuiF (NhaC family) COG2057 acyl CoA:acetate/3-ketoacid CoA transferase beta subunit COG2058 ribosomal protein L12E/L44/L45/RPP1/RPP2 COG2059 chromate transport protein ChrA COG2060 K+-transporting ATPase A subunit COG2061 ACT domain-containing protein COG2062 phosphohistidine phosphatase SixA COG2063 flagellar basal body L-ring protein FlgH COG2064 pilus assembly protein TadC COG2065 pyrimidine operon attenuation protein/uracil phosphoribosyltransferase COG2066 glutaminase COG2067 long-subunit fatty acid transport protein COG2068 CTP:molybdopterin cytidylyltransferase MocA COG2069 CO dehydrogenase/acetyl-CoA synthase delta subunit COG2070 NAD(P)H-dependent flavin oxidoreductase YrpB (nitropropane dioxygenase family) COG2071 gamma-glutamyl-gamma-aminobutyrate hydrolase PuuD COG2072 cation diffusion facilitator CzcD-associated flavoprotein CzcO COG2073 cobalamin biosynthesis protein CbiG COG2074 2-phosphoglycerate kinase COG2075 ribosomal protein L24E COG2076 multidrug transporter EmrE-like cation transporter COG2077 peroxiredoxin COG2078 AMMECR1 domain-containing protein COG2079 2-methylcitrate dehydratase PrpD COG2080 aerobic-type carbon monoxide dehydrogenase small subunit (CoxS/CutS family) COG2081 predicted flavoprotein YhiN COG2082 precorrin isomerase COG2083 uncharacterized protein (UPF0216 family) COG2084 3-hydroxyisobutyrate dehydrogenase-like beta-hydroxyacid dehydrogenase COG2085 predicted dinucleotide-binding enzyme COG2086 electron transfer flavoprotein alpha/beta subunit COG2087 adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase COG2088 DNA-binding cell septation regulator SpoVG COG2089 sialic acid synthase SpsE COG2090 hypothetical protein COG2091 phosphopantetheinyl transferase COG2092 translation elongation factor EF-1beta COG2093 RNA polymerase subunit RPABC4/transcription elongation factor Spt4 COG2094 3-methyladenine DNA glycosylase Mpg COG2095 small neutral amino acid transporter SnatA (MarC family) COG2096 cob(I)alamin adenosyltransferase COG2097 ribosomal protein L31E COG2098 hypothetical protein COG2099 precorrin-6x reductase COG2100 uncharacterized Fe-S cluster-containing radical SAM superfamily enzyme COG2101 TATA-box binding protein (TBP) (component of TFIID and TFIIIB) COG2102 diphthamide synthase (EF-2-diphthine--ammonia ligase) COG2103 N-acetylmuramic acid 6-phosphate (MurNAc-6-P) etherase COG2104 sulfur carrier protein ThiS COG2105 gamma-glutamylcyclotransferase (GGCT)/AIG2-like uncharacterized protein YtfP COG2106 predicted SPOUT superfamily RNA methylase MTH1 COG2107 predicted solute-binding protein COG2108 pyruvate formate-lyase activating enzyme-like uncharacterized protein COG2109 ATP:corrinoid adenosyltransferase COG2110 O-acetyl-ADP-ribose deacetylase (regulator of RNase III) COG2111 multisubunit Na+/H+ antiporter MnhB subunit COG2112 predicted Ser/Thr protein kinase COG2113 ABC-type proline/glycine betaine transport system substrate-binding protein COG2114 class 3 adenylate cyclase COG2115 xylose isomerase COG2116 formate/nitrite transporter FocA (FNT family) COG2117 predicted subunit of tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase COG2118 DNA-binding TFAR19-related protein (PDSD5 family) COG2119 putative Ca2+/H+ antiporter (TMEM165/GDT1 family) COG2120 LmbE family N-acetylglucosaminyl deacetylase COG2121 lysophospholipid acyltransferase (LPLAT)-like uncharacterized protein COG2122 ApbE superfamily uncharacterized protein (UPF0280 family) COG2123 exosome complex RNA-binding protein Rrp42 (RNase PH superfamily) COG2124 cytochrome P450 COG2125 ribosomal protein S6E (S10) COG2126 ribosomal protein L37E COG2127 ATP-dependent Clp protease adapter protein ClpS COG2128 alkylhydroperoxidase family enzyme COG2129 Icc-related predicted phosphoesterase COG2130 NADPH-dependent curcumin reductase CurA COG2131 deoxycytidylate deaminase COG2132 FtsP/CotA-like multicopper oxidase with cupredoxin domain COG2133 glucose/arabinose dehydrogenase COG2134 CDP-diacylglycerol pyrophosphatase COG2135 putative SOS response-associated peptidase YedK COG2136 rRNA maturation protein Rpf1 COG2137 SOS response regulatory protein OraA/RecX COG2138 sirohydrochlorin ferrochelatase COG2139 ribosomal protein L21E COG2140 oxalate decarboxylase/phosphoglucose isomerase-like protein (cupin superfamily) COG2141 alkanesulfonate monooxygenase SsuD/methylene tetrahydromethanopterin reductase-like flavin-dependent oxidoreductase (luciferase family) COG2142 succinate dehydrogenase hydrophobic anchor subunit COG2143 thioredoxin-related protein COG2144 selenophosphate synthetase-related protein COG2145 hydroxyethylthiazole kinase-like sugar kinase family protein COG2146 nitrite reductase/ring-hydroxylating ferredoxin subunit COG2147 ribosomal protein L19E COG2148 lipopolysaccharide/colanic/teichoic acid biosynthesis glycosyltransferase COG2149 uncharacterized membrane protein YidH (DUF202 family) COG2150 predicted regulator of amino acid metabolism with ACT domain COG2151 metal-sulfur cluster biosynthetic enzyme COG2152 predicted GH43/DUF377 family glycosyl hydrolase COG2153 predicted GNAT family N-acyltransferase COG2154 pterin-4a-carbinolamine dehydratase COG2155 uncharacterized membrane protein YuzA (DUF378 family) COG2156 K+-transporting ATPase c subunit COG2157 ribosomal protein L20A (L18A) COG2158 Zn-finger protein COG2159 predicted TIM-barrel fold metal-dependent hydrolase COG2160 L-arabinose isomerase COG2161 PHD/YefM family antitoxin component YafN of YafNO toxin-antitoxin module COG2162 arylamine N-acetyltransferase COG2163 ribosomal protein L14E/L6E/L27E COG2164 hypothetical protein COG2165 type II secretory pathway pseudopilin PulG COG2166 sulfur transfer protein SufE COG2167 ribosomal protein L39E COG2168 sulfur transfer complex TusBCD TusB component (DsrH family) COG2169 methylphosphotriester-DNA--protein-cysteine methyltransferase COG2170 gamma-glutamyl:cysteine ligase YbdK (ATP-grasp superfamily) COG2171 tetrahydrodipicolinate N-succinyltransferase COG2172 anti-sigma regulatory factor (Ser/Thr protein kinase) COG2173 D-alanyl-D-alanine dipeptidase COG2174 ribosomal protein L34E COG2175 alpha-ketoglutarate-dependent taurine dioxygenase COG2176 DNA polymerase III alpha subunit (gram-positive type) COG2177 cell division protein FtsX COG2178 predicted translin family RNA/ssDNA-binding protein COG2179 predicted HAD superfamily phosphohydrolase YqeG COG2180 nitrate reductase assembly molybdenum cofactor insertion protein NarJ COG2181 nitrate reductase gamma subunit COG2182 maltose-binding protein MalE COG2183 transcriptional accessory protein Tex/SPT6 COG2184 fido (protein-threonine AMPylation protein) COG2185 methylmalonyl-CoA mutase cobalamin-binding subunit COG2186 DNA-binding FadR family transcriptional regulator COG2187 aminoglycoside phosphotransferase family enzyme COG2188 DNA-binding GntR family transcriptional regulator COG2189 adenine specific DNA methylase Mod COG2190 phosphotransferase system IIA component COG2191 formylmethanofuran dehydrogenase subunit E COG2192 predicted NodU family carbamoyl transferase COG2193 bacterioferritin (cytochrome b1) COG2194 glucan phosphoethanolaminetransferase (alkaline phosphatase superfamily) COG2195 di/tripeptidase COG2197 DNA-binding NarL/FixJ family response regulator COG2198 HPt (histidine-containing phosphotransfer) domain-containing protein COG2199 GGDEF domain-containing protein COG2200 EAL domain-containing protein (putative c-di-GMP-specific phosphodiesterase class I) COG2201 chemotaxis response regulator CheB COG2202 PAS domain-containing protein COG2203 GAF domain-containing protein COG2204 DNA-binding NtrC family response regulator COG2205 K+-sensing histidine kinase KdpD COG2206 HD-GYP domain-containing protein (c-di-GMP phosphodiesterase class II) COG2207 AraC-like DNA-binding protein COG2208 serine phosphatase RsbU (regulator of sigma subunit) COG2209 Na+-transporting NADH:ubiquinone oxidoreductase subunit NqrE COG2210 peroxiredoxin family protein COG2211 Na+/melibiose symporter-like transporter COG2212 multisubunit Na+/H+ antiporter MnhF subunit COG2213 mannitol-specific phosphotransferase system IIBC component COG2214 curved DNA-binding protein CbpA COG2215 ABC-type nickel/cobalt efflux system permease component RcnA COG2216 high-affinity K+ transport system ATPase subunit B COG2217 cation transport ATPase COG2218 formylmethanofuran dehydrogenase subunit C COG2219 DNA primase large subunit COG2220 L-ascorbate metabolism protein UlaG (beta-lactamase superfamily) COG2221 dissimilatory sulfite reductase (desulfoviridin) alpha/beta subunit COG2222 fructoselysine-6-P-deglycase FrlB-like protein COG2223 nitrate/nitrite transporter NarK COG2224 isocitrate lyase COG2225 malate synthase COG2226 ubiquinone/menaquinone biosynthesis C-methylase UbiE COG2227 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase COG2229 signal recognition particle receptor subunit beta COG2230 cyclopropane fatty-acyl-phospholipid synthase-like methyltransferase COG2231 endonuclease III-like uncharacterized protein COG2232 predicted ATP-grasp superfamily ATP-dependent carboligase COG2233 xanthine/uracil permease COG2234 Zn-dependent M28 family amino/carboxypeptidase COG2235 arginine deiminase COG2236 hypoxanthine phosphoribosyltransferase COG2237 uncharacterized membrane protein COG2238 ribosomal protein S19E (S16A) COG2239 Mg/Co/Ni transporter MgtE COG2240 pyridoxal/pyridoxine/pyridoxamine kinase COG2241 precorrin-6B methylase 1 COG2242 precorrin-6B methylase 2 COG2243 precorrin-2 methylase COG2244 O-antigen/teichoic acid export membrane protein COG2245 uncharacterized membrane protein COG2246 putative flippase GtrA COG2247 putative cell wall-binding protein COG2248 predicted metallo-beta-lactamase superfamily hydrolase COG2249 putative NADPH-quinone reductase COG2250 HEPN domain-containing protein COG2251 predicted RecB family nuclease COG2252 xanthine/uracil/vitamin C permease (AzgA family) COG2253 predicted nucleotidyltransferase component of viral defense system COG2254 CRISPR/Cas system-associated endonuclease Cas3-HD COG2255 Holliday junction resolvasome RuvABC ATP-dependent DNA helicase subunit COG2256 replication-associated recombination protein RarA COG2257 type III secretion system FlhB-like substrate exporter COG2258 MOSC domain-containing protein YiiM COG2259 uncharacterized membrane protein YphA (DoxX/SURF4 family) COG2260 rRNA maturation protein Nop10 COG2261 uncharacterized membrane protein YeaQ/YmgE (transglycosylase-associated protein family) COG2262 50S ribosomal subunit-associated GTPase HflX COG2263 predicted RNA methylase COG2264 ribosomal protein L11 methylase PrmA COG2265 tRNA/tmRNA/rRNA uracil-C5-methylase (TrmA/RlmC/RlmD family) COG2266 GTP:adenosylcobinamide-phosphate guanylyltransferase COG2267 alpha-beta hydrolase superfamily lysophospholipase COG2268 uncharacterized membrane protein YqiK COG2269 elongation factor P--beta-lysine ligase COG2270 MFS-type transporter involved in bile tolerance (Atg22 family) COG2271 sugar phosphate permease COG2272 carboxylesterase type B COG2273 beta-glucanase (GH16 family) COG2274 ABC-type bacteriocin/lantibiotic exporter with double-glycine peptidase domain COG2301 citrate lyase beta subunit COG2302 RNA-binding protein YlmH COG2303 choline dehydrogenase-like flavoprotein COG2304 secreted protein with Ig-like and vWFA domain COG2306 predicted RNA-binding protein associated with RNAse of E/G family COG2307 uncharacterized alpha-E superfamily protein COG2308 uncharacterized circularly permuted ATP-grasp superfamily protein COG2309 leucyl aminopeptidase (aminopeptidase T) COG2310 stress response protein SCP2 COG2311 uncharacterized membrane protein YeiB COG2312 erythromycin esterase-like protein COG2313 pseudouridine-5'-phosphate glycosidase COG2314 TM2 domain-containing membrane protein YozV COG2315 predicted DNA-binding protein (MmcQ/YjbR family) COG2316 predicted hydrolase (HD superfamily) COG2317 Zn-dependent M32 family carboxypeptidase COG2318 uncharacterized damage-inducible protein DinB COG2319 WD40 repeat protein COG2320 GrpB-like predicted nucleotidyltransferase (UPF0157 family) COG2321 predicted metalloprotease COG2322 uncharacterized membrane protein YozB (DUF420 family) COG2323 uncharacterized membrane protein YcaP (DUF421 family) COG2324 uncharacterized membrane protein COG2326 polyphosphate kinase 2 (PPK2 family) COG2327 polysaccharide pyruvyl transferase WcaK-like protein COG2329 heme-degrading monooxygenase HmoA COG2331 predicted nucleic acid-binding Zn ribbon protein COG2332 cytochrome c-type biogenesis protein CcmE COG2333 beta-lactamase superfamily II metal-dependent hydrolase COG2334 Ser/Thr protein kinase RdoA (MazF antagonist) COG2335 uncharacterized surface protein with fasciclin (FAS1) repeats COG2336 antitoxin component of MazEF toxin-antitoxin module COG2337 mRNA-degrading endonuclease toxin of MazEF toxin-antitoxin module COG2339 RsiW-degrading membrane proteinase PrsW (M82 family) COG2340 uncharacterized protein YkwD COG2342 endo-alpha-1,4-polygalactosaminidase (GH114 family) COG2343 uncharacterized protein (DUF427 family) COG2344 NADH/NAD ratio-sensing transcriptional regulator Rex COG2345 predicted ArsR family transcriptional regulator COG2346 truncated hemoglobin YjbI COG2348 lipid II:glycine glycyltransferase (peptidoglycan interpeptide bridge formation enzyme) COG2350 uncharacterized protein YciI COG2351 5-hydroxyisourate hydrolase-like protein (transthyretin family) COG2352 phosphoenolpyruvate carboxylase COG2353 polyisoprenoid-binding protein YceI COG2354 predicted DNA repair protein MutK COG2355 microsomal dipeptidase-like Zn-dependent dipeptidase COG2356 endonuclease I COG2357 ppGpp synthetase/RelA/SpoT-type nucleotidyltranferase COG2358 TRAP-type uncharacterized transport system substrate-binding protein COG2359 stage V sporulation protein SpoVS COG2360 Leu/Phe-tRNA-protein transferase COG2361 uncharacterized protein with HEPN domain COG2362 D-aminopeptidase COG2363 uncharacterized membrane protein YgdD (TMEM256/DUF423 family) COG2364 uncharacterized membrane protein YczE COG2365 protein tyrosine/serine phosphatase COG2366 acyl-homoserine lactone acylase PvdQ COG2367 beta-lactamase class A COG2368 aromatic ring hydroxylase COG2369 uncharacterized protein with gpF-like domain COG2370 hydrogenase/urease accessory protein HupE COG2371 urease accessory protein UreE COG2372 methionine-rich copper-binding protein CopC COG2373 uncharacterized protein YfaS (alpha-2-macroglobulin family) COG2374 predicted extracellular nuclease COG2375 NADPH-dependent ferric siderophore reductase COG2376 dihydroxyacetone kinase COG2377 1,6-anhydro-N-acetylmuramate kinase COG2378 predicted DNA-binding transcriptional regulator YafY COG2379 glycerate-2-kinase COG2380 hypothetical protein COG2382 enterochelin esterase-like enzyme COG2383 uncharacterized membrane protein (Fun14 family) COG2384 tRNA A22 N-methylase COG2385 peptidoglycan hydrolase-like amidase COG2386 ABC-type transport system involved in cytochrome c biogenesis permease component COG2388 predicted GNAT family acetyltransferase COG2389 uncharacterized metal-binding protein COG2390 DNA-binding transcriptional regulator LsrR (DeoR family) COG2391 uncharacterized membrane protein YedE/YeeE COG2401 ABC-type ATPase with predicted acetyltransferase domain COG2402 predicted nucleic acid-binding protein COG2403 predicted GTPase COG2404 oligoribonuclease NrnB/cAMP/cGMP phosphodiesterase (DHH superfamily) COG2405 predicted nucleic acid-binding protein COG2406 ferritin-like protein COG2407 L-fucose isomerase-like protein COG2409 uncharacterized membrane protein YdfJ with MMPL/SSD domain COG2410 predicted nuclease with RNAse H fold COG2411 hypothetical protein COG2412 hypothetical protein COG2413 predicted nucleotidyltransferase COG2414 aldehyde:ferredoxin oxidoreductase COG2419 Trm5-related predicted tRNA methylase COG2421 acetamidase/formamidase COG2423 ornithine cyclodeaminase/alanine dehydrogenase-like protein (mu-crystallin family) COG2425 uncharacterized protein with von Willebrand factor type A (vWA) domain COG2426 uncharacterized membrane protein COG2427 uncharacterized protein YjgD (DUF1641 family) COG2428 ribosome biogenesis SPOUT family RNA methylase Rps3 COG2429 GTP cyclohydrolase III COG2430 hypothetical protein COG2431 uncharacterized membrane protein YbjE (DUF340 family) COG2433 predicted RNase H-like nuclease (RuvC/YqgF family) COG2440 ferredoxin-like protein FixX COG2441 predicted butyrate kinase (DUF1464 family) COG2442 uncharacterized protein (DUF433 family) COG2443 preprotein translocase subunit Sss1 COG2445 uncharacterized protein YutE (UPF0331/DUF86 family) COG2450 SepF-like predicted cell division protein (DUF552 family) COG2451 ribosomal protein L35AE/L33A COG2452 predicted site-specific integrase-resolvase COG2453 protein-tyrosine phosphatase COG2454 hypothetical protein COG2456 hypothetical protein COG2457 hypothetical protein COG2461 DUF438 domain-containing protein COG2469 helix-turn-helix protein COG2501 ribosome-associated protein YbcJ (S4-like RNA binding protein) COG2502 asparagine synthetase A COG2503 predicted secreted acid phosphatase COG2508 DNA-binding PucR family transcriptional regulator COG2509 uncharacterized FAD-dependent dehydrogenase COG2510 uncharacterized membrane protein COG2511 Glu-tRNA(Gln) amidotransferase subunit E-like FAD-binding protein COG2512 uncharacterized membrane protein COG2513 2-methylisocitrate lyase-like PEP mutase family enzyme COG2514 catechol-2,3-dioxygenase COG2515 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase-like pyridoxal-dependent ACC family enzyme COG2516 biotin synthase-related radical SAM superfamily protein COG2517 predicted RNA-binding protein with EMAP domain COG2518 protein-L-isoaspartate O-methyltransferase COG2519 tRNA A58 N-methylase Trm61 COG2520 tRNA G37 N-methylase Trm5 COG2521 predicted methyltransferase COG2522 predicted transcriptional regulator COG2524 predicted transcriptional regulator COG2602 beta-lactamase class D COG2603 tRNA 2-selenouridine synthase SelU COG2604 hypothetical protein COG2605 galactokinase/mevalonate kinase-like predicted kinase COG2606 prolyl-tRNA editing enzyme YbaK/EbsC (Cys-tRNA(Pro) deacylase) COG2607 predicted AAA+ superfamily ATPase COG2608 copper chaperone CopZ COG2609 pyruvate dehydrogenase complex dehydrogenase (E1) component COG2610 H+/gluconate symporter-like permease COG2703 hemerythrin COG2704 anaerobic C4-dicarboxylate transporter COG2706 6-phosphogluconolactonase (cycloisomerase 2 family) COG2707 uncharacterized membrane protein (DUF441 family) COG2710 nitrogenase molybdenum-iron protein alpha/beta subunit COG2715 spore maturation protein SpmA COG2716 glycine cleavage system regulatory protein COG2717 DMSO/TMAO reductase YedYZ heme-binding membrane subunit COG2718 uncharacterized sporulation protein YeaH/YhbH (DUF444 family) COG2719 spore cortex formation protein SpoVR/YcgB (stage V sporulation) COG2720 vancomycin resistance protein YoaR COG2721 altronate dehydratase COG2723 beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase COG2730 aryl-phospho-beta-D-glucosidase BglC (GH1 family) COG2731 beta-galactosidase beta subunit COG2732 RNAse (barnase) inhibitor barstar COG2733 uncharacterized membrane-anchored protein YjiN (DUF445 family) COG2738 Zn-dependent membrane protease YugP COG2739 predicted DNA-binding protein YlxM (UPF0122 family) COG2740 predicted RNA-binding protein YlxR (DUF448 family) COG2746 aminoglycoside N3'-acetyltransferase COG2747 anti-sigma28 factor (negative regulator of flagellin synthesis) COG2755 lysophospholipase L1-like esterase COG2759 formyltetrahydrofolate synthetase COG2761 predicted DsbA family dithiol-disulfide isomerase COG2764 uncharacterized glyoxalase superfamily protein PhnB COG2766 predicted Ser/Thr protein kinase COG2768 uncharacterized Fe-S center protein COG2770 HAMP domain-containing protein COG2771 DNA-binding CsgD family transcriptional regulator COG2801 transposase InsO family protein COG2802 Lon protease-like protein COG2804 type II secretory ATPase GspE/PulE/Tfp pilus assembly ATPase PilB-like protein COG2805 Tfp pilus assembly pilus retraction ATPase PilT COG2807 cyanate permease COG2808 predicted FMN-binding regulatory protein PaiB COG2810 predicted type IV restriction endonuclease COG2811 vacuolar-type H+-ATPase subunit H COG2812 DNA polymerase III gamma/tau subunit COG2813 16S rRNA G1207 methylase RsmC COG2814 predicted MFS family arabinose efflux permease COG2815 beta-lactam-binding protein with PASTA domain COG2816 NADH pyrophosphatase NudC (nudix superfamily) COG2818 3-methyladenine DNA glycosylase Tag COG2819 predicted alpha/beta superfamily hydrolase COG2820 uridine phosphorylase COG2821 membrane-bound lytic murein transglycosylase COG2822 iron uptake system EfeUOB component EfeO/EfeM COG2823 osmotically-inducible protein OsmY COG2824 uncharacterized Zn ribbon protein COG2825 Skp family chaperone for outer membrane proteins COG2826 IS30 family transposase COG2827 predicted GIY-YIG superfamily endonuclease COG2828 2-methylaconitate cis-trans-isomerase PrpF COG2829 outer membrane phospholipase A COG2830 hypothetical protein COG2831 hemolysin activation/secretion protein COG2832 uncharacterized membrane protein YbaN (DUF454 family) COG2833 uncharacterized ferritin-like protein (DUF455 family) COG2834 outer membrane lipoprotein-sorting protein COG2835 uncharacterized protein YbaR (Trm112 family) COG2836 sulfite exporter TauE/SafE COG2837 deferrochelatase/peroxidase EfeB COG2838 monomeric isocitrate dehydrogenase COG2839 uncharacterized protein YqgC (DUF456 family) COG2840 DNA-nicking Smr family endonuclease COG2841 uncharacterized protein YdcH (DUF465 family) COG2842 DNA transposition AAA+ family ATPase COG2843 poly-gamma-glutamate capsule biosynthesis protein CapA/YwtB (metallophosphatase superfamily) COG2844 UTP:GlnB (protein PII) uridylyltransferase COG2845 hypothetical protein COG2846 iron-sulfur cluster repair protein YtfE (RIC family) COG2847 copper(I)-binding protein COG2848 uncharacterized protein (UPF0210 family) COG2849 antitoxin component YwqK of YwqJK toxin-antitoxin module COG2850 ribosomal protein L16 Arg81 hydroxylase COG2851 Mg2+/citrate symporter COG2852 very-short-patch-repair endonuclease COG2853 ABC-type transporter lipoprotein component MlaA COG2854 ABC-type transporter MlaC component COG2855 uncharacterized membrane protein YadS COG2856 Zn-dependent peptidase ImmA (M78 family) COG2857 cytochrome c1 COG2859 hypothetical protein COG2860 uncharacterized membrane protein YeiH COG2861 polysaccharide deacetylase 2 family uncharacterized protein YibQ COG2862 uncharacterized membrane protein YqhA COG2863 cytochrome c553 COG2864 cytochrome b subunit of formate dehydrogenase COG2865 predicted HTH transcriptional regulator COG2866 murein tripeptide amidase MpaA COG2867 ribosome-associated toxin RatA of RatAB toxin-antitoxin module COG2868 uncharacterized protein YsxB (DUF464 family) COG2869 Na+-transporting NADH:ubiquinone oxidoreductase subunit NqrC COG2870 bifunctional ADP-heptose synthase (sugar kinase/adenylyltransferase) COG2871 Na+-transporting NADH:ubiquinone oxidoreductase subunit NqrF COG2872 Ser-tRNA(Ala) deacylase AlaX COG2873 O-acetylhomoserine/O-acetylserine sulfhydrylase-like pyridoxal-dependent enzyme COG2874 archaellum biogenesis ATPase FlaH COG2875 precorrin-4 methylase COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase COG2878 Na+-translocating ferredoxin:NAD+ oxidoreductase RNF subunit RnfB COG2879 uncharacterized short protein YbdD (DUF466 family) COG2880 predicted DNA-binding antitoxin AbrB/MazE fold protein COG2881 hypothetical protein COG2882 flagellar biosynthesis chaperone FliJ COG2884 ABC-type ATPase involved in cell division COG2885 outer membrane protein OmpA-like peptidoglycan-associated protein COG2886 predicted HTH domain antitoxin COG2887 RecB family exonuclease COG2888 predicted RNA-binding Zn-ribbon protein involved in translation (DUF1610 family) COG2890 methylase of polypeptide subunit release factors COG2891 cell shape-determining protein MreD COG2892 tRNA threonylcarbamoyladenosine modification (KEOPS) complex Pcc1 subunit COG2893 mannose/fructose-specific phosphotransferase system component IIA COG2894 septum formation inhibitor-activating ATPase MinD COG2895 sulfate adenylyltransferase subunit 1 (EFTu-like GTPase family) COG2896 molybdenum cofactor biosynthesis enzyme MoaA COG2897 3-mercaptopyruvate sulfurtransferase SseA COG2898 lysylphosphatidylglycerol synthetase-like protein (DUF2156 family) COG2899 hypothetical protein COG2900 uncharacterized coiled-coil protein SlyX COG2901 DNA-binding protein Fis COG2902 NAD-specific glutamate dehydrogenase COG2904 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF-like protein COG2905 signal-transduction protein with cAMP-binding, CBS, and nucleotidyltransferase domain COG2906 bacterioferritin-associated ferredoxin COG2907 predicted NAD/FAD-binding protein COG2908 UDP-2,3-diacylglucosamine pyrophosphatase LpxH COG2909 ATP/maltotriose-dependent transcriptional regulator MalT COG2910 putative NADH-flavin reductase COG2911 autotransporter translocation and assembly factor TamB COG2912 regulator of sirC expression with transglutaminase-like and TPR domain COG2913 outer membrane protein assembly factor BamE (lipoprotein component of BamABCDE complex) COG2914 putative ubiquitin-RnfH superfamily antitoxin RatB of RatAB toxin-antitoxin module COG2915 CII-binding regulator of phage lambda lysogenization HflD COG2916 DNA-binding protein H-NS COG2917 intracellular septation protein A COG2918 gamma-glutamylcysteine synthetase COG2919 cell division protein FtsB COG2920 sulfur relay (sulfurtransferase) DsrC/TusE family protein COG2921 putative lipoic acid-binding regulatory protein COG2922 uncharacterized protein Smg (DUF494 family) COG2923 sulfur relay (sulfurtransferase) DsrF/TusC family protein COG2924 Fe-S cluster biosynthesis and repair protein YggX COG2925 exonuclease I COG2926 uncharacterized protein YeeX (DUF496 family) COG2927 DNA polymerase IIIc chi subunit COG2928 uncharacterized membrane protein COG2929 uncharacterized DUF497 family protein COG2930 lipid-binding SYLF domain-containing protein COG2931 Ca2+-binding RTX toxin-like protein COG2932 phage repressor protein C with HTH and peptisase S24 domain COG2933 23S rRNA C2498 (ribose-2'-O)-methylase RlmM COG2935 arginyl-tRNA--protein-N-Asp/Glu arginylyltransferase COG2936 predicted acyl esterase COG2937 glycerol-3-phosphate O-acyltransferase COG2938 succinate dehydrogenase flavin-adding protein (antitoxin of CptAB toxin-antitoxin module) COG2939 carboxypeptidase C (cathepsin A) COG2940 SET domain-containing protein COG2941 demethoxyubiquinone hydroxylase (CLK1/Coq7/Cat5 family) COG2942 mannose/cellobiose epimerase-like protein (N-acyl-D-glucosamine 2-epimerase family) COG2943 membrane glycosyltransferase COG2944 DNA-binding transcriptional regulator YiaG COG2945 alpha/beta superfamily hydrolase COG2946 DNA relaxase NicK COG2947 predicted RNA-binding protein with PUA-like domain COG2948 type IV secretory pathway VirB10-like protein COG2949 vancomycin permeability regulator SanA COG2951 membrane-bound lytic murein transglycosylase B COG2952 hypothetical protein COG2954 CYTH domain-containing protein COG2956 lipopolysaccharide biosynthesis regulator YciM COG2957 agmatine/peptidylarginine deiminase COG2958 hypothetical protein COG2959 uncharacterized protein HemX COG2960 BMFP domain-containing protein YqiC COG2961 23S rRNA A2030 N6-methylase RlmJ COG2962 EamA domain-containing membrane protein RarD COG2963 transposase-like protein COG2964 predicted transcriptional regulator YheO COG2965 primosomal replication protein N COG2966 uncharacterized membrane protein YjjP (DUF1212 family) COG2967 uncharacterized protein affecting Mg2+/Co2+ transport COG2968 uncharacterized protein YggE COG2969 stringent starvation protein B COG2971 N-acetylglucosamine kinase-like BadF-type ATPase COG2972 sensor histidine kinase YesM COG2973 Trp operon repressor COG2974 DNA recombination-dependent growth factor C COG2975 Fe-S-cluster formation regulator IscX/YfhJ COG2976 predicted negative regulator of RcsB-dependent stress response COG2977 4'-phosphopantetheinyl transferase EntD COG2978 p-aminobenzoyl-glutamate transporter AbgT COG2979 uncharacterized membrane protein YebE (DUF533 family) COG2980 outer membrane lipopolysaccharide assembly protein LptE/RlpB COG2981 uncharacterized protein involved in cysteine biosynthesis COG2982 uncharacterized protein involved in outer membrane biogenesis COG2983 uncharacterized cysteine cluster protein YcgN (CxxCxxCC family) COG2984 ABC-type uncharacterized transport system substrate-binding protein COG2985 uncharacterized transporter YbjL COG2986 histidine ammonia-lyase COG2987 urocanate hydratase COG2988 succinylglutamate desuccinylase COG2989 murein L,D-transpeptidase YcbB/YkuD COG2990 uncharacterized protein VirK/YbjX COG2991 hypothetical protein COG2992 uncharacterized FlgJ-related protein COG2993 cbb3-type cytochrome oxidase cytochrome c subunit COG2994 hemolysin-activating ACP:hemolysin acyltransferase COG2995 uncharacterized paraquat-inducible protein A COG2996 predicted RNA-binding protein (virulence factor B family) COG2998 ABC-type tungstate transport system permease subunit COG2999 glutaredoxin 2 COG3000 sterol desaturase/sphingolipid hydroxylase (fatty acid hydroxylase superfamily) COG3001 fructosamine-3-kinase COG3002 uncharacterized protein YbcC (UPF0753/DUF2309 family) COG3004 Na+/H+ antiporter NhaA COG3005 nitrate/TMAO reductase-like tetraheme cytochrome c subunit COG3006 chromosome condensin MukBEF complex kleisin-like MukF subunit COG3007 trans-2-enoyl-CoA reductase COG3008 paraquat-inducible protein B COG3009 uncharacterized lipoprotein YmbA COG3010 putative N-acetylmannosamine-6-phosphate epimerase COG3011 predicted DCC family thiol-disulfide oxidoreductase YuxK COG3012 uncharacterized protein YchJ COG3013 uncharacterized protein YfbU (UPF0304 family) COG3014 hypothetical protein COG3015 uncharacterized lipoprotein NlpE involved in copper resistance COG3016 uncharacterized iron-regulated protein COG3017 outer membrane biogenesis lipoprotein LolB COG3018 hypothetical protein COG3019 hypothetical protein COG3021 endonuclease/exonuclease/phosphatase (EEP) superfamily protein YafD COG3022 cytoplasmic iron level regulating protein YaaA (DUF328/UPF0246 family) COG3023 N-acetyl-anhydromuramyl-L-alanine amidase AmpD COG3024 endogenous inhibitor of DNA gyrase (YacG/DUF329 family) COG3025 inorganic triphosphatase YgiF COG3026 negative regulator of sigma E activity COG3027 cell division protein ZapA (FtsZ GTPase activity inhibitor) COG3028 ribosomal 50S subunit-associated protein YjgA (DUF615 family) COG3029 fumarate reductase subunit C COG3030 UPF0716 family protein affecting phage T7 exclusion COG3031 type II secretory pathway component PulC COG3033 tryptophanase COG3034 murein L,D-transpeptidase YafK COG3036 stalled ribosome alternative rescue factor ArfA COG3037 ascorbate-specific PTS system EIIC-type component UlaA COG3038 cytochrome b561 COG3039 IS5 family transposase COG3040 lipocalin COG3041 mRNA-degrading endonuclease YafQ of YafQ-DinJ toxin-antitoxin module COG3042 putative hemolysin COG3043 nitrate reductase cytochrome c-type subunit COG3044 predicted ABC-class ATPase COG3045 catabolite regulation protein CreA COG3046 deoxyribodipyrimidine photolyase-like uncharacterized protein COG3047 outer membrane protein W COG3048 D-serine dehydratase COG3049 penicillin V acylase-like amidase (Ntn superfamily) COG3050 DNA polymerase III psi subunit COG3051 citrate lyase alpha subunit COG3052 citrate lyase gamma subunit COG3053 citrate lyase synthetase COG3054 predicted transcriptional regulator COG3055 N-acetylneuraminic acid mutarotase COG3056 uncharacterized lipoprotein YajG COG3057 negative regulator of replication initiation COG3058 formate dehydrogenase maturation protein FdhE COG3059 uncharacterized membrane protein YkgB COG3060 transcriptional regulator of met regulon COG3061 cell envelope opacity-associated protein A COG3062 nitrate reductase NapAB chaperone NapD COG3063 Tfp pilus assembly protein PilF COG3064 membrane protein involved in colicin uptake COG3065 starvation-inducible outer membrane lipoprotein COG3066 DNA mismatch repair protein MutH COG3067 Na+/H+ antiporter NhaB COG3068 uncharacterized protein YjaG (DUF416 family) COG3069 C4-dicarboxylate transporter COG3070 TfoX/Sxy family transcriptional regulator of competence genes COG3071 uncharacterized protein HemY COG3072 adenylate cyclase COG3073 negative regulator of sigma E activity COG3074 FtsZ-binding cell division protein ZapB COG3075 anaerobic glycerol-3-phosphate dehydrogenase COG3076 regulator of RNase E activity RraB COG3077 antitoxin component of RelBE/YafQ-DinJ toxin-antitoxin module COG3078 ribosome assembly protein YihI (activator of Der GTPase) COG3079 uncharacterized protein YgfB (UPF0149 family) COG3080 fumarate reductase subunit D COG3081 nucleoid-associated protein YejK COG3082 uncharacterized protein YejL (UPF0352 family) COG3083 membrane-anchored protein YejM (alkaline phosphatase superfamily) COG3084 uncharacterized protein YihD (DUF1040 family) COG3085 uncharacterized protein YifE (UPF0438 family) COG3086 positive regulator of sigma E activity COG3087 cell division protein FtsN COG3088 cytochrome c-type biogenesis protein CcmH/NrfF COG3089 uncharacterized protein YheU (UPF0270 family) COG3090 TRAP-type C4-dicarboxylate transport system permease small subunit COG3091 predicted SprT family Zn-dependent metalloprotease COG3092 uncharacterized membrane protein YfbV (UPF0208 family) COG3093 plasmid maintenance system antidote protein VapI COG3094 uncharacterized membrane protein SirB2 COG3095 chromosome condensin MukBEF MukE localization factor COG3096 chromosome condensin MukBEF ATPase and DNA-binding subunit MukB COG3097 uncharacterized protein YqfB (UPF0267 family) COG3098 uncharacterized protein YqcC (DUF446 family) COG3099 uncharacterized protein YciU (UPF0263 family) COG3100 uncharacterized protein YcgL (UPF0745 family) COG3101 elongation factor P hydroxylase COG3102 predicted metalloenzyme YecM COG3103 uncharacterized protein YgiM (DUF1202 family) COG3104 dipeptide/tripeptide permease COG3105 uncharacterized membrane-anchored protein YhcB (DUF1043 family) COG3106 predicted YcjX-like family ATPase COG3107 outer membrane PBP1 activator LpoA protein COG3108 uncharacterized protein YcbK (DUF882 family) COG3109 sRNA-binding protein COG3110 uncharacterized protein YccT (UPF0319 family) COG3111 uncharacterized protein YdeI (BOF family) COG3112 uncharacterized protein YacL (UPF0231 family) COG3113 ABC-type transporter Mla MlaB component COG3114 heme exporter protein D COG3115 FtsZ-interacting cell division protein ZipA COG3116 cell division protein FtsL COG3117 lipopolysaccharide export system protein LptC COG3118 thioredoxin-like negative regulator of GroEL COG3119 arylsulfatase A-like enzyme COG3120 macrodomain Ter protein organizer (MatP/YcbG family) COG3121 P pilus assembly chaperone PapD COG3122 uncharacterized protein YaiL (DUF2058 family) COG3123 uncharacterized protein YaiE (UPF0345 family) COG3124 acyl carrier protein phosphodiesterase COG3125 heme/copper-type cytochrome/quinol oxidase subunit 4 COG3126 uncharacterized lipoprotein YbaY COG3127 predicted lysophospholipase L1 biosynthesis ABC-type transport system permease subunit COG3128 predicted 2-oxoglutarate/Fe(II)-dependent dioxygenase YbiX COG3129 23S rRNA A1618 N6-methylase RlmF COG3130 ribosome modulation factor COG3131 glucan biosynthesis protein COG3132 uncharacterized protein YceH (UPF0502 family) COG3133 outer membrane lipoprotein SlyB COG3134 uncharacterized protein YcfJ COG3135 predicted benzoate:H+ symporter BenE COG3136 uncharacterized membrane protein (GlpM family) COG3137 putative salt-induced outer membrane protein YdiY COG3138 arginine/ornithine N-succinyltransferase beta subunit COG3139 uncharacterized protein YeaC (DUF1315 family) COG3140 uncharacterized protein YoaH (UPF0181 family) COG3141 dsDNA-binding SOS-regulon protein COG3142 copper homeostasis protein CutC COG3143 chemotaxis regulatin CheY-phosphate phosphatase CheZ COG3144 flagellar hook-length control protein FliK COG3145 alkylated DNA repair dioxygenase AlkB COG3146 predicted N-acyltransferase COG3147 cell division septation protein DedD COG3148 DTW domain-containing protein YfiP COG3149 type II secretory pathway component PulM COG3150 predicted esterase YcpF (UPF0227 family) COG3151 uncharacterized protein YqiB (DUF1249 family) COG3152 uncharacterized membrane protein YhaH (DUF805 family) COG3153 predicted N-acetyltransferase YhbS COG3154 predicted lipid carrier protein YhbT COG3155 enhancing lycopene biosynthesis protein 2 COG3156 type II secretory pathway component PulK COG3157 type VI protein secretion system component Hcp COG3158 K+ transporter COG3159 uncharacterized protein YigA (DUF484 family) COG3160 regulator of sigma D COG3161 chorismate-pyruvate lyase COG3162 uncharacterized membrane protein (DUF485 family) COG3164 uncharacterized protein YhdP COG3165 ubiquinone biosynthesis protein UbiJ COG3166 Tfp pilus assembly protein PilN COG3167 Tfp pilus assembly protein PilO COG3168 Tfp pilus assembly protein PilP COG3169 uncharacterized protein (DUF486 family) COG3170 Tfp pilus assembly protein FimV COG3171 uncharacterized protein YggL (DUF469 family) COG3172 nicotinamide riboside kinase COG3173 aminoglycoside phosphotransferase (APT) family kinase protein COG3174 uncharacterized membrane protein (DUF4010 family) COG3175 cytochrome c oxidase assembly protein Cox11 COG3176 putative hemolysin COG3177 Fic family protein COG3178 aminoglycoside/choline kinase family phosphotransferase COG3179 predicted chitinase COG3180 uncharacterized membrane protein AbrB (regulator of aidB expression) COG3181 tripartite-type tricarboxylate transporter receptor subunit TctC COG3182 uncharacterized iron-regulated membrane protein COG3183 predicted HNH restriction endonuclease COG3184 hypothetical protein COG3185 4-hydroxyphenylpyruvate dioxygenase-like putative hemolysin COG3186 phenylalanine-4-hydroxylase COG3187 heat shock protein HslJ COG3188 outer membrane usher protein FimD/PapC COG3189 uncharacterized protein YeaO (DUF488 family) COG3190 flagellar biogenesis protein FliO COG3191 L-aminopeptidase/D-esterase-like protein COG3192 ethanolamine transporter EutH COG3193 uncharacterized protein GlcG (DUF336 family) COG3194 ureidoglycolate hydrolase COG3195 2-oxo-4-hydroxy-4-carboxy--5-ureidoimidazoline (OHCU) decarboxylase COG3196 uncharacterized protein CbrC (UPF0167 family) COG3197 nitrogen fixation-related uncharacterized protein COG3198 hypothetical protein COG3199 predicted polyphosphate/ATP-dependent NAD kinase COG3200 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase class II COG3201 nicotinamide riboside transporter PnuC COG3202 ATP/ADP translocase COG3203 predicted porin COG3204 uncharacterized protein YjiK COG3205 uncharacterized membrane protein COG3206 uncharacterized protein involved in exopolysaccharide biosynthesis COG3207 pyoverdine/dityrosine biosynthesis protein Dit1 COG3208 surfactin synthase thioesterase subunit COG3209 uncharacterized protein RhaS with RHS repeats COG3210 large exoprotein involved in heme utilization and adhesion COG3211 secreted PhoX family phosphatase COG3212 uncharacterized membrane protein YkoI COG3213 uncharacterized protein involved in response to NO COG3214 uncharacterized protein YcaQ COG3215 Tfp pilus assembly protein PilZ COG3216 uncharacterized protein (DUF2062 family) COG3217 uncharacterized protein YcbX COG3218 ABC-type uncharacterized transport system auxiliary subunit COG3219 hypothetical protein COG3220 uncharacterized protein (UPF0276 family) COG3221 ABC-type phosphate/phosphonate transport system substrate-binding protein COG3222 glycosyltransferase A (GT-A) superfamily protein (DUF2064 family) COG3223 phosphate starvation-inducible membrane PsiE COG3224 antibiotic biosynthesis monooxygenase (ABM) superfamily enzyme COG3225 ABC-type uncharacterized transport system involved in gliding motility auxiliary subunit COG3226 DNA-binding transcriptional regulator YbjK COG3227 Zn-dependent metalloprotease COG3228 Mlc titration factor MtfA (ptsG expression regulator) COG3230 heme oxygenase COG3231 aminoglycoside phosphotransferase COG3232 5-carboxymethyl-2-hydroxymuconate isomerase COG3233 predicted deacetylase COG3234 uncharacterized protein YfaT (DUF1175 family) COG3235 uncharacterized membrane protein COG3236 predicted NAD-dependent protein-ADP-ribosyltransferase YbiA (DUF1768 family) COG3237 uncharacterized protein YjbJ (UPF0337 family) COG3238 uncharacterized membrane protein YdcZ (DUF606 family) COG3239 fatty acid desaturase COG3240 phospholipase/lecithinase/hemolysin COG3241 azurin COG3242 uncharacterized protein YjeT (DUF2065 family) COG3243 poly(3-hydroxyalkanoate) synthetase COG3245 cytochrome c5 COG3246 uncharacterized protein (DUF849 family) COG3247 uncharacterized membrane protein HdeD (DUF308 family) COG3248 nucleoside-specific outer membrane channel protein Tsx COG3249 hypothetical protein COG3250 beta-galactosidase/beta-glucuronidase COG3251 uncharacterized protein YbdZ (MbtH family) COG3252 methenyltetrahydromethanopterin cyclohydrolase COG3253 chlorite dismutase COG3254 L-rhamnose mutarotase COG3255 putative sterol carrier protein COG3256 nitric oxide reductase large subunit COG3257 glyoxylate utilization-related uncharacterized protein COG3258 cytochrome c COG3259 coenzyme F420-reducing hydrogenase alpha subunit COG3260 Ni,Fe-hydrogenase III small subunit COG3261 Ni,Fe-hydrogenase III large subunit COG3262 Ni,Fe-hydrogenase III component G COG3263 NhaP-type Na+/H+ and K+/H+ antiporter COG3264 small-conductance mechanosensitive channel COG3265 gluconate kinase COG3266 septal ring-binding cell division protein DamX COG3267 type II secretory pathway predicted ATPase ExeA COG3268 short subunit dehydrogenase-like uncharacterized protein COG3269 predicted RNA-binding protein with TRAM domain COG3270 NOL1/NOP2/fmu family ribosome biogenesis protein COG3271 predicted double-glycine peptidase COG3272 uncharacterized protein YbgA (DUF1722 family) COG3273 uncharacterized protein with PhoU and TrkA domain COG3274 surface polysaccharide O-acyltransferase-like enzyme COG3275 LytS/YehU family sensor histidine kinase COG3276 selenocysteine-specific translation elongation factor COG3277 rRNA processing protein Gar1 COG3278 cbb3-type cytochrome oxidase subunit 1 COG3279 DNA-binding LytR/AlgR family response regulator COG3280 maltooligosyltrehalose synthase COG3281 predicted trehalose synthase COG3283 transcriptional regulator of aromatic amino acid metabolism COG3284 transcriptional regulator of acetoin/glycerol metabolism COG3285 DNA primase COG3286 hypothetical protein COG3287 hypothetical protein COG3288 NAD/NADP transhydrogenase alpha subunit COG3290 sensor histidine kinase regulating citrate/malate metabolism COG3291 PKD repeat protein COG3292 ligand-binding sensor domain-containing protein COG3293 transposase COG3294 metal-dependent HD superfamily phosphatase/phosphodiesterase COG3295 hypothetical protein COG3296 uncharacterized Tic20 family protein COG3297 type II secretory pathway component PulL COG3298 predicted PolB exonuclease-like 3'-5' exonuclease COG3299 uncharacterized phage protein gp47/JayE COG3300 NO-binding membrane sensor protein with MHYT domain COG3301 formate-dependent nitrite reductase membrane component NrfD COG3302 DMSO reductase anchor subunit COG3303 formate-dependent nitrite reductase cytochrome c552 subunit COG3304 uncharacterized membrane protein YccF (DUF307 family) COG3305 uncharacterized membrane protein (DUF2068 family) COG3306 GR25 family glycosyltransferase involved in LPS biosynthesis COG3307 O-antigen ligase COG3308 uncharacterized membrane protein COG3309 virulence-associated protein VapD COG3310 hypothetical protein COG3311 predicted DNA-binding transcriptional regulator AlpA COG3312 F0F1-type ATP synthase assembly protein I COG3313 predicted Fe-S protein YdhL (DUF1289 family) COG3314 nucleoside recognition membrane protein YjiH COG3315 O-methyltransferase involved in polyketide biosynthesis COG3316 transposase-like protein COG3317 uncharacterized lipoprotein COG3318 uncharacterized protein YecA (UPF0149 family) COG3319 thioesterase domain-containing protein COG3320 thioester reductase-like protein COG3321 acyl transferase domain-containing protein COG3322 sensor domain CHASE-containing protein COG3323 hypothetical protein COG3324 predicted enzyme related to lactoylglutathione lyase COG3325 GH18 family chitinase COG3326 uncharacterized membrane protein YsdA (DUF1294 family) COG3327 DNA-binding transcriptional regulator PaaX COG3328 transposase-like protein COG3329 hypothetical protein COG3330 hypothetical protein COG3331 penicillin-binding protein-related factor A (putative recombinase) COG3332 uncharacterized protein with NRDE domain COG3333 TctA family transporter COG3334 flagellar motility protein MotE (MotC chaperone) COG3335 transposase COG3336 cytochrome c oxidase assembly factor CtaG COG3337 CRISPR/Cas system CMR-associated protein Cmr5 small subunit COG3338 carbonic anhydrase COG3339 uncharacterized membrane protein YkvA (DUF1232 family) COG3340 peptidase E COG3341 viroplasmin and RNaseH domain-containing protein COG3342 uncharacterized Ntn-hydrolase superfamily protein COG3343 DNA-directed RNA polymerase delta subunit COG3344 retron-type reverse transcriptase COG3345 alpha-galactosidase COG3346 cytochrome oxidase assembly protein ShyY1 COG3347 rhamnose utilization protein RhaD (predicted bifunctional aldolase and dehydrogenase) COG3349 uncharacterized protein with NAD-binding domain and iron-sulfur cluster COG3350 YHS domain-containing protein COG3351 archaellum component FlaD/FlaE COG3352 archaellum component FlaC COG3353 archaellum component FlaF (FlaF/FlaG flagellin family) COG3354 archaellum component FlaG (FlaF/FlaG flagellin family) COG3355 predicted transcriptional regulator COG3356 predicted neutral ceramidase superfamily lipid hydrolase COG3357 predicted Zn-ribbon and HTH transcriptional regulator COG3358 uncharacterized protein (DUF1684 family) COG3359 uncharacterized protein YprB with RNaseH-like and TPR domain COG3360 flavin-binding protein dodecin COG3361 uncharacterized protein YqjF (DUF2071 family) COG3363 IMP cyclohydrolase COG3364 predicted nucleic acid-binding Zn-ribbon protein COG3365 hypothetical protein COG3366 hypothetical protein COG3367 uncharacterized NAD-dependent epimerase/dehydratase family protein COG3368 predicted permease COG3369 CDGSH-type Zn-finger protein COG3370 hypothetical protein COG3371 hypothetical membrane protein COG3372 predicted nuclease of restriction endonuclease-like RecB superfamily COG3373 predicted transcriptional regulator with HTH domain COG3374 uncharacterized membrane protein COG3375 predicted GNAT superfamily acetyltransferase COG3376 high-affinity nickel permease COG3377 uncharacterized protein YunC (DUF1805 family) COG3378 phage/plasmid-associated DNA primase COG3379 predicted AlkP superfamily phosphohydrolase/phosphomutase COG3380 predicted NAD/FAD-dependent oxidoreductase COG3381 TorA maturation chaperone TorD COG3382 DNA/RNA-binding domain of Phe-tRNA-synthetase-like protein COG3383 predicted molibdopterin-dependent oxidoreductase YjgC COG3384 aromatic ring-opening dioxygenase catalytic subunit (LigB family) COG3385 IS4 transposase COG3386 sugar lactone lactonase YvrE COG3387 GH15 family glucan-1,4-alpha-glucosidase COG3388 predicted transcriptional regulator COG3389 presenilin-like A22 family membrane protease COG3390 RPA family protein COG3391 DNA-binding beta-propeller fold protein YncE COG3392 adenine-specific DNA methylase COG3393 predicted GNAT family acetyltransferase COG3394 predicted glycoside hydrolase/deacetylase ChbG (UPF0249 family) COG3395 uncharacterized protein YgbK (DUF1537 family) COG3396 1,2-phenylacetyl-CoA epoxidase catalytic subunit COG3397 predicted carbohydrate-binding protein with CBM5 and CBM33 domain COG3398 predicted transcriptional regulator COG3399 hypothetical protein COG3400 hypothetical protein COG3401 fibronectin type 3 domain-containing protein COG3402 membrane protein YdbS with pleckstrin-like domain COG3403 FPC/CPF motif-containing protein YcgG COG3404 formiminotetrahydrofolate cyclodeaminase COG3405 endo-1,4-beta-D-glucanase Y COG3407 mevalonate pyrophosphate decarboxylase COG3408 glycogen debranching enzyme COG3409 peptidoglycan hydrolase-like protein with peptidoglycan-binding domain COG3410 DUF2075 family protein COG3411 (2Fe-2S) ferredoxin COG3412 dihydroxyacetone kinase DhaKLM complex PTS-EIIA-like component DhaM COG3413 predicted DNA binding protein COG3414 galactitol-specific phosphotransferase system IIB component COG3415 transposase COG3416 hypothetical protein COG3417 PBP1b-binding outer membrane lipoprotein LpoB COG3418 flagellar biosynthesis/type III secretory pathway chaperone COG3419 Tfp pilus tip-associated adhesin PilY1 COG3420 nitrous oxidase accessory protein NosD COG3421 hypothetical protein COG3422 uncharacterized protein YegP (UPF0339 family) COG3423 lambda repressor-like predicted transcriptional regulator COG3424 predicted naringenin-chalcone synthase COG3425 3-hydroxy-3-methylglutaryl CoA synthase COG3426 butyrate kinase COG3427 carbon monoxide dehydrogenase subunit G COG3428 uncharacterized membrane protein YdbT with pleckstrin-like domain COG3429 glucose-6-phosphate dehydrogenase assembly protein OpcA COG3430 FlaG/FlaF family flagellin (archaellin) COG3431 uncharacterized membrane protein (DUF373 family) COG3432 predicted transcriptional regulator COG3433 aryl carrier-like protein COG3434 c-di-GMP-related signal transduction protein COG3435 gentisate 1,2-dioxygenase COG3436 transposase COG3437 response regulator RpfG family c-di-GMP phosphodiesterase COG3439 uncharacterized protein (DUF302 family) COG3440 predicted restriction endonuclease COG3442 CobQ-like glutamine amidotransferase family enzyme COG3443 Zn/Cd-binding protein ZinT COG3444 mannose/fructose/N-acetylgalactosamine-specific phosphotransferase system component IIB COG3445 autonomous glycyl radical cofactor GrcA COG3447 integral membrane sensor domain MASE1 COG3448 CBS-domain-containing membrane protein COG3449 DNA gyrase inhibitor GyrI COG3450 uncharacterized cupin superfamily protein COG3451 type IV secretory pathway VirB4 component COG3452 sensor domain CHASE-containing protein COG3453 protein tyrosine phosphatase (PTP) superfamily phosphohydrolase (DUF442 family) COG3454 alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase PhnM COG3455 type VI protein secretion system component VasF COG3456 predicted component of type VI protein secretion system COG3457 predicted amino acid racemase COG3458 cephalosporin-C deacetylase-like acetyl esterase COG3459 cellobiose phosphorylase COG3460 1,2-phenylacetyl-CoA epoxidase PaaB subunit COG3461 hypothetical protein COG3462 uncharacterized membrane protein COG3463 uncharacterized membrane protein COG3464 transposase COG3465 uncharacterized protein YwgA COG3466 putative transposon-encoded protein COG3467 nitroimidazol reductase NimA-like FMN-containing flavoprotein (pyridoxamine 5'-phosphate oxidase superfamily) COG3468 type V secretory pathway adhesin AidA COG3469 chitinase COG3470 uncharacterized protein involved in high-affinity Fe2+ transport COG3471 predicted secreted protein COG3472 hypothetical protein COG3473 maleate cis-trans isomerase COG3474 cytochrome c2 COG3475 phosphorylcholine metabolism protein LicD COG3476 tryptophan-rich sensory protein COG3477 uncharacterized membrane protein YagU involved in acid resistance COG3478 predicted nucleic-acid-binding Zn-ribbon protein COG3479 phenolic acid decarboxylase COG3480 PDZ domain-containing secreted protein COG3481 23S rRNA maturation-related 3'-5' exoribonuclease YhaM COG3482 hypothetical protein COG3483 tryptophan 2,3-dioxygenase COG3484 predicted proteasome-type protease COG3485 protocatechuate 3,4-dioxygenase beta subunit COG3486 lysine/ornithine N-monooxygenase COG3487 uncharacterized iron-regulated protein COG3488 CxxC motif-containing protein (DUF1111 family) COG3489 predicted lipoprotein COG3490 hypothetical protein COG3491 isopenicillin N synthase-like dioxygenase COG3492 hypothetical protein COG3493 Na+/citrate or Na+/malate symporter COG3494 DUF1009 family protein COG3495 hypothetical protein COG3496 DUF1365 family protein COG3497 phage tail sheath protein FI COG3498 phage tail tube protein FII COG3499 phage protein U COG3500 phage protein D COG3501 uncharacterized protein involved in type VI secretion and phage assembly COG3502 uncharacterized protein (DUF952 family) COG3503 uncharacterized membrane protein COG3504 type IV secretory pathway VirB9-like protein COG3505 type IV secretory pathway TraG/TraD family ATPase VirD4 COG3506 regulation of enolase protein 1 (concanavalin A-like superfamily) COG3507 beta-xylosidase COG3508 homogentisate 1,2-dioxygenase COG3509 poly(3-hydroxybutyrate) depolymerase COG3510 cephalosporin hydroxylase COG3511 phospholipase C COG3512 CRISPR/Cas system-associated protein endoribonuclease Cas2 COG3513 CRISPR/Cas system Type II protein with McrA/HNH and RuvC-like nuclease domain COG3514 uncharacterized protein (DUF4415 family) COG3515 predicted component of type VI protein secretion system COG3516 predicted component of type VI protein secretion system COG3517 predicted component of type VI protein secretion system COG3518 predicted component of type VI protein secretion system COG3519 type VI protein secretion system component VasA COG3520 predicted component of type VI protein secretion system COG3521 predicted component of type VI protein secretion system COG3522 predicted component of type VI protein secretion system COG3523 type VI protein secretion system component VasK COG3524 capsule polysaccharide export protein KpsE/RkpR COG3525 N-acetyl-beta-hexosaminidase COG3526 predicted Rdx family selenoprotein COG3527 alpha-acetolactate decarboxylase COG3528 hypothetical protein COG3529 Zn ribbon nucleic-acid-binding protein COG3530 uncharacterized protein (DUF3820 family) COG3531 protein-disulfide isomerase-like protein with CxxC motif COG3533 DUF1680 family protein COG3534 alpha-L-arabinofuranosidase COG3535 DUF917 family protein COG3536 DUF971 family protein COG3537 putative alpha-1,2-mannosidase COG3538 meiotically up-regulated gene 157 (Mug157) protein COG3539 type 1 fimbria pilin COG3540 phosphodiesterase/alkaline phosphatase D-like protein COG3541 predicted nucleotidyltransferase COG3542 predicted cupin superfamily sugar epimerase COG3543 hypothetical protein COG3544 uncharacterized protein (DUF305 family) COG3545 predicted alpha/beta hydrolase family esterase COG3546 Mn-containing catalase COG3547 transposase COG3548 uncharacterized membrane protein COG3549 plasmid maintenance system killer protein COG3550 serine/threonine protein kinase HipA of HipAB toxin-antitoxin module COG3551 hypothetical protein COG3552 uncharacterized protein with von Willebrand factor type A (vWA) domain COG3553 hypothetical protein COG3554 hypothetical protein COG3555 aspartyl/asparaginyl beta-hydroxylase (cupin superfamily) COG3556 uncharacterized membrane protein COG3557 protein associated with RNAse G/E COG3558 nuclear transport factor 2 (NTF2) superfamily protein COG3559 putative exporter of polyketide antibiotics COG3560 predicted oxidoreductase (fatty acid repression mutant protein) COG3561 phage anti-repressor protein COG3562 capsule polysaccharide modification protein KpsS COG3563 capsule polysaccharide export protein KpsC/LpsZ COG3564 uncharacterized protein (DUF779 family) COG3565 extradiol dioxygenase family protein COG3566 hypothetical protein COG3567 hypothetical protein COG3568 endonuclease/exonuclease/phosphatase family metal-dependent hydrolase COG3569 DNA topoisomerase IB COG3570 streptomycin 6-kinase COG3571 predicted alpha/beta-hydrolase family hydrolase COG3572 gamma-glutamylcysteine synthetase COG3573 predicted oxidoreductase COG3575 hypothetical protein COG3576 predicted pyridoxine 5'-phosphate oxidase superfamily flavin-nucleotide-binding protein COG3577 predicted aspartyl protease COG3579 aminopeptidase C COG3580 predicted nucleotide-binding protein (sugar kinase/HSP70/actin superfamily) COG3581 predicted nucleotide-binding protein (sugar kinase/HSP70/actin superfamily) COG3582 predicted nucleic acid binding AN1-type Zn finger protein COG3583 uncharacterized protein YabE (DUF348 family) COG3584 3D (Asp-Asp-Asp) domain-containing protein COG3585 molybdopterin-binding protein COG3586 predicted transport protein COG3587 restriction endonuclease COG3588 fructose-bisphosphate aldolase class 1 COG3589 hypothetical protein COG3590 predicted metalloendopeptidase COG3591 V8-like Glu-specific endopeptidase COG3592 uncharacterized Fe-S cluster protein YjdI COG3593 predicted ATP-dependent endonuclease of OLD family COG3594 fucose 4-O-acetylase-like acetyltransferase COG3595 DUF4097 and DUF4098 domain-containing protein YvlB COG3596 predicted GTPase COG3597 uncharacterized protein (DUF697 family) COG3598 RecA-family ATPase COG3599 cell division septum initiation protein DivIVA COG3600 uncharacterized phage-associated protein COG3601 riboflavin transporter FmnP COG3602 hypothetical protein COG3603 hypothetical protein COG3604 transcriptional regulator with GAF, ATPase, and Fis domain COG3605 signal transduction protein with GAF and PtsI domain COG3607 predicted lactoylglutathione lyase COG3608 predicted deacylase COG3609 Arc/MetJ-type ribon-helix-helix transcriptional regulator COG3610 uncharacterized membrane protein YjjB (DUF3815 family) COG3611 replication initiation and membrane attachment protein DnaB COG3612 hypothetical protein COG3613 nucleoside 2-deoxyribosyltransferase COG3614 CHASE1-domain containing sensor protein COG3615 tellurite resistance-related uncharacterized protein COG3616 D-serine deaminase-like pyridoxal phosphate-dependent protein COG3617 prophage antirepressor-like protein COG3618 predicted TIM-barrel fold metal-dependent hydrolase COG3619 uncharacterized membrane protein YoaK (UPF0700 family) COG3620 predicted transcriptional regulator COG3621 patatin-like phospholipase/acyl hydrolase COG3622 hydroxypyruvate isomerase COG3623 L-ribulose-5-phosphate 3-epimerase UlaE COG3624 alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnG COG3625 alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnH COG3626 alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnI COG3627 alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase COG3628 phage baseplate assembly protein W COG3629 DNA-binding SARP family transcriptional activator COG3630 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase gamma subunit COG3631 ketosteroid isomerase-like protein COG3633 Na+/serine symporter COG3634 alkyl hydroperoxide reductase subunit AhpF COG3635 2,3-bisphosphoglycerate-independent phosphoglycerate mutase COG3636 DNA-binding phage protein COG3637 opacity protein-like surface antigen COG3638 ABC-type phosphate/phosphonate transport system ATPase subunit COG3639 ABC-type phosphate/phosphonate transport system permease subunit COG3640 CO dehydrogenase nickel-insertion accessory protein CooC1 COG3641 uncharacterized membrane protein COG3642 tRNA A-37 threonylcarbamoyl transferase component Bud32 COG3643 glutamate formiminotransferase COG3644 hypothetical protein COG3645 phage antirepressor YoqD-like protein COG3646 phage regulator Rha-like protein COG3647 uncharacterized membrane protein YjdF COG3648 urate oxidase COG3649 CRISPR/Cas system type I-B associated protein Csh2 (Cas7 group RAMP superfamily) COG3650 uncharacterized membrane protein COG3651 uncharacterized protein (DUF2237 family) COG3652 predicted outer membrane protein COG3653 N-acyl-D-aspartate/D-glutamate deacylase COG3654 prophage maintenance system killer protein COG3655 DNA-binding Xre family transcriptional regulator COG3656 hypothetical protein COG3657 putative component of toxin-antitoxin plasmid stabilization module COG3658 cytochrome b COG3659 carbohydrate-selective porin OprB COG3660 mitochondrial fission protein ELM1 COG3661 alpha-glucuronidase COG3662 uncharacterized protein (DUF2236 family) COG3663 G:T/U-mismatch repair DNA glycosylase COG3664 beta-xylosidase COG3665 uncharacterized protein YcgI (DUF1989 family) COG3666 transposase COG3667 uncharacterized protein involved in copper resistance COG3668 plasmid stabilization system protein ParE COG3669 alpha-L-fucosidase COG3670 carotenoid cleavage dioxygenase-like enzyme COG3671 uncharacterized membrane protein COG3672 predicted transglutaminase-like cysteine proteinase COG3673 uncharacterized protein (DUF2235 family) COG3675 predicted lipase COG3676 transposase-like protein COG3677 transposase-like protein COG3678 Spy/CpxP family protein refolding chaperone COG3679 cell fate (sporulation/competence/biofilm development) regulator YlbF (YheA/YmcA/DUF963 family) COG3680 hypothetical protein COG3681 L-cysteine desulfidase COG3682 predicted transcriptional regulator COG3683 ABC-type uncharacterized transport system substrate-binding protein COG3684 tagatose-1,6-bisphosphate aldolase COG3685 ferritin-like metal-binding protein YciE COG3686 uncharacterized MAPEG superfamily protein COG3687 predicted metal-dependent hydrolase COG3688 predicted RNA-binding protein with PIN domain COG3689 uncharacterized membrane protein YcgQ (UPF0703/DUF1980 family) COG3691 uncharacterized protein YfcZ (UPF0381/DUF406 family) COG3692 uncharacterized protein YifN (PemK superfamily) COG3693 GH35 family endo-1,4-beta-xylanase COG3694 ABC-type uncharacterized transport system permease subunit COG3695 alkylated DNA nucleotide flippase Atl1 COG3696 Cu/Ag efflux pump CusA COG3697 phosphoribosyl-dephospho-CoA transferase COG3698 uncharacterized protein YigE (DUF2233 family) COG3700 acid phosphatase class B COG3701 type IV secretory pathway TrbF-like protein COG3702 type IV secretory pathway VirB3-like protein COG3703 cation transport regulator ChaC COG3704 type IV secretory pathway VirB6-like protein COG3705 ATP phosphoribosyltransferase regulatory subunit HisZ COG3706 PleD family two-component response regulator COG3707 AmiR/NasT family two-component response regulator COG3708 predicted transcriptional regulator YdeE COG3709 ribose 1,5-bisphosphokinase PhnN COG3710 DNA-binding winged helix-turn-helix (wHTH) protein COG3711 transcriptional antiterminator COG3712 ferric-dicitrate binding protein FerR (iron transport regulator) COG3713 outer membrane scaffolding protein for murein synthesis (MipA/OmpV family) COG3714 uncharacterized membrane protein YhhN COG3715 mannose/fructose/N-acetylgalactosamine-specific phosphotransferase system component IIC COG3716 mannose/fructose/N-acetylgalactosamine-specific phosphotransferase system component IID COG3717 5-keto 4-deoxyuronate isomerase COG3718 5-deoxy-D-glucuronate isomerase COG3719 ribonuclease I COG3720 putative heme degradation protein COG3721 putative heme iron utilization protein COG3722 DNA-binding MltR family transcriptional regulator COG3723 recombinational DNA repair protein RecT COG3724 succinylarginine dihydrolase COG3725 membrane protein required for beta-lactamase induction COG3726 uncharacterized membrane protein affecting hemolysin expression COG3727 G:T-mismatch repair DNA endonuclease (very short patch repair protein) COG3728 phage terminase small subunit COG3729 general stress protein YciG COG3730 sorbitol-specific phosphotransferase system component IIC COG3731 sorbitol-specific phosphotransferase system component IIA COG3732 sorbitol-specific phosphotransferase system component IIBC COG3733 Cu2+-containing amine oxidase COG3734 2-keto-3-deoxy-galactonokinase COG3735 uncharacterized protein YbaP (TraB family) COG3736 type IV secretory pathway component VirB8 COG3737 uncharacterized protein COG3738 uncharacterized protein YijF (DUF1287 family) COG3739 uncharacterized membrane protein YoaT (DUF817 family) COG3740 phage head maturation protease COG3741 N-formylglutamate amidohydrolase COG3742 uncharacterized protein with PIN domain COG3743 predicted flap endonuclease-1-like 5' DNA nuclease COG3744 PIN domain nuclease of toxin-antitoxin system COG3745 Flp pilus assembly protein CpaB COG3746 phosphate-selective porin COG3747 phage terminase small subunit COG3748 uncharacterized membrane protein COG3749 uncharacterized protein (DUF934 family) COG3750 uncharacterized protein (UPF0335 family) COG3751 Rps23 Pro-64 3,4-dihydroxylase Tpa1-like proline 4-hydroxylase COG3752 steroid 5-alpha reductase family enzyme COG3753 uncharacterized protein YidB (DUF937 family) COG3754 lipopolysaccharide biosynthesis protein COG3755 uncharacterized protein YecT (DUF1311 family) COG3756 uncharacterized protein YdaU (DUF1376 family) COG3757 GH25 family lysozyme M1 (1,4-beta-N-acetylmuramidase) COG3758 environmental stress-induced protein Ves COG3759 uncharacterized membrane protein COG3760 hypothetical protein COG3761 NADH:ubiquinone oxidoreductase subunit COG3762 uncharacterized membrane protein COG3763 uncharacterized protein YneF (UPF0154 family) COG3764 sortase (surface protein transpeptidase) COG3765 LPS O-antigen subunit length determinant protein (WzzB/FepE family) COG3766 uncharacterized membrane protein YjfL (UPF0719 family) COG3767 uncharacterized low-complexity protein COG3768 uncharacterized membrane protein YcjF (UPF0283 family) COG3769 predicted mannosyl-3-phosphoglycerate phosphatase (HAD superfamily) COG3770 murein endopeptidase COG3771 uncharacterized membrane protein YciS (DUF1049 family) COG3772 GH24 family phage-related lysozyme (muramidase) COG3773 spore germination cell wall hydrolase CwlJ-like protein COG3774 mannosyltransferase OCH1-like enzyme COG3775 galactitol-specific phosphotransferase system IIC component COG3776 uncharacterized protein YhhL (DUF1145 family) COG3777 hydroxyacyl-ACP dehydratase HTD2-like protein with hotdog domain COG3778 uncharacterized protein YmfQ (DUF2313 family) COG3779 uncharacterized protein YegJ (DUF2314 family) COG3780 intein-encoded DNA endonuclease-like protein COG3781 predicted membrane chloride channel (bestrophin family) COG3782 hypothetical protein COG3783 soluble cytochrome b562 COG3784 uncharacterized protein YdbL (DUF1318 family) COG3785 heat shock protein HspQ COG3786 L,D-peptidoglycan transpeptidase YkuD (ErfK/YbiS/YcfS/YnhG family) COG3787 uncharacterized protein YhbP (UPF0306 family) COG3788 uncharacterized membrane protein YecN with MAPEG domain COG3789 uncharacterized protein YjfI (DUF2170 family) COG3790 predicted membrane protein COG3791 hypothetical protein COG3792 hypothetical protein COG3793 tellurite resistance protein COG3794 plastocyanin COG3795 hypothetical protein COG3797 uncharacterized protein (DUF1697 family) COG3798 hypothetical protein COG3799 methylaspartate ammonia-lyase COG3800 predicted transcriptional regulator COG3801 hypothetical protein COG3802 hypothetical protein COG3803 uncharacterized protein (DUF924 family) COG3804 hypothetical protein COG3805 aromatic ring-cleaving dioxygenase COG3806 anti-sigma factor ChrR (cupin superfamily) COG3807 SH3-like domain-containing protein COG3808 Na+/H+-translocating membrane pyrophosphatase COG3809 Zn-finger nucleic acid-binding protein COG3811 uncharacterized protein YjhX (UPF0386 family) COG3812 hypothetical protein COG3813 hypothetical protein COG3814 hypothetical protein COG3815 uncharacterized membrane protein COG3816 hypothetical protein COG3817 uncharacterized membrane protein COG3818 predicted GNAT superfamily acetyltransferase COG3819 uncharacterized membrane protein COG3820 hypothetical protein COG3821 uncharacterized membrane protein COG3822 D-lyxose ketol-isomerase COG3823 glutamine cyclotransferase COG3824 predicted Zn-dependent protease with MMP-like domain COG3825 uncharacterized protein with von Willebrand factor type A (vWA) domain COG3826 hypothetical protein COG3827 cell pole-organizing protein PopZ COG3828 type 1 glutamine amidotransferase COG3829 transcriptional regulator with PAS, ATPase and Fis domain COG3830 predicted amino acid-binding ACT domain protein COG3831 predicted DNA-binding WGR domain protein COG3832 uncharacterized protein YndB with AHSA1/START domain COG3833 ABC-type maltose transport system permease subunit COG3835 sugar diacid utilization regulator COG3836 2-keto-3-deoxy-L-rhamnonate aldolase RhmA COG3837 uncharacterized cupin superfamily protein COG3838 type IV secretory pathway VirB2 component (pilin) COG3839 ABC-type sugar transport system ATPase subunit COG3840 ABC-type thiamine transport system ATPase subunit COG3842 ABC-type Fe3+/spermidine/putrescine transport system ATPase subunit COG3843 type IV secretory pathway VirD2 relaxase COG3844 kynureninase COG3845 ABC-type uncharacterized transport system ATPase subunit COG3846 type IV secretory pathway TrbL component COG3847 Flp pilus assembly pilin Flp COG3848 phosphohistidine swiveling domain-containing protein COG3850 nitrate/nitrite-specific signal transduction histidine kinase COG3851 glucose-6-phosphate-specific signal transduction histidine kinase COG3852 nitrogen-specific signal transduction histidine kinase COG3853 uncharacterized protein YaaN involved in tellurite resistance COG3854 stage III sporulation protein SpoIIIAA COG3855 fructose-1,6-bisphosphatase COG3856 small basic protein COG3857 ATP-dependent helicase/DNAse subunit B COG3858 spore germination protein YaaH COG3859 thiamine transporter ThiT COG3860 hypothetical protein COG3861 stress response protein YsnF COG3862 CxxC motif-containing protein COG3863 uncharacterized protein YycO COG3864 predicted metal-dependent peptidase COG3865 predicted 3-demethylubiquinone-9 3-methyltransferase (glyoxalase superfamily) COG3866 pectate lyase COG3867 arabinogalactan endo-1,4-beta-galactosidase COG3868 hypothetical protein COG3869 protein-arginine kinase COG3870 uncharacterized protein YaaQ COG3871 general stress protein 26 COG3872 uncharacterized protein YqhQ COG3874 uncharacterized spore protein YtfJ COG3875 nickel-dependent lactate racemase COG3876 uncharacterized protein YbbC (DUF1343 family) COG3877 hypothetical protein COG3878 uncharacterized protein YwqG COG3879 uncharacterized protein YlxW (UPF0749 family) COG3880 protein-arginine kinase activator protein McsA COG3881 uncharacterized protein YrrD COG3882 predicted enzyme involved in methoxymalonyl-ACP biosynthesis COG3883 peptidoglycan hydrolase CwlO-like protein COG3884 acyl-ACP thioesterase COG3885 aromatic ring-opening dioxygenase LigB subunit COG3886 HKD family nuclease COG3887 c-di-AMP phosphodiesterase-like protein COG3888 predicted transcriptional regulator COG3889 hypothetical protein COG3890 phosphomevalonate kinase COG3892 myo-inositol catabolism protein IolC COG3893 inactivated superfamily I helicase COG3894 uncharacterized 2Fe-2S/4Fe-4S cluster protein (DUF4445 family) COG3895 membrane-bound inhibitor of C-type lysozyme COG3896 chloramphenicol 3-O-phosphotransferase COG3897 predicted nicotinamide N-methyase COG3898 uncharacterized membrane-anchored protein COG3899 predicted ATPase COG3900 hypothetical protein COG3901 transcriptional regulator of nitric oxide reductase COG3903 predicted ATPase COG3904 hypothetical protein COG3905 predicted transcriptional regulator COG3906 uncharacterized protein YrzB (UPF0473 family) COG3907 membrane-associated PAP2 superfamily phosphatase COG3908 hypothetical protein COG3909 cytochrome c556 COG3910 predicted ATPase COG3911 predicted ATPase COG3913 hypothetical protein COG3914 predicted O-linked N-acetylglucosamine transferase (SPINDLY family) COG3915 hypothetical protein COG3916 N-acyl-L-homoserine lactone synthetase COG3917 2-hydroxychromene-2-carboxylate isomerase COG3918 uncharacterized membrane protein COG3919 predicted ATP-grasp superfamily ATP-dependent carboligase COG3920 two-component sensor histidine kinase COG3921 hypothetical protein COG3923 primosomal protein N'' COG3924 uncharacterized membrane protein YhdT COG3925 fructose-specific component phosphotransferase system IIB-like protein COG3926 lysozyme family protein COG3930 hypothetical protein COG3931 predicted N-formylglutamate amidohydrolase COG3932 hypothetical protein COG3933 transcriptional regulatory protein LevR COG3934 endo-1,4-beta-mannosidase COG3935 DNA replication protein DnaD COG3936 membrane-bound acyltransferase YfiQ involved in biofilm formation COG3937 polyhydroxyalkanoate synthesis regulator phasin COG3938 proline racemase COG3940 GH43 family beta-xylosidase COG3941 phage tail tape-measure protein COG3942 surface antigen COG3943 hypothetical protein COG3944 capsular polysaccharide biosynthesis protein COG3945 hemerythrin-like domain-containing protein COG3946 type IV secretory pathway VirJ component COG3947 two-component SAPR family response regulator COG3948 phage-related baseplate assembly protein COG3949 uncharacterized membrane protein YkvI COG3950 predicted ATP-binding protein involved in virulence COG3951 Rod binding domain-containing protein COG3952 lipid-A-disaccharide synthase-like uncharacterized protein COG3953 SLT domain-containing protein COG3954 phosphoribulokinase COG3955 uncharacterized protein (DUF1919 family) COG3956 uncharacterized protein YabN with tetrapyrrole methylase and pyrophosphatase domain COG3957 phosphoketolase COG3958 transketolase C-terminal domain/subunit COG3959 transketolase N-terminal domain/subunit COG3960 glyoxylate carboligase COG3961 TPP-dependent 2-oxoacid decarboxylase COG3962 TPP-dependent trihydroxycyclohexane-1,2-dione (THcHDO) dehydratase COG3963 phospholipid N-methyltransferase COG3964 predicted amidohydrolase COG3965 predicted Co/Zn/Cd cation transporter (cation efflux family) COG3966 poly-D-alanine transfer protein DltD COG3967 short-subunit dehydrogenase involved in D-alanine esterification of teichoic acids COG3968 glutamine synthetase type III COG3969 predicted phosphoadenosine phosphosulfate sulfurtransferase COG3970 fumarylacetoacetate (FAA) hydrolase family protein COG3971 2-keto-4-pentenoate hydratase COG3972 superfamily I DNA and RNA helicase COG3973 DNA helicase IV COG3975 predicted metalloprotease with PDZ domain COG3976 uncharacterized protein with FMN-binding domain COG3977 alanine-alpha-ketoisovalerate/valine-pyruvate aminotransferase COG3978 acetolactate synthase regulatory subunit COG3979 chitodextrinase COG3980 spore coat polysaccharide biosynthesis predicted glycosyltransferase SpsG COG3981 predicted acetyltransferase COG4001 hypothetical protein COG4002 predicted methyltransferase MtxX (methanogen marker protein 4) COG4003 hypothetical protein COG4004 hypothetical protein COG4006 CRISPR/Cas system-associated protein Csm6 COG4007 H2-forming N5,N10-methylenetetrahydromethanopterin dehydrogenase-like enzyme COG4008 predicted metal-binding transcription factor (methanogenesis marker protein 9) COG4009 hypothetical protein COG4010 hypothetical protein COG4012 uncharacterized protein (DUF1786 family) COG4013 hypothetical protein COG4014 hypothetical protein COG4015 predicted ThiF/HesA family dinucleotide-utilizing enzyme COG4016 uncharacterized protein (UPF0254 family) COG4017 hypothetical protein COG4018 hypothetical protein COG4019 hypothetical protein COG4020 hypothetical protein COG4021 tRNA(His) 5'-end guanylyltransferase COG4022 hypothetical protein COG4023 preprotein translocase subunit Sec61beta COG4024 hypothetical protein COG4025 uncharacterized membrane protein COG4026 predicted nuclease with TOPRIM domain COG4027 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase COG4028 predicted P-loop ATPase/GTPase COG4029 hypothetical protein COG4030 predicted HAD superfamily phosphohydrolase COG4031 hypothetical protein COG4032 sulfopyruvate decarboxylase TPP-binding subunit COG4033 hypothetical protein COG4034 hypothetical protein COG4035 uncharacterized membrane protein COG4036 energy-converting hydrogenase Eha subunit G COG4037 energy-converting hydrogenase Eha subunit F COG4038 energy-converting hydrogenase Eha subunit E COG4039 energy-converting hydrogenase Eha subunit C COG4040 uncharacterized membrane protein COG4041 energy-converting hydrogenase Eha subunit B COG4042 energy-converting hydrogenase Eha subunit A COG4043 ASC-1-like (ASCH) protein COG4044 hypothetical protein COG4046 hypothetical protein COG4047 N-glycosylase/DNA lyase COG4048 hypothetical protein COG4049 uncharacterized C2H2 Zn-finger protein COG4050 hypothetical protein COG4051 hypothetical protein COG4052 methyl coenzyme M reductase subunit C-like uncharacterized protein (methanogenesis marker protein 7) COG4053 hypothetical protein COG4054 methyl coenzyme M reductase beta subunit COG4055 methyl coenzyme M reductase subunit D COG4056 methyl coenzyme M reductase subunit C COG4057 methyl coenzyme M reductase gamma subunit COG4058 methyl coenzyme M reductase alpha subunit COG4059 tetrahydromethanopterin S-methyltransferase subunit E COG4060 tetrahydromethanopterin S-methyltransferase subunit D COG4061 tetrahydromethanopterin S-methyltransferase subunit C COG4062 tetrahydromethanopterin S-methyltransferase subunit B COG4063 tetrahydromethanopterin S-methyltransferase subunit A COG4064 tetrahydromethanopterin S-methyltransferase subunit G COG4065 hypothetical protein COG4066 uncharacterized protein (UPF0305 family) COG4067 hypothetical protein COG4068 predicted nucleic acid-binding Zn ribbon protein COG4069 hypothetical protein COG4070 UPF0288 family protein (methanogenesis marker protein 3) COG4071 F420-0:gamma-glutamyl ligase-like protein COG4072 hypothetical protein COG4073 hypothetical protein COG4074 5,10-methenyltetrahydromethanopterin hydrogenase COG4075 nitrogen regulatory protein PII-like uncharacterized protein COG4076 predicted RNA methylase COG4077 hypothetical protein COG4078 energy-converting hydrogenase Eha subunit H COG4079 hypothetical protein COG4080 SpoU rRNA methylase family enzyme COG4081 hypothetical protein COG4083 exosortase/archaeosortase COG4084 energy-converting hydrogenase A subunit M COG4085 DNA/RNA endonuclease YhcR with UshA esterase domain COG4086 uncharacterized protein YpuA (DUF1002 family) COG4087 soluble P-type ATPase COG4088 tRNA uridine 5-carbamoylmethylation protein Kti12 COG4089 uncharacterized membrane protein COG4090 hypothetical protein COG4091 predicted homoserine dehydrogenase-like protein COG4092 predicted glycosyltransferase involved in capsule biosynthesis COG4093 hypothetical protein COG4094 uncharacterized membrane protein COG4095 uncharacterized protein with PQ loop repeat COG4096 type I site-specific restriction endonuclease COG4097 predicted ferric reductase COG4098 late competence protein required for DNA uptake (superfamily II DNA/RNA helicase) COG4099 predicted peptidase COG4100 cystathionine beta-lyase family protein involved in aluminum resistance COG4101 uncharacterized RmlC-like cupin family protein COG4102 uncharacterized protein (DUF1501 family) COG4103 uncharacterized tellurite resistance protein B-like protein COG4104 uncharacterized Zn-binding protein involved in type VI secretion COG4105 outer membrane protein assembly factor BamD (BamD/ComL family) COG4106 trans-aconitate methyltransferase COG4107 ABC-type phosphonate transport system ATPase subunit COG4108 peptide subunit release factor RF-3 COG4109 predicted transcriptional regulator COG4110 uncharacterized protein involved in tellurium resistance COG4111 hypothetical protein COG4112 predicted NUDIX family phosphoesterase COG4113 predicted nucleic acid-binding protein COG4114 ferric iron reductase protein FhuF COG4115 Txe/YoeB family toxin of Txe-Axe toxin-antitoxin module COG4116 uncharacterized protein YjbK COG4117 thiosulfate reductase cytochrome b subunit COG4118 antitoxin (DNA-binding transcriptional repressor) of toxin-antitoxin stability system COG4119 predicted NUDIX family NTP pyrophosphohydrolase COG4120 ABC-type uncharacterized transport system permease subunit COG4121 tRNA U34 5-methylaminomethyl-2-thiouridine-forming methyltransferase MnmC COG4122 predicted O-methyltransferase YrrM COG4123 tRNA1(Val) A37 N6-methylase TrmN6 COG4124 beta-mannanase COG4125 uncharacterized membrane protein COG4126 Asp/Glu/hydantoin racemase COG4127 predicted Mrr-cat superfamily restriction endonuclease COG4128 zona occludens toxin (predicted ATPase) COG4129 uncharacterized membrane protein YgaE (UPF0421/DUF939 family) COG4130 predicted xylose isomerase-like sugar epimerase COG4132 ABC-type uncharacterized transport system permease subunit COG4133 ABC-type transport system involved in cytochrome c biogenesis ATPase subunit COG4134 ABC-type uncharacterized transport system YnjBCD substrate-binding protein COG4135 ABC-type uncharacterized transport system YnjBCD permease subunit COG4136 ABC-type uncharacterized transport system YnjBCD ATPase subunit COG4137 ABC-type uncharacterized transport system permease subunit COG4138 ABC-type cobalamin transport system ATPase subunit COG4139 ABC-type cobalamin transport system permease subunit COG4143 ABC-type thiamine transport system substrate-binding protein COG4145 Na+/pantothenate symporter COG4146 uncharacterized sodium:solute symporter family permease YidK COG4147 Na+(H+)/acetate symporter ActP COG4148 ABC-type molybdate transport system ATPase subunit COG4149 ABC-type molybdate transport system permease subunit COG4150 ABC-type sulfate transport system substrate-binding protein COG4152 ABC-type uncharacterized transport system ATPase subunit COG4154 L-fucose mutarotase/ribose pyranase (RbsD/FucU family) COG4158 predicted ABC-type sugar transport system permease subunit COG4160 ABC-type arginine/histidine transport system permease subunit COG4161 ABC-type arginine transport system ATPase subunit COG4166 ABC-type oligopeptide transport system substrate-binding subunit COG4167 ABC-type antimicrobial peptide transport system ATPase subunit COG4168 ABC-type antimicrobial peptide transport system permease subunit COG4170 ABC-type antimicrobial peptide transport system ATPase subunit COG4171 ABC-type antimicrobial peptide transport system permease subunit COG4172 ABC-type microcin C transport system duplicated ATPase subunit YejF COG4174 ABC-type microcin C transport system permease subunit YejB COG4175 ABC-type proline/glycine betaine transport system ATPase subunit COG4176 ABC-type proline/glycine betaine transport system permease subunit COG4177 ABC-type branched-subunit amino acid transport system permease subunit COG4178 ABC-type uncharacterized transport system fused permease/ATPase subunit COG4181 predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis ATPase subunit COG4185 predicted ABC-type ATPase COG4186 calcineurin-like phosphoesterase family protein COG4187 arginine utilization protein RocB COG4188 predicted dienelactone hydrolase COG4189 predicted transcriptional regulator COG4190 predicted transcriptional regulator COG4191 C4-dicarboxylate-specific signal transduction histidine kinase COG4192 phosphoglycerate-specific signal transduction histidine kinase COG4193 beta-N-acetylglucosaminidase COG4194 uncharacterized membrane protein COG4195 phage replication-related protein YjqB (UPF0714/DUF867 family) COG4196 uncharacterized protein (DUF2126 family) COG4197 DNA-binding transcriptional regulator YdaS (Cro superfamily) COG4198 uncharacterized protein (DUF1015 family) COG4199 ssDNA-specific exonuclease RecJ COG4200 hypothetical protein COG4206 outer membrane cobalamin receptor COG4208 ABC-type sulfate transport system permease subunit COG4209 ABC-type polysaccharide transport system permease subunit COG4211 ABC-type glucose/galactose transport system permease subunit COG4213 ABC-type xylose transport system substrate-binding protein COG4214 ABC-type xylose transport system permease subunit COG4215 ABC-type arginine transport system permease subunit COG4218 tetrahydromethanopterin S-methyltransferase subunit F COG4219 beta-lactamase regulating signal transducer with metallopeptidase domain COG4220 phage terminase Nu1 subunit (DNA packaging protein) COG4221 NADP-dependent 3-hydroxy acid dehydrogenase YdfG COG4222 hypothetical protein COG4223 hypothetical protein COG4224 uncharacterized protein YnzC (UPF0291/DUF896 family) COG4225 rhamnogalacturonyl hydrolase YesR COG4226 predicted HicB family RNase H-like nuclease COG4227 antirestriction protein ArdC COG4228 prophage DNA circulation protein COG4229 methionine salvage enolase-phosphatase E1 COG4230 delta 1-pyrroline-5-carboxylate dehydrogenase COG4231 TPP-dependent indolepyruvate ferredoxin oxidoreductase alpha subunit COG4232 thiol:disulfide interchange protein COG4233 DsbC/DsbD-like thiol-disulfide interchange protein COG4235 cytochrome c-type biogenesis protein CcmH/NrfG COG4237 hydrogenase-4 membrane subunit HyfE COG4238 outer membrane murein-binding lipoprotein Lpp COG4239 ABC-type microcin C transport system permease subunit YejE COG4240 pantothenate kinase-related protein Tda10 COG4241 uncharacterized protein YybS (DUF2232 family) COG4242 cyanophycinase-like exopeptidase COG4243 uncharacterized membrane protein COG4244 uncharacterized membrane protein COG4245 uncharacterized protein YegL COG4246 hypothetical protein COG4247 myo-inositol-hexaphosphate 3-phosphohydrolase COG4248 DNA-binding helix-hairpin-helix protein with protein kinase domain COG4249 uncharacterized caspase-like protein COG4250 DICT domain-containing protein COG4251 light-regulated signal transduction histidine kinase (bacteriophytochrome) COG4252 CHASE2 domain-containing sensor protein COG4253 uncharacterized protein (DUF2345 family) COG4254 hypothetical protein COG4255 hypothetical protein COG4256 hemin uptake protein HemP COG4257 streptogramin lyase COG4258 predicted exporter COG4259 hypothetical protein COG4260 membrane protease subunit (stomatin/prohibitin family) COG4261 predicted LPLAT superfamily acyltransferase COG4262 predicted membrane-bound spermidine synthase COG4263 nitrous oxide reductase COG4264 siderophore synthetase component COG4266 allantoicase COG4267 uncharacterized membrane protein COG4268 5-methylcytosine-specific restriction endonuclease McrBC regulatory subunit McrC COG4269 uncharacterized membrane protein YjgN (DUF898 family) COG4270 uncharacterized membrane protein COG4271 predicted nucleotide-binding protein COG4272 uncharacterized membrane protein COG4273 uncharacterized metal-binding protein COG4274 uncharacterized protein with GYD domain COG4275 hypothetical protein COG4276 ligand-binding SRPBCC domain-containing protein COG4277 predicted DNA-binding helix-hairpin-helix protein COG4278 hypothetical protein COG4279 uncharacterized Zn finger protein COG4280 uncharacterized membrane protein COG4281 acyl-CoA-binding protein COG4282 cell wall assembly regulator SMI1 COG4283 hypothetical protein COG4284 UDP-N-acetylglucosamine pyrophosphorylase COG4285 glutamine amidotransferase-like uncharacterized protein COG4286 uncharacterized UPF0160 family protein COG4287 PhoPQ-activated pathogenicity-related protein COG4288 hypothetical protein COG4289 hypothetical protein COG4290 guanyl-specific ribonuclease Sa COG4291 uncharacterized membrane protein COG4292 low temperature requirement protein LtrA COG4293 hypothetical protein COG4294 UV DNA damage repair endonuclease COG4295 hypothetical protein COG4296 hypothetical protein COG4297 uncharacterized protein YjlB COG4298 hypothetical protein COG4299 predicted acyltransferase COG4300 cadmium resistance protein CadD (predicted permease) COG4301 uncharacterized SAM-dependent methyltransferase COG4302 ethanolamine ammonia-lyase small subunit COG4303 ethanolamine ammonia-lyase large subunit COG4304 hypothetical protein COG4305 expansin (peptidoglycan-binding protein) COG4306 hypothetical protein COG4307 hypothetical protein COG4308 limonene-1,2-epoxide hydrolase COG4309 uncharacterized protein (DUF2249 family) COG4310 aminopeptidase-like protein COG4311 sarcosine oxidase delta subunit COG4312 predicted dithiol-disulfide oxidoreductase (DUF899 family) COG4313 hypothetical protein COG4314 nitrous oxide reductase accessory protein NosL COG4315 predicted lipoprotein with Yx(FWY)xxD motif COG4316 hypothetical protein COG4317 xanthosine utilization system XapX-like protein COG4318 hypothetical protein COG4319 ketosteroid isomerase-like protein COG4320 uncharacterized protein (DUF2252 family) COG4321 predicted DNA-binding ribbon-helix-helix protein COG4322 hypothetical protein COG4323 hypothetical protein COG4324 predicted aminopeptidase COG4325 uncharacterized membrane protein COG4326 sporulation-control protein spo0M COG4327 uncharacterized membrane protein COG4328 predicted RNase H-like nuclease COG4329 uncharacterized membrane protein COG4330 uncharacterized membrane protein COG4331 uncharacterized membrane protein COG4332 hypothetical protein COG4333 hypothetical protein COG4334 hypothetical protein COG4335 3-methyladenine DNA glycosylase AlkC COG4336 uncharacterized protein YcsI (UPF0317 family) COG4337 hypothetical protein COG4338 hypothetical protein COG4339 predicted metal-dependent HD superfamily phosphohydrolase COG4340 hypothetical protein COG4341 predicted HD phosphohydrolase COG4342 intergrase/recombinase COG4343 CRISPR/Cas system-associated exonuclease Cas4 (RecB family) COG4344 predicted transcriptional regulator COG4345 hypothetical protein COG4346 predicted membrane-bound dolichyl-phosphate-mannose-protein mannosyltransferase COG4347 uncharacterized membrane protein YpjA COG4352 ribosomal protein L13E COG4353 hypothetical protein COG4354 uncharacterized protein (DUF608 family) COG4357 uncharacterized CHY-type Zn-finger protein COG4359 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase COG4360 ATP adenylyltransferase/5',5'''-P-1,P-4-tetraphosphate phosphorylase II COG4362 nitric oxide synthase oxygenase domain/subunit COG4365 uncharacterized protein YllA (UPF0747 family) COG4367 hypothetical protein COG4370 hypothetical protein COG4371 uncharacterized membrane protein COG4372 uncharacterized protein (DUF3084 family) COG4373 phage FluMu gp28-like protein COG4374 PIN domain nuclease of toxin-antitoxin system COG4377 uncharacterized membrane protein YhfC COG4378 hypothetical protein COG4379 prophage tail gpP-like protein COG4380 hypothetical protein COG4381 phage gp46-like protein COG4382 phage gp16-like protein COG4383 phage gp29-like protein COG4384 phage gp45-like COG4385 P2-related tail formation protein COG4386 phage tail sheath gpL-like COG4387 phage gp36-like protein COG4388 phage I-like protein COG4389 site-specific recombinase COG4390 hypothetical protein COG4391 uncharacterized Zn-finger protein COG4392 branched-subunit amino acid transport protein COG4393 uncharacterized membrane protein COG4394 hypothetical protein COG4395 predicted lipid-binding transport protein (Tim44 family) COG4396 phage host-nuclease inhibitor protein Gam COG4397 phage major head subunit gpT-like protein COG4398 small ligand-binding sensory domain FIST COG4399 uncharacterized membrane protein YheB (UPF0754 family) COG4401 chorismate mutase COG4402 hypothetical protein COG4403 lantibiotic modifying enzyme COG4405 uncharacterized protein YhfF COG4408 hypothetical protein COG4409 Neuraminidase (sialidase) COG4412 bacillopeptidase F (M6 metalloprotease family) COG4413 urea transporter COG4416 phage FluMu protein Com COG4420 uncharacterized membrane protein COG4421 capsular polysaccharide biosynthesis protein COG4422 protein gp37 COG4423 hypothetical protein COG4424 LPS sulfotransferase NodH COG4425 uncharacterized membrane protein COG4427 hypothetical protein COG4430 uncharacterized protein YdeI (YjbR/CyaY-like superfamily) COG4443 hypothetical protein COG4445 tRNA isopentenyl-2-thiomethyl-A-37 hydroxylase MiaE COG4446 uncharacterized protein (DUF1499 family) COG4447 photosystem II stability/assembly factor-like uncharacterized protein COG4448 L-asparaginase II COG4449 predicted Abi (CAAX) family protease COG4451 ribulose bisphosphate carboxylase small subunit COG4452 inner membrane protein involved in colicin E2 resistance COG4453 uncharacterized protein (DUF1778 family) COG4454 uncharacterized cupredoxin-like copper-binding protein COG4455 protein involved in temperature-dependent protein secretion COG4456 virulence-associated protein VagC COG4457 hypothetical protein COG4458 hypothetical protein COG4459 nitrate reductase NapE component COG4460 hypothetical protein COG4461 uncharacterized protein COG4463 transcriptional regulator CtsR COG4464 tyrosine-protein phosphatase YwqE COG4465 GTP-sensing pleiotropic transcriptional regulator CodY COG4466 uncharacterized protein Veg COG4467 regulator of replication initiation timing COG4468 galactose-1-phosphate uridylyltransferase COG4469 competence CoiA-like predicted nuclease COG4470 uncharacterized protein YutD COG4471 uncharacterized protein YlbG (UPF0298 family) COG4472 uncharacterized protein (UPF0297 family) COG4473 predicted ABC-type exoprotein transport system permease subunit COG4474 uncharacterized phage-like protein YoqJ COG4475 uncharacterized protein YwlG (UPF0340 family) COG4476 uncharacterized protein YktA (UPF0223 family) COG4477 septation ring formation regulator EzrA COG4478 uncharacterized membrane protein COG4479 uncharacterized protein YozE (UPF0346 family) COG4481 hypothetical protein COG4483 uncharacterized protein YqgQ COG4485 uncharacterized membrane protein YfhO COG4487 hypothetical protein COG4492 ACT domain-containing protein COG4493 uncharacterized protein YktB (UPF0637 family) COG4495 hypothetical protein COG4496 uncharacterized protein YerC COG4499 uncharacterized membrane protein YukC COG4502 5'(3')-deoxyribonucleotidase COG4506 uncharacterized beta-barrel protein YwiB (DUF1934 family) COG4508 dimeric dUTPase (all-alpha-NTP-PPase superfamily) COG4509 hypothetical protein COG4512 accessory gene regulator protein AgrB COG4517 hypothetical protein COG4518 phage FluMu protein gp41 COG4519 hypothetical protein COG4520 surface antigen COG4521 ABC-type taurine transport system substrate-binding protein COG4525 ABC-type taurine transport system ATPase subunit COG4529 uncharacterized NAD(P)/FAD-binding protein YdhS COG4530 hypothetical protein COG4531 ABC-type Zn2+ transport system substrate-binding protein/surface adhesin COG4533 MarR-like DNA-binding transcriptional regulator SgrR of sgrS sRNA COG4535 Mg2+/Co2+ transporter CorC COG4536 Mg2+/Co2+ transporter CorB COG4537 competence protein ComGC COG4538 hypothetical protein COG4539 uncharacterized membrane protein YGL010W COG4540 phage baseplate assembly protein gpV COG4541 uncharacterized membrane protein COG4542 uncharacterized protein involved in propanediol utilization COG4544 hypothetical protein COG4545 glutaredoxin-related protein COG4547 cobalamin biosynthesis protein CobT COG4548 nitric oxide reductase activation protein COG4549 uncharacterized protein YcnI COG4550 cell fate (sporulation/competence/biofilm development) regulator YmcA (YheA/YmcA/DUF963 family) COG4551 predicted protein tyrosine phosphatase COG4552 predicted acetyltransferase COG4553 poly-beta-hydroxyalkanoate depolymerase COG4555 ABC-type Na+ transport system ATPase subunit NatA COG4558 ABC-type hemin transport system substrate-binding protein COG4559 ABC-type hemin transport system ATPase subunit COG4564 signal transduction histidine kinase COG4565 response regulator of citrate/malate metabolism COG4566 FixJ family two-component response regulator COG4567 ActR/RegA family two-component response regulator COG4568 transcriptional antiterminator Rof (Rho-off) COG4569 acetaldehyde dehydrogenase (acetylating) COG4570 Holliday junction resolvase RusA-like endonuclease COG4571 outer membrane protease COG4572 cation transport regulator ChaB COG4573 tagatose-1,6-bisphosphate aldolase non-catalytic subunit AgaZ/GatZ COG4574 serine protease inhibitor ecotin COG4575 ElaB/YqjD/DUF883 family membrane-anchored ribosome-binding protein COG4576 microcompartment protein CcmK/EutM COG4577 microcompartment protein CcmL/EutN COG4578 DNA-binding transcriptional regulator of glucitol operon COG4579 isocitrate dehydrogenase kinase/phosphatase COG4580 maltoporin COG4581 superfamily II RNA helicase COG4582 cell division FtsZ-interacting protein ZapD COG4583 sarcosine oxidase gamma subunit COG4584 transposase COG4585 signal transduction histidine kinase COG4586 ABC-type uncharacterized transport system ATPase subunit COG4587 ABC-type uncharacterized transport system permease subunit COG4588 accessory colonization factor AcfC COG4589 predicted CDP-diglyceride synthetase/phosphatidate cytidylyltransferase COG4590 ABC-type uncharacterized transport system permease subunit COG4591 ABC-type lipoprotein release transport system permease subunit COG4592 ABC-type Fe2+-enterobactin transport system substrate-binding protein COG4594 ABC-type Fe3+-citrate transport system substrate-binding protein COG4597 ABC-type amino acid transport system permease subunit COG4598 ABC-type histidine transport system ATPase subunit COG4603 ABC-type uncharacterized transport system permease subunit COG4604 ABC-type enterochelin transport system ATPase subunit COG4605 ABC-type enterochelin transport system permease subunit COG4606 ABC-type enterochelin transport system permease subunit COG4607 ABC-type enterochelin transport system substrate-binding protein COG4608 ABC-type oligopeptide transport system ATPase subunit COG4615 ABC-type siderophore export system fused ATPase/permease subunit COG4618 ABC-type protease/lipase transport system fused ATPase/permease subunit COG4619 ABC-type iron transport system FetAB ATPase subunit COG4623 membrane-bound lytic murein transglycosylase MltF COG4624 iron only hydrogenase large subunit-like protein COG4625 uncharacterized protein with beta-barrel porin domain COG4626 phage terminase large subunit-like protein COG4627 predicted SAM-dependent methyltransferase COG4628 uncharacterized protein (DUF2132 family) COG4630 xanthine dehydrogenase iron-sulfur cluster and FAD-binding subunit A COG4631 xanthine dehydrogenase molybdopterin-binding subunit B COG4632 exopolysaccharide biosynthesis protein COG4633 plastocyanin domain-containing protein COG4634 predicted nuclease of predicted toxin-antitoxin system COG4635 menaquinone-dependent protoporphyrinogen IX oxidase COG4636 Uma2 family endonuclease COG4637 predicted ATPase COG4638 phenylpropionate dioxygenase-like ring-hydroxylating dioxygenase large terminal subunit COG4639 predicted kinase COG4640 uncharacterized membrane protein YvbJ COG4641 spore maturation protein CgeB COG4642 hypothetical protein COG4643 phage/plasmid primase-like uncharacterized protein COG4644 TnpA family transposase COG4645 hypothetical protein COG4646 N12 class adenine-specific DNA methylase COG4647 acetone carboxylase gamma subunit COG4648 uncharacterized membrane protein COG4649 hypothetical protein COG4650 sigma54-dependent transcription regulator COG4651 predicted Kef-type K+ transport protein COG4652 hypothetical protein COG4653 predicted phage gp36 major capsid-like protein COG4654 cytochrome c551/c552 COG4655 uncharacterized membrane protein COG4656 Na+-translocating ferredoxin:NAD+ oxidoreductase RnfC subunit COG4657 Na+-translocating ferredoxin:NAD+ oxidoreductase RnfA subunit COG4658 Na+-translocating ferredoxin:NAD+ oxidoreductase RnfD subunit COG4659 Na+-translocating ferredoxin:NAD+ oxidoreductase RnfG subunit COG4660 Na+-translocating ferredoxin:NAD+ oxidoreductase RnfE subunit COG4662 ABC-type tungstate transport system substrate-binding protein COG4663 TRAP-type mannitol/chloroaromatic compound transport system substrate-binding protein COG4664 TRAP-type mannitol/chloroaromatic compound transport system permease large subunit COG4665 TRAP-type mannitol/chloroaromatic compound transport system permease small subunit COG4666 TRAP-type uncharacterized transport system fused permease subunit COG4667 predicted patatin/cPLA2 family phospholipase COG4668 mannitol/fructose-specific phosphotransferase system IIA component COG4669 type III secretory pathway lipoprotein EscJ COG4670 acyl CoA:acetate/3-ketoacid CoA transferase COG4671 predicted glycosyltransferase COG4672 phage-related protein COG4674 ABC-type uncharacterized transport system ATPase subunit COG4675 microcystin-dependent protein COG4676 uncharacterized protein YfaP (DUF2135 family) COG4677 pectin methylesterase-like acyl-CoA thioesterase COG4678 muramidase (phage lysozyme) COG4679 phage-related protein COG4680 mRNA-degrading endonuclease HigB of HigAB toxin-antitoxin module COG4681 uncharacterized protein YaeQ COG4682 uncharacterized membrane protein YiaA COG4683 hypothetical protein COG4684 uncharacterized membrane protein COG4685 uncharacterized protein YfaA (DUF2138 family) COG4687 hypothetical protein COG4688 hypothetical protein COG4689 acetoacetate decarboxylase COG4690 dipeptidase COG4691 plasmid stability protein COG4692 predicted neuraminidase COG4693 NAD-dependent oxidoreductase involved in siderophore biosynthesis COG4694 wobble nucleotide-excising tRNase COG4695 phage portal protein BeeE COG4696 predicted HAD superfamily Cof-like phosphohydrolase COG4697 hypothetical protein COG4698 uncharacterized protein YpmS COG4699 hypothetical protein COG4700 hypothetical protein COG4701 hypothetical protein COG4702 uncharacterized protein (UPF0303 family) COG4703 uncharacterized protein YkuJ COG4704 uncharacterized protein (DUF2141 family) COG4705 uncharacterized membrane-anchored protein COG4706 predicted hotdog family 3-hydroxylacyl-ACP dehydratase COG4707 phage pi2 protein 07 COG4708 uncharacterized membrane protein COG4709 uncharacterized membrane protein COG4710 predicted DNA-binding protein COG4711 uncharacterized membrane protein COG4712 hypothetical protein COG4713 uncharacterized membrane protein COG4714 uncharacterized membrane-anchored protein COG4715 uncharacterized Zn finger protein COG4716 myosin-crossreactive antigen COG4717 uncharacterized protein YhaN COG4718 phage-related protein COG4719 hypothetical protein COG4720 uncharacterized membrane protein COG4721 ABC-type thiamin/hydroxymethylpyrimidine transport system permease subunit COG4722 phage-related protein COG4723 predicted phage tail protein COG4724 endo-beta-N-acetylglucosaminidase D COG4725 N6-adenosine-specific RNA methylase IME4 COG4726 Tfp pilus assembly protein PilX COG4727 hypothetical protein COG4728 hypothetical protein COG4729 hypothetical protein COG4731 uncharacterized protein (DUF2147 family) COG4732 predicted membrane protein COG4733 predicted phage tail protein COG4734 antirestriction protein COG4735 uncharacterized protein YaaW (UPF0174 family) COG4736 cbb3-type cytochrome oxidase subunit 3 COG4737 hypothetical protein COG4738 predicted transcriptional regulator COG4739 uncharacterized ferredoxin-like protein COG4740 predicted metalloprotease COG4741 predicted Holliday junction resolvase-like endonuclease COG4742 predicted transcriptional regulator COG4743 uncharacterized membrane protein COG4744 hypothetical protein COG4745 predicted membrane-bound mannosyltransferase COG4746 hypothetical protein COG4747 hypothetical protein COG4748 hypothetical protein COG4749 hypothetical protein COG4750 CTP:phosphocholine cytidylyltransferase-like protein COG4752 hypothetical protein COG4753 YesN/AraC family two-component response regulator COG4754 hypothetical protein COG4755 hypothetical protein COG4756 predicted cation transporter COG4757 predicted alpha/beta hydrolase COG4758 predicted membrane protein COG4759 hypothetical protein COG4760 uncharacterized YccA/Bax inhibitor family protein COG4762 uncharacterized protein (UPF0548 family) COG4763 uncharacterized membrane protein YcfT COG4764 hypothetical protein COG4765 hypothetical protein COG4766 ethanolamine utilization protein EutQ (cupin superfamily) COG4767 glycopeptide antibiotics resistance protein COG4768 uncharacterized protein YoxC COG4769 uncharacterized membrane protein COG4770 acetyl/propionyl-CoA carboxylase alpha subunit COG4771 outer membrane receptor for ferrienterochelin and colicin COG4772 outer membrane receptor for Fe3+-dicitrate COG4773 outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid COG4774 outer membrane receptor for monomeric catechols COG4775 outer membrane protein assembly factor BamA COG4776 exoribonuclease II COG4778 alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL COG4779 ABC-type enterobactin transport system permease subunit COG4781 membrane-anchored glycerophosphoryl diester phosphodiesterase (GDPDase) COG4782 esterase/lipase superfamily enzyme COG4783 predicted Zn-dependent protease COG4784 predicted Zn-dependent protease COG4785 lipoprotein NlpI COG4786 flagellar basal body rod protein FlgG COG4787 flagellar basal body rod protein FlgF COG4789 type III secretory pathway component EscV COG4790 type III secretory pathway component EscR COG4791 type III secretory pathway component EscT COG4792 type III secretory pathway component EscU COG4794 type III secretory pathway component EscS COG4795 type II secretory pathway component PulJ COG4796 type II secretory pathway component HofQ COG4797 methyltransferase-like protein COG4798 predicted methyltransferase COG4799 acetyl-CoA carboxylase carboxyltransferase component COG4800 predicted transcriptional regulator COG4801 predicted acyltransferase (DUF342 family) COG4802 ferredoxin-thioredoxin reductase catalytic subunit COG4803 uncharacterized membrane protein COG4804 predicted nuclease of restriction endonuclease-like (RecB) superfamily COG4805 uncharacterized protein (DUF885 family) COG4806 L-rhamnose isomerase COG4807 uncharacterized protein YehS (DUF1456 family) COG4808 uncharacterized lipoprotein YehR (DUF1307 family) COG4809 ADP-dependent phosphofructokinase/glucokinase COG4810 ethanolamine utilization microcompartment shell protein EutS COG4811 uncharacterized membrane protein YobD (UPF0266 family) COG4812 ethanolamine utilization cobalamin adenosyltransferase COG4813 trehalose utilization protein COG4814 uncharacterized alpha/beta hydrolase family protein COG4815 hypothetical protein COG4816 ethanolamine utilization microcompartment shell protein EutL COG4817 DNA-binding ferritin-like protein (Dps family) COG4818 uncharacterized membrane protein COG4819 ethanolamine utilization protein EutA (predicted chaperonin) COG4820 Ethanolamine utilization protein EutJ (predicted chaperonin) COG4821 uncharacterized phosphosugar-binding protein COG4822 cobalamin biosynthesis Co2+ chelatase CbiK COG4823 abortive infection bacteriophage resistance protein COG4824 phage-related holin COG4825 uncharacterized membrane-anchored protein COG4826 serine protease inhibitor COG4827 predicted transporter COG4828 uncharacterized membrane protein COG4829 muconolactone delta-isomerase COG4830 ribosomal protein S26 COG4831 roadblock/LC7 domain-containing protein COG4832 hypothetical protein COG4833 predicted alpha-1,6-mannanase (GH76 family) COG4834 hypothetical protein COG4835 hypothetical protein COG4836 uncharacterized membrane protein YwzB COG4837 disulfide oxidoreductase YuzD COG4838 uncharacterized protein YlaN (UPF0358 family) COG4839 cell division protein FtsL COG4840 uncharacterized protein YfkK (UPF0435 family) COG4841 uncharacterized protein YneR COG4842 uncharacterized protein YukE COG4843 uncharacterized protein YebE (UPF0316 family) COG4844 uncharacterized protein YuzB (UPF0349 family) COG4845 chloramphenicol O-acetyltransferase COG4846 membrane protein CcdC involved in cytochrome C biogenesis COG4847 hypothetical protein COG4848 uncharacterized protein YtpQ (UPF0354 family) COG4849 predicted nucleotidyltransferase COG4850 phosphatidate phosphatase APP1 COG4851 protein involved in sex pheromone biosynthesis COG4852 uncharacterized membrane protein COG4853 regulatory protein YycI of two-component signal transduction system YycFG COG4854 uncharacterized membrane protein COG4855 hypothetical protein COG4856 YbbR domain-containing protein COG4857 5-methylthioribose kinase COG4858 uncharacterized membrane-anchored protein COG4859 hypothetical protein COG4860 predicted DNA-binding ArsR family transcriptional regulator COG4861 hypothetical protein COG4862 negative regulator of genetic competence, sporulation and motility COG4863 regulatory protein YycH of two-component signal transduction system YycFG COG4864 uncharacterized protein YqfA (UPF0365 family) COG4865 glutamate mutase epsilon subunit COG4866 hypothetical protein COG4867 uncharacterized protein with von Willebrand factor type A (vWA) domain COG4868 uncharacterized protein (UPF0371 family) COG4869 propanediol utilization protein COG4870 C1A family cysteine protease COG4871 ArsR family metal-binding transcriptional regulator COG4872 uncharacterized membrane protein COG4873 uncharacterized protein YkvS COG4874 hypothetical protein COG4875 hypothetical protein COG4876 uncharacterized protein YdaT COG4877 hypothetical protein COG4878 hypothetical protein COG4879 hypothetical protein COG4880 uncharacterized secreted protein with C-terminal beta-propeller domain COG4881 predicted membrane protein COG4882 Iap family predicted aminopeptidase COG4883 hypothetical protein COG4884 uncharacterized protein YfeS COG4885 hypothetical protein COG4886 Leucine-rich repeat (LRR) protein COG4887 uncharacterized metal-binding protein COG4888 transcription elongation factor Elf1 COG4889 predicted helicase COG4890 predicted outer membrane lipoprotein COG4891 hypothetical protein COG4892 predicted heme/steroid binding protein COG4893 hypothetical protein COG4894 uncharacterized protein YxjI COG4895 uncharacterized protein YwbE COG4896 uncharacterized protein YlaI COG4897 general stress protein CsbA COG4898 hypothetical protein COG4899 hypothetical protein COG4900 predicted metallopeptidase COG4901 ribosomal protein S25 COG4902 hypothetical protein COG4903 competence transcription factor ComK COG4904 hypothetical protein COG4905 uncharacterized membrane protein COG4906 uncharacterized membrane protein COG4907 uncharacterized membrane protein COG4908 NRPS condensation-like uncharacterized protein COG4909 propanediol dehydratase large subunit COG4910 propanediol dehydratase small subunit COG4911 hypothetical protein COG4912 3-methyladenine DNA glycosylase AlkD COG4913 uncharacterized protein YPO0396 COG4914 predicted nucleotidyltransferase COG4915 5-bromo-4-chloroindolyl phosphate hydrolysis protein COG4916 hypothetical protein COG4917 ethanolamine utilization protein EutP (predicted NTPase) COG4918 uncharacterized protein YqkB COG4919 ribosomal protein S30 COG4920 uncharacterized membrane protein COG4921 hypothetical protein COG4922 predicted SnoaL-like aldol condensation-catalyzing enzyme COG4923 predicted RNase H-like nuclease COG4924 hypothetical protein COG4925 hypothetical protein COG4926 phage-related protein COG4927 predicted choloylglycine hydrolase COG4928 predicted KAP-like P-loop ATPase COG4929 uncharacterized membrane-anchored protein COG4930 predicted ATP-dependent Lon-type protease COG4932 uncharacterized surface anchored protein COG4933 predicted transcriptional regulator COG4934 subtilase family serine protease COG4935 subtilisin-like proprotein convertase family protein COG4936 ligand-binding sensor protein COG4937 ferredoxin-fold anticodon binding domain-containing protein COG4938 predicted ATPase COG4939 major membrane immunogen (membrane-anchored lipoprotein) COG4940 competence protein ComGF COG4941 predicted RNA polymerase sigma factor COG4942 septal ring factor EnvC (AmiA/AmiB activator) COG4943 sensor c-di-GMP phosphodiesterase-like protein COG4944 hypothetical protein COG4945 carbohydrate-binding DOMON domain-containing protein COG4946 tricorn protease-like protein COG4947 esterase/lipase superfamily enzyme COG4948 L-alanine-DL-glutamate epimerase-like enolase superfamily enzyme COG4949 uncharacterized membrane-anchored protein COG4950 uncharacterized protein YciW COG4951 hypothetical protein COG4952 L-rhamnose isomerase COG4953 membrane carboxypeptidase/penicillin-binding protein PbpC COG4954 hypothetical protein COG4955 uncharacterized protein YpbB COG4956 uncharacterized protein YacL COG4957 predicted transcriptional regulator COG4959 type IV secretory pathway protease TraF COG4960 Flp pilus assembly protein protease CpaA COG4961 Flp pilus assembly protein TadG COG4962 Flp pilus assembly CpaF family ATPase COG4963 Flp pilus assembly CpaE family ATPase COG4964 Flp pilus assembly secretin CpaC COG4965 Flp pilus assembly protein TadB COG4966 Tfp pilus assembly protein PilW COG4967 Tfp pilus assembly protein PilV COG4968 Tfp pilus assembly protein PilE COG4969 Tfp pilus assembly major pilin PilA COG4970 Tfp pilus assembly protein FimT COG4972 Tfp pilus assembly PilM family ATPase COG4973 site-specific recombinase XerC COG4974 site-specific recombinase XerD COG4975 glucose uptake protein GlcU COG4976 predicted TPR repeat methyltransferase COG4977 transcriptional regulator GlxA family with amidase domain COG4978 effector-binding domain-containing protein COG4980 gas vesicle protein COG4981 enoyl reductase-like protein COG4982 3-oxoacyl-ACP reductase-like protein COG4983 primase-polymerase (primpol)-like protein COG4984 uncharacterized membrane protein COG4985 ABC-type phosphate transport system auxiliary subunit COG4986 ABC-type anion transport system duplicated permease subunit COG4987 ABC-type transport system involved in cytochrome bd biosynthesis fused ATPase/permease subunit COG4988 ABC-type transport system involved in cytochrome bd biosynthesis fused ATPase/permease subunit COG4989 predicted oxidoreductase COG4990 uncharacterized protein YvpB COG4991 uncharacterized protein YraI COG4992 acetylornithine/succinyldiaminopimelate/putrescine aminotransferase COG4993 glucose dehydrogenase COG4994 hypothetical protein COG4995 CHAT domain-containing protein COG4996 predicted phosphatase COG4997 predicted house-cleaning noncanonical NTP pyrophosphatase (MazG superfamily) COG4998 predicted RecB family endonuclease COG4999 BarA-like signal transduction histidine kinase COG5000 nitrogen fixation/metabolism regulation signal transduction histidine kinase COG5001 predicted signal transduction protein with EAL and GGDEF domain COG5002 signal transduction histidine kinase COG5003 phage gp37-like protein COG5004 phage tail protein X COG5005 phage gpG-like protein COG5006 threonine/homoserine efflux transporter RhtA COG5007 acid stress-induced BolA-like protein IbaG/YrbA COG5008 Tfp pilus assembly ATPase PilU COG5009 membrane carboxypeptidase/penicillin-binding protein COG5010 Flp pilus assembly protein TadD COG5011 uncharacterized protein (DUF2344 family) COG5012 methanogenic corrinoid protein MtbC1 COG5013 nitrate reductase alpha subunit COG5014 uncharacterized Fe-S cluster-containing radical SAM superfamily protein COG5015 uncharacterized pyridoxamine 5'-phosphate oxidase family protein COG5016 pyruvate/oxaloacetate carboxyltransferase COG5017 UDP-N-acetylglucosamine transferase subunit ALG13 COG5018 inhibitor of KinA sporulation pathway (predicted exonuclease) COG5019 septin family protein COG5022 myosin heavy subunit COG5026 hexokinase COG5029 prenyltransferase beta subunit COG5031 ubiquinone biosynthesis protein Coq4 COG5032 phosphatidylinositol kinase/protein kinase (PI-3 family) COG5033 transcription initiation factor IIF auxiliary subunit COG5036 SPX domain protein involved in polyphosphate accumulation COG5038 Ca2+-dependent lipid-binding protein COG5039 exopolysaccharide biosynthesis predicted pyruvyltransferase EpsI COG5042 purine nucleoside permease COG5044 RAB protein geranylgeranyltransferase component A COG5048 uncharacterized Zn-finger protein COG5049 5'-3' exonuclease COG5055 recombination DNA repair RAD52 pathway protein COG5074 t-SNARE complex subunit (syntaxin) COG5078 ubiquitin-protein ligase COG5083 phosphatidate phosphatase PAH1 COG5096 vesicle coat complex subunit COG5108 DNA-directed RNA polymerase COG5119 uncharacterized ParB-like nuclease family protein COG5126 Ca2+-binding EF-hand superfamily protein COG5135 hypothetical protein COG5146 pantothenate kinase COG5153 putative lipase involved disintegration of autophagic bodies COG5160 Ulp1 family protease COG5164 transcription elongation factor COG5180 PAB1-binding protein PBP1 COG5183 E3 ubiquitin-protein ligase DOA10 COG5184 alpha-tubulin suppressor-like RCC1 family protein COG5185 SMC interacting uncharacterized protein involved in chromosome segregation COG5186 poly(A) polymerase Pap1 COG5190 TFIIF-interacting CTD phosphatase-like protein COG5206 glycosylphosphatidylinositol transamidase (GPIT) subunit GPI8 COG5207 uncharacterized UBP type Zn finger protein COG5212 cAMP phosphodiesterase COG5238 Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport COG5239 mRNA deadenylase 3'-5' endonuclease subunit Ccr4 COG5244 dynactin complex subunit COG5255 hypothetical protein COG5256 translation elongation factor EF-1alpha COG5257 translation initiation factor 2 gamma subunit (eIF-2gamma) COG5258 GTPase COG5260 DNA polymerase sigma COG5263 glucan-binding YG repeat protein COG5265 ABC-type transport system involved in Fe-S cluster assembly fused permease/ATPase subunit COG5266 uncharacterized GH25 family protein COG5267 uncharacterized protein (DUF1800 family) COG5268 type IV secretory pathway TrbD component COG5270 predicted RNA-binding protein with PUA domain COG5271 midasin (ATPase involved in ribosome maturation) COG5272 ubiquitin COG5274 cytochrome b involved in lipid metabolism COG5275 BRCT domain type II-containing protein COG5276 hypothetical protein COG5277 actin-related protein COG5278 CHASE3 domain sensor protein COG5279 transglutaminase/protease-like cytokinesis protein 3 COG5280 phage-related minor tail protein COG5281 phage-related minor tail protein COG5282 uncharacterized protein (DUF2342 family) COG5283 phage-related tail protein COG5285 ectoine hydroxylase-related dioxygenase (phytanoyl-CoA dioxygenase family) COG5293 uncharacterized protein YydD (DUF2326 family) COG5294 uncharacterized protein YxeA COG5295 autotransporter adhesin COG5297 cellulase/cellobiase CelA1 COG5298 uncharacterized protein YdaL COG5301 phage-related tail fiber protein COG5302 post-segregation antitoxin (ccd killing protein) COG5304 predicted DNA binding CopG/RHH family protein COG5305 uncharacterized membrane protein COG5306 hypothetical protein COG5307 Sec7-like guanine-nucleotide exchange factor COG5309 exo-beta-1,3-glucanase (GH17 family) COG5310 homospermidine synthase COG5314 conjugal transfer/entry exclusion protein COG5316 hypothetical protein COG5317 hypothetical protein COG5319 hypothetical protein COG5321 hypothetical protein COG5322 predicted amino acid dehydrogenase COG5323 phage terminase large subunit-like protein COG5324 tRNA splicing ligase COG5328 uncharacterized protein (UPF0262 family) COG5330 uncharacterized protein (DUF2336 family) COG5331 hypothetical protein COG5336 F0F1-type ATP synthase assembly protein I COG5337 spore coat protein CotH COG5338 hypothetical protein COG5339 uncharacterized protein YdgA (DUF945 family) COG5340 predicted transcriptional regulator of viral defense system COG5341 hypothetical protein COG5342 invasion protein IalB COG5343 anti-sigma-K factor RskA COG5345 hypothetical protein COG5346 uncharacterized membrane protein COG5349 uncharacterized protein (DUF983 family) COG5350 predicted protein tyrosine phosphatase COG5351 hypothetical protein COG5352 hypothetical protein COG5353 uncharacterized protein YpmB COG5354 uncharacterized protein with WD repeat COG5360 uncharacterized heparinase superfamily protein COG5361 hypothetical protein COG5362 phage terminase large subunit-like protein COG5368 hypothetical protein COG5371 Golgi nucleoside diphosphatase COG5373 uncharacterized membrane protein COG5375 hypothetical protein COG5377 predicted phage-related endonuclease COG5378 predicted nucleic acid-binding protein COG5379 S-adenosylmethionine:diacylglycerol 3-amino-3-carboxypropyl transferase COG5380 lipase chaperone LimK COG5381 hypothetical protein COG5383 uncharacterized glyoxalase superfamily metalloenzyme YdcJ COG5384 U3 small nucleolar ribonucleoprotein component COG5385 hypothetical protein COG5386 heme-binding NEAT domain protein COG5387 chaperone required for assembly of F1-ATPase COG5388 hypothetical protein COG5389 hypothetical protein COG5393 uncharacterized membrane protein YqjE COG5394 polyhydroxyalkanoate synthesis regulator protein COG5395 uncharacterized membrane protein COG5397 hypothetical protein COG5398 heme oxygenase COG5399 hypothetical protein COG5400 hypothetical protein COG5401 spore germination protein GerM COG5402 hypothetical protein COG5403 hypothetical protein COG5404 cell division inhibitor SulA COG5405 ATP-dependent protease HslVU (ClpYQ) peptidase subunit COG5406 nucleosome binding factor SPN SPT16 subunit COG5407 preprotein translocase subunit Sec63 COG5410 hypothetical protein COG5412 phage-related protein COG5413 uncharacterized integral membrane protein COG5414 TATA-binding protein-associated factor Taf7 COG5416 uncharacterized integral membrane protein COG5417 uncharacterized ubiquitin-like protein YukD COG5418 predicted secreted protein COG5419 hypothetical protein COG5420 hypothetical protein COG5421 transposase COG5423 predicted metal-binding protein COG5424 pyrroloquinoline quinone (PQQ) biosynthesis protein C COG5425 uncharacterized protein Usg COG5426 uncharacterized membrane protein COG5427 uncharacterized membrane protein COG5428 uncharacterized protein YuzE COG5429 hypothetical protein COG5430 spore coat protein U-like protein COG5431 predicted nucleic acid-binding Zn finger protein COG5433 predicted transposase YbfD/YdcC COG5434 polygalacturonase COG5435 hypothetical protein COG5436 uncharacterized membrane protein COG5437 predicted secreted protein COG5438 uncharacterized membrane protein COG5439 hypothetical protein COG5440 hypothetical protein COG5441 uncharacterized protein (UPF0261 family) COG5442 flagellar biosynthesis regulator FlaF COG5443 flagellar biosynthesis regulator FlbT COG5444 predicted ribonuclease toxin of YeeF-YezG toxin-antitoxin module COG5445 uncharacterized protein YfaQ (DUF2300 family) COG5446 predicted cobalt transporter CbtA COG5447 hypothetical protein COG5448 hypothetical protein COG5449 hypothetical protein COG5450 Arc/MetJ family transcription regulator COG5451 predicted secreted protein COG5452 hypothetical protein COG5453 hypothetical protein COG5454 predicted secreted protein COG5455 Ni/Co efflux regulator RcnB COG5456 nitrogen fixation protein FixH COG5457 uncharacterized protein YjiS (DUF1127 family) COG5458 hypothetical protein COG5459 ribosomal protein RSM22 (predicted rRNA methylase) COG5460 uncharacterized protein (DUF2164 family) COG5461 type IV pilus biogenesis protein CpaD/CtpE COG5462 hypothetical protein COG5463 uncharacterized protein YgiB involved in biofilm formation COG5464 predicted transposase YdaD COG5465 hypothetical protein COG5466 predicted small metal-binding protein COG5467 hypothetical protein COG5468 hypothetical protein COG5469 predicted metal-binding protein COG5470 uncharacterized protein (DUF1330 family) COG5471 predicted RecA/RadA family phage recombinase COG5472 predicted small integral membrane protein COG5473 uncharacterized membrane protein COG5474 hypothetical protein COG5475 uncharacterized protein YodC (DUF2158 family) COG5476 microcystin degradation protein MlrC COG5477 predicted small integral membrane protein COG5478 low affinity Fe/Cu permease COG5479 uncharacterized protein with LGFP repeats COG5480 uncharacterized membrane protein COG5481 hypothetical protein COG5482 hypothetical protein COG5483 uncharacterized protein (DUF488 family) COG5484 uncharacterized protein YjcR COG5485 predicted ester cyclase COG5486 predicted metal-binding membrane protein COG5487 uncharacterized membrane protein YtjA (UPF0391 family) COG5488 uncharacterized membrane protein COG5489 uncharacterized protein (DUF736 family) COG5490 hypothetical protein COG5491 division protein CdvB (Snf7/Vps24/ESCRT-III family) COG5492 uncharacterized protein YjdB COG5493 hypothetical protein COG5494 predicted thioredoxin/glutaredoxin COG5495 predicted short-subunit dehydrogenase-like oxidoreductase (DUF2520 family) COG5496 predicted thioesterase COG5497 predicted secreted protein COG5498 endoglucanase Acf2 COG5499 antitoxin component HigA of HigAB toxin-antitoxin module COG5500 uncharacterized membrane protein COG5501 predicted secreted protein COG5502 uncharacterized protein (DUF2267 family) COG5503 DNA-dependent RNA polymerase auxiliary subunit epsilon COG5504 uncharacterized protein YjaZ COG5505 uncharacterized membrane protein COG5506 uncharacterized protein YueI COG5507 uncharacterized protein YbaA (DUF1428 family) COG5508 hypothetical protein COG5509 uncharacterized small protein (DUF1192 family) COG5510 predicted small secreted protein COG5511 capsid protein COG5512 predicted nucleic acid-binding Zn ribbon protein COG5513 predicted secreted protein COG5514 hypothetical protein COG5515 hypothetical protein COG5516 predicted RNA-binding Zn ribbon-like protein COG5517 3-phenylpropionate/cinnamic acid dioxygenase small subunit COG5518 capsid portal protein COG5519 uncharacterized protein (DUF927 family) COG5520 O-glycosyl hydrolase COG5521 maltodextrin utilization protein YvdJ COG5522 uncharacterized membrane protein YwaF COG5523 uncharacterized membrane protein COG5524 bacteriorhodopsin COG5525 phage terminase large subunit GpA-like protein COG5526 lysozyme family protein COG5527 plasmid replication initiation protein COG5528 uncharacterized membrane protein COG5529 pyocin large subunit-like protein COG5530 uncharacterized membrane protein COG5531 chromatin remodeling complex protein RSC6 COG5532 uncharacterized protein YfdQ (DUF2303 family) COG5533 ubiquitin C-terminal hydrolase COG5534 plasmid replication initiation protein COG5542 Gpi18-like mannosyltransferase COG5544 uncharacterized protein YfiM (DUF2279 family) COG5545 predicted P-loop ATPase COG5546 uncharacterized membrane protein COG5547 uncharacterized membrane protein COG5548 uncharacterized membrane protein (UPF0136 family) COG5549 predicted Zn-dependent protease COG5550 predicted aspartyl protease COG5551 CRISPR/Cas system endoribonuclease Cas6 (RAMP superfamily) COG5552 hypothetical protein COG5553 predicted metal-dependent enzyme (double-stranded beta helix superfamily) COG5554 nitrogen fixation protein COG5555 cytolysin (calcineurin-like family phosphatase) COG5556 hypothetical protein COG5557 Ni/Fe-hydrogenase subunit HybB-like protein COG5558 transposase COG5561 predicted metal-binding protein COG5562 uncharacterized protein YbcV (DUF1398 family) COG5563 uncharacterized membrane protein COG5564 predicted TIM-barrel enzyme COG5565 phage terminase large subunit-like protein COG5566 Mor family transcriptional regulator COG5567 predicted small lipoprotein YifL COG5568 hypothetical protein COG5569 Cu/Ag efflux protein CusF COG5570 hypothetical protein COG5571 uncharacterized protein YhjY with autotransporter beta-barrel domain COG5572 uncharacterized membrane protein COG5573 predicted nucleic acid-binding protein COG5577 spore coat protein CotF COG5578 uncharacterized membrane protein YesL COG5579 uncharacterized protein (DUF1810 family) COG5580 activator of HSP90 ATPase COG5581 c-di-GMP-binding flagellar brake protein YcgR COG5582 uncharacterized protein YpiB (UPF0302 family) COG5583 hypothetical protein COG5584 predicted small secreted protein COG5585 NAD+--asparagine ADP-ribosyltransferase COG5586 hypothetical protein COG5587 uncharacterized protein (DUF2461 family) COG5588 hypothetical protein COG5589 hypothetical protein COG5590 ubiquinone biosynthesis protein COQ9 COG5591 hypothetical protein COG5592 hemerythrin superfamily protein COG5595 predicted nucleic acid-binding Zn ribbon protein COG5597 alpha-N-acetylglucosamine transferase COG5598 trimethylamine:corrinoid methyltransferase-like protein COG5599 protein tyrosine phosphatase COG5602 histone deacetylase complex regulatory component SIN3 COG5605 cytochrome c oxidase subunit IV COG5606 predicted XRE-type DNA-binding protein COG5607 CHAD domain-containing protein COG5608 LEA14-like dessication related protein COG5609 uncharacterized protein YbcI COG5610 predicted HAD superfamily hydrolase COG5611 predicted nucleic-acid-binding protein COG5612 uncharacterized membrane protein COG5613 hypothetical protein COG5614 head-tail adaptor COG5615 uncharacterized membrane protein COG5616 TolB-like protein COG5617 uncharacterized membrane protein COG5618 predicted lipoprotein COG5619 hypothetical protein COG5620 hypothetical protein COG5621 predicted secreted hydrolase COG5622 protein required for attachment to host cells COG5624 transcription initiation factor TFIID subunit TAF12 COG5625 predicted DNA-binding transcriptional regulator COG5626 hypothetical protein COG5627 SUMO ligase MMS21 Smc5/6 complex component COG5628 predicted acetyltransferase COG5630 acetylglutamate synthase COG5631 predicted MarR family transcription regulator COG5632 N-acetylmuramoyl-L-alanine amidase CwlA COG5633 uncharacterized protein YcfL COG5634 uncharacterized protein YukJ COG5635 predicted NACHT family NTPase COG5637 uncharacterized membrane protein COG5639 hypothetical protein COG5640 secreted trypsin-like serine protease COG5642 uncharacterized protein (DUF2384 family) COG5643 formylmethanofuran dehydrogenase subunit E-like metal-binding protein COG5644 U3 small nucleolar RNA-associated protein 14 COG5645 uncharacterized protein YceK COG5646 uncharacterized protein YdhG (YjbR/CyaY superfamily) COG5649 hypothetical protein COG5650 uncharacterized membrane protein COG5651 PPE-repeat protein COG5652 VanZ family protein COG5653 CelD/BcsL family acetyltransferase involved in cellulose biosynthesis COG5654 RES domain-containing protein COG5655 plasmid rolling circle replication initiator protein Rep COG5658 uncharacterized membrane protein COG5659 SRSO17 transposase COG5660 predicted anti-sigma-YlaC factor YlaD COG5661 predicted secreted Zn-dependent protease COG5662 anti-sigma factor RsiW COG5663 uncharacterized HAD superfamily protein COG5664 predicted secreted Zn-dependent protease COG5665 CCR4-NOT transcriptional regulation complex NOT5 subunit