LOCUS NC_001829 4767 bp ss-DNA circular VRL 28-JAN-2010 DEFINITION Adeno-associated virus - 4, complete genome. ACCESSION NC_001829 VERSION NC_001829.1 DBSOURCE BioProject accession PRJNA14030 KEYWORDS RefSeq. SOURCE Adeno-associated virus - 4 ORGANISM Adeno-associated virus - 4 Viruses; ssDNA viruses; Parvoviridae; Parvovirinae; Dependoparvovirus. REFERENCE 1 (bases 1 to 4767) AUTHORS Chiorini,J.A., Yang,L., Liu,Y., Safer,B. and Kotin,R.M. TITLE Cloning of adeno-associated virus type 4 (AAV4) and generation of recombinant AAV4 particles JOURNAL J. Virol. 71 (9), 6823-6833 (1997) PUBMED 9261407 REFERENCE 2 (bases 1 to 4767) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (01-AUG-2000) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 3 (bases 1 to 4767) AUTHORS Chiorini,J.A., Yang,L., Kotin,R.M. and Safer,B. TITLE Direct Submission JOURNAL Submitted (17-FEB-1997) MHB, NHLBI,NIH, Bld 10/7D18 10 Center Dr. MSC1654, Bethesda, MD 20982-1654, USA COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence is identical to U89790. COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..4767 /mol_type="genomic DNA" /db_xref="taxon:57579" /isolate="ATCC VR-646" /organism="Adeno-associated virus - 4" gene 372..2243 /locus_tag="AAV4gp1" /db_xref="GeneID:1446390" CDS 372..2243 /locus_tag="AAV4gp1" /db_xref="GeneID:1446390" /codon_start=1 /protein_id="NP_044926.1" /translation="MPGFYEIVLKVPSDLDEHLPGISDSFVSWVAEKEWELPPDSDMD LNLIEQAPLTVAEKLQREFLVEWRRVSKAPEALFFVQFEKGDSYFHLHILVETVGVKS MVVGRYVSQIKEKLVTRIYRGVEPQLPNWFAVTKTRNGAGGGNKVVDDCYIPNYLLPK TQPELQWAWTNMDQYISACLNLAERKRLVAQHLTHVSQTQEQNKENQNPNSDAPVIRS KTSARYMELVGWLVDRGITSEKQWIQEDQASYISFNAASNSRSQIKAALDNASKIMSL TKTAPDYLVGQNPPEDISSNRIYRILEMNGYDPQYAASVFLGWAQKKFGKRNTIWLFG PATTGKTNIAEAIAHAVPFYGCVNWTNENFPFNDCVDKMVIWWEEGKMTAKVVESAKA ILGGSKVRVDQKCKSSAQIDPTPVIVTSNTNMCAVIDGNSTTFEHQQPLQDRMFKFEL TKRLEHDFGKVTKQEVKDFFRWASDHVTEVTHEFYVRKGGARKRPAPNDADISEPKRA CPSVAQPSTSDAEAPVDYADRYQNKCSRHVGMNLMLFPCRQCERMNQNVDICFTHGVM DCAECFPVSESQPVSVVRKRTYQKLCPIHHIMGRAPEVACSACELANVDLDDCDMEQ" /product="rep" gene 2260..4464 /locus_tag="AAV4gp2" /db_xref="GeneID:1446389" CDS 2260..4464 /locus_tag="AAV4gp2" /db_xref="GeneID:1446389" /codon_start=1 /protein_id="NP_044927.1" /translation="MTDGYLPDWLEDNLSEGVREWWALQPGAPKPKANQQHQDNARGL VLPGYKYLGPGNGLDKGEPVNAADAAALEHDKAYDQQLKAGDNPYLKYNHADAEFQQR LQGDTSFGGNLGRAVFQAKKRVLEPLGLVEQAGETAPGKKRPLIESPQQPDSSTGIGK KGKQPAKKKLVFEDETGAGDGPPEGSTSGAMSDDSEMRAAAGGAAVEGGQGADGVGNA SGDWHCDSTWSEGHVTTTSTRTWVLPTYNNHLYKRLGESLQSNTYNGFSTPWGYFDFN RFHCHFSPRDWQRLINNNWGMRPKAMRVKIFNIQVKEVTTSNGETTVANNLTSTVQIF ADSSYELPYVMDAGQEGSLPPFPNDVFMVPQYGYCGLVTGNTSQQQTDRNAFYCLEYF PSQMLRTGNNFEITYSFEKVPFHSMYAHSQSLDRLMNPLIDQYLWGLQSTTTGTTLNA GTATTNFTKLRPTNFSNFKKNWLPGPSIKQQGFSKTANQNYKIPATGSDSLIKYETHS TLDGRWSALTPGPPMATAGPADSKFSNSQLIFAGPKQNGNTATVPGTLIFTSEEELAA TNATDTDMWGNLPGGDQSNSNLPTVDRLTALGAVPGMVWQNRDIYYQGPIWAKIPHTD GHFHPSPLIGGFGLKHPPPQIFIKNTPVPANPATTFSSTPVNSFITQYSTGQVSVQID WEIQKERSKRWNPEVQFTSNYGQQNSLLWAPDAAGKYTEPRAIGTRYLTHHL" /product="capsid" ORIGIN 1 ttggccactc cctctatgcg cgctcgctca ctcactcggc cctggagacc aaaggtctcc 61 agactgccgg cctctggccg gcagggccga gtgagtgagc gagcgcgcat agagggagtg 121 gccaactcca tcatctaggt ttgcccactg acgtcaatgt gacgtcctag ggttagggag 181 gtccctgtat tagcagtcac gtgagtgtcg tatttcgcgg agcgtagcgg agcgcatacc 241 aagctgccac gtcacagcca cgtggtccgt ttgcgacagt ttgcgacacc atgtggtcag 301 gagggtatat aaccgcgagt gagccagcga ggagctccat tttgcccgcg aattttgaac 361 gagcagcagc catgccgggg ttctacgaga tcgtgctgaa ggtgcccagc gacctggacg 421 agcacctgcc cggcatttct gactcttttg tgagctgggt ggccgagaag gaatgggagc 481 tgccgccgga ttctgacatg gacttgaatc tgattgagca ggcacccctg accgtggccg 541 aaaagctgca acgcgagttc ctggtcgagt ggcgccgcgt gagtaaggcc ccggaggccc 601 tcttctttgt ccagttcgag aagggggaca gctacttcca cctgcacatc ctggtggaga 661 ccgtgggcgt caaatccatg gtggtgggcc gctacgtgag ccagattaaa gagaagctgg 721 tgacccgcat ctaccgcggg gtcgagccgc agcttccgaa ctggttcgcg gtgaccaaga 781 cgcgtaatgg cgccggaggc gggaacaagg tggtggacga ctgctacatc cccaactacc 841 tgctccccaa gacccagccc gagctccagt gggcgtggac taacatggac cagtatataa 901 gcgcctgttt gaatctcgcg gagcgtaaac ggctggtggc gcagcatctg acgcacgtgt 961 cgcagacgca ggagcagaac aaggaaaacc agaaccccaa ttctgacgcg ccggtcatca 1021 ggtcaaaaac ctccgccagg tacatggagc tggtcgggtg gctggtggac cgcgggatca 1081 cgtcagaaaa gcaatggatc caggaggacc aggcgtccta catctccttc aacgccgcct 1141 ccaactcgcg gtcacaaatc aaggccgcgc tggacaatgc ctccaaaatc atgagcctga 1201 caaagacggc tccggactac ctggtgggcc agaacccgcc ggaggacatt tccagcaacc 1261 gcatctaccg aatcctcgag atgaacgggt acgatccgca gtacgcggcc tccgtcttcc 1321 tgggctgggc gcaaaagaag ttcgggaaga ggaacaccat ctggctcttt gggccggcca 1381 cgacgggtaa aaccaacatc gcggaagcca tcgcccacgc cgtgcccttc tacggctgcg 1441 tgaactggac caatgagaac tttccgttca acgattgcgt cgacaagatg gtgatctggt 1501 gggaggaggg caagatgacg gccaaggtcg tagagagcgc caaggccatc ctgggcggaa 1561 gcaaggtgcg cgtggaccaa aagtgcaagt catcggccca gatcgaccca actcccgtga 1621 tcgtcacctc caacaccaac atgtgcgcgg tcatcgacgg aaactcgacc accttcgagc 1681 accaacaacc actccaggac cggatgttca agttcgagct caccaagcgc ctggagcacg 1741 actttggcaa ggtcaccaag caggaagtca aagacttttt ccggtgggcg tcagatcacg 1801 tgaccgaggt gactcacgag ttttacgtca gaaagggtgg agctagaaag aggcccgccc 1861 ccaatgacgc agatataagt gagcccaagc gggcctgtcc gtcagttgcg cagccatcga 1921 cgtcagacgc ggaagctccg gtggactacg cggacaggta ccaaaacaaa tgttctcgtc 1981 acgtgggtat gaatctgatg ctttttccct gccggcaatg cgagagaatg aatcagaatg 2041 tggacatttg cttcacgcac ggggtcatgg actgtgccga gtgcttcccc gtgtcagaat 2101 ctcaacccgt gtctgtcgtc agaaagcgga cgtatcagaa actgtgtccg attcatcaca 2161 tcatggggag ggcgcccgag gtggcctgct cggcctgcga actggccaat gtggacttgg 2221 atgactgtga catggaacaa taaatgactc aaaccagata tgactgacgg ttaccttcca 2281 gattggctag aggacaacct ctctgaaggc gttcgagagt ggtgggcgct gcaacctgga 2341 gcccctaaac ccaaggcaaa tcaacaacat caggacaacg ctcggggtct tgtgcttccg 2401 ggttacaaat acctcggacc cggcaacgga ctcgacaagg gggaacccgt caacgcagcg 2461 gacgcggcag ccctcgagca cgacaaggcc tacgaccagc agctcaaggc cggtgacaac 2521 ccctacctca agtacaacca cgccgacgcg gagttccagc agcggcttca gggcgacaca 2581 tcgtttgggg gcaacctcgg cagagcagtc ttccaggcca aaaagagggt tcttgaacct 2641 cttggtctgg ttgagcaagc gggtgagacg gctcctggaa agaagagacc gttgattgaa 2701 tccccccagc agcccgactc ctccacgggt atcggcaaaa aaggcaagca gccggctaaa 2761 aagaagctcg ttttcgaaga cgaaactgga gcaggcgacg gaccccctga gggatcaact 2821 tccggagcca tgtctgatga cagtgagatg cgtgcagcag ctggcggagc tgcagtcgag 2881 ggcggacaag gtgccgatgg agtgggtaat gcctcgggtg attggcattg cgattccacc 2941 tggtctgagg gccacgtcac gaccaccagc accagaacct gggtcttgcc cacctacaac 3001 aaccacctct acaagcgact cggagagagc ctgcagtcca acacctacaa cggattctcc 3061 accccctggg gatactttga cttcaaccgc ttccactgcc acttctcacc acgtgactgg 3121 cagcgactca tcaacaacaa ctggggcatg cgacccaaag ccatgcgggt caaaatcttc 3181 aacatccagg tcaaggaggt cacgacgtcg aacggcgaga caacggtggc taataacctt 3241 accagcacgg ttcagatctt tgcggactcg tcgtacgaac tgccgtacgt gatggatgcg 3301 ggtcaagagg gcagcctgcc tccttttccc aacgacgtct ttatggtgcc ccagtacggc 3361 tactgtggac tggtgaccgg caacacttcg cagcaacaga ctgacagaaa tgccttctac 3421 tgcctggagt actttccttc gcagatgctg cggactggca acaactttga aattacgtac 3481 agttttgaga aggtgccttt ccactcgatg tacgcgcaca gccagagcct ggaccggctg 3541 atgaaccctc tcatcgacca gtacctgtgg ggactgcaat cgaccaccac cggaaccacc 3601 ctgaatgccg ggactgccac caccaacttt accaagctgc ggcctaccaa cttttccaac 3661 tttaaaaaga actggctgcc cgggccttca atcaagcagc agggcttctc aaagactgcc 3721 aatcaaaact acaagatccc tgccaccggg tcagacagtc tcatcaaata cgagacgcac 3781 agcactctgg acggaagatg gagtgccctg acccccggac ctccaatggc cacggctgga 3841 cctgcggaca gcaagttcag caacagccag ctcatctttg cggggcctaa acagaacggc 3901 aacacggcca ccgtacccgg gactctgatc ttcacctctg aggaggagct ggcagccacc 3961 aacgccaccg atacggacat gtggggcaac ctacctggcg gtgaccagag caacagcaac 4021 ctgccgaccg tggacagact gacagccttg ggagccgtgc ctggaatggt ctggcaaaac 4081 agagacattt actaccaggg tcccatttgg gccaagattc ctcataccga tggacacttt 4141 cacccctcac cgctgattgg tgggtttggg ctgaaacacc cgcctcctca aatttttatc 4201 aagaacaccc cggtacctgc gaatcctgca acgaccttca gctctactcc ggtaaactcc 4261 ttcattactc agtacagcac tggccaggtg tcggtgcaga ttgactggga gatccagaag 4321 gagcggtcca aacgctggaa ccccgaggtc cagtttacct ccaactacgg acagcaaaac 4381 tctctgttgt gggctcccga tgcggctggg aaatacactg agcctagggc tatcggtacc 4441 cgctacctca cccaccacct gtaataacct gttaatcaat aaaccggttt attcgtttca 4501 gttgaacttt ggtctccgtg tccttcttat cttatctcgt ttccatggct actgcgtaca 4561 taagcagcgg cctgcggcgc ttgcgcttcg cggtttacaa ctgccggtta atcagtaact 4621 tctggcaaac cagatgatgg agttggccac attagctatg cgcgctcgct cactcactcg 4681 gccctggaga ccaaaggtct ccagactgcc ggcctctggc cggcagggcc gagtgagtga 4741 gcgagcgcgc atagagggag tggccaa //