LOCUS NC_022519 5722 bp DNA circular VRL 27-NOV-2013 DEFINITION African elephant polyomavirus 1, complete genome. ACCESSION NC_022519 VERSION NC_022519.1 DBSOURCE BioProject accession PRJNA222309 KEYWORDS RefSeq. SOURCE African elephant polyomavirus 1 ORGANISM African elephant polyomavirus 1 Viruses; dsDNA viruses, no RNA stage; Polyomaviridae; unclassified Polyomaviridae. REFERENCE 1 (bases 1 to 5722) AUTHORS Stevens,H., Bertelsen,M.F., Sijmons,S., Van Ranst,M. and Maes,P. TITLE Characterization of a Novel Polyomavirus Isolated from a Fibroma on the Trunk of an African Elephant (Loxodonta africana) JOURNAL PLoS ONE 8 (10), E77884 (2013) PUBMED 24205012 REMARK Publication Status: Online-Only REFERENCE 2 (bases 1 to 5722) CONSRTM NCBI Genome Project TITLE Direct Submission JOURNAL Submitted (30-SEP-2013) National Center for Biotechnology Information, NIH, Bethesda, MD 20894, USA REFERENCE 3 (bases 1 to 5722) AUTHORS Maes,P., Stevens,H., Bertelsen,M.F., Sijmons,S. and Van Ranst,M. TITLE Direct Submission JOURNAL Submitted (24-MAY-2013) Microbiology and Immunology, Clinical Virology - Rega Institute, Minderbroedersstraat 10, Leuven BE3000, Belgium COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence is identical to KF147833. ##Assembly-Data-START## Assembly Method :: CLC Genomics Workbench v. 5.5.1 Sequencing Technology :: Sanger dideoxy sequencing; 454 ##Assembly-Data-END## COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..5722 /mol_type="genomic DNA" /country="Denmark" /isolation_source="protruding ulcerated fibroma on trunk" /collection_date="2011" /host="Loxodonta africana" /db_xref="taxon:1399914" /isolate="DK-1/2011" /organism="African elephant polyomavirus 1" gene 623..1615 /locus_tag="AelPyV_gp2" /db_xref="GeneID:17099701" CDS 623..1615 /locus_tag="AelPyV_gp2" /db_xref="GeneID:17099701" /codon_start=1 /protein_id="YP_008603283.1" /translation="MGAVLALLSDVVELAAASGFTAEALVSGEFISALEALEAEINSI VLFEEASQLEALTSLGISADTFGVLTSIPINLAEQLATVAALQHSSLAVIALVTATLN LTWSHSIPDMALQLWFPPVDYLFPGVTQFSRFLRYIDPTQWGPELFHHLTQAFFSTFR DATRRQLTDASRNIAERTAKTLVETLVDLLTNATWAIAHLPSDVYTFLDNYYEELPPL NPAQFSGIRKRLGKVNPYEQQDVFANTVSAEFVTKVTAPGGAMQKHAPDWVLPLLLGL FDEDYRQVTPRDGPAAKRRRTTLRTIQKTPPKTGKRPPNTRARRSASSRSKKRA" /product="minor capsid VP2 protein" gene 956..1615 /locus_tag="AelPyV_gp3" /db_xref="GeneID:17099697" CDS 956..1615 /locus_tag="AelPyV_gp3" /db_xref="GeneID:17099697" /codon_start=1 /protein_id="YP_008603284.1" /translation="MALQLWFPPVDYLFPGVTQFSRFLRYIDPTQWGPELFHHLTQAF FSTFRDATRRQLTDASRNIAERTAKTLVETLVDLLTNATWAIAHLPSDVYTFLDNYYE ELPPLNPAQFSGIRKRLGKVNPYEQQDVFANTVSAEFVTKVTAPGGAMQKHAPDWVLP LLLGLFDEDYRQVTPRDGPAAKRRRTTLRTIQKTPPKTGKRPPNTRARRSASSRSKKR A" /product="minor capsid VP3 protein" gene 1485..2603 /locus_tag="AelPyV_gp1" /db_xref="GeneID:17099698" CDS 1485..2603 /locus_tag="AelPyV_gp1" /db_xref="GeneID:17099698" /codon_start=1 /protein_id="YP_008603285.1" /translation="MAPQRKGGGRPCVPSKRPLRKPENVPRILVRGGVQVLEVRSGPD SIVDIECFLQPRMGEPEGDDYYGYSELITVGTEKSTDTPPFKQLPCYSAAQVQLPNLN PDLTCETLLMWEAVSTKTEVLGISSLVNVHSQSKRVEPEGIGYPIAGINYHFFAVGGQ PLDLQALVSNFSATYPAERKVPVKDQLHPIAQVLDPNLKTTLDEDGTYPIEVWGADPS KNDNTRYFGTLTGGAQTPPVLSVTNTTTTILLDEYGVGPLCKGGRLYLAAADICGFST ESTGKMRYRGLPRFFKVKLRKRAVKNPYAIGSLLNSFFSSFLPQVKGQPMTGDKGQVE EVTIFQGTEPLPADPDLIRSVDQFGQFLTKEPAQANVV" /product="major capsid protein VP1" /note="72 pentamers of VP1 comprise the outer capsid and form a T = 7 icosahedral lattice; VP1 contains an amino-terminal bipartite nuclear targeting signal that overlaps its DNA-binding-domain; facilitates binding of genomic DNA and entry into target cells" gene complement(3458..5722) /locus_tag="AelPyV_gp4" /db_xref="GeneID:17099699" CDS complement(join(3458..5185,5474..5722)) /locus_tag="AelPyV_gp4" /db_xref="GeneID:17099699" /codon_start=1 /protein_id="YP_008603286.1" /translation="MDRALNREDSKSLMGLLGLNMEQYGNVPLMYNRYKKKCLQYHPE KGGNATIMKELNRLWTQFTCSLEKVRRQDEEGQSWSRSEVPTYGTPEWEAWWSDFNRD YDDGSSSAAEDETDNAQFNTNFRPTFSTPPKKKTEAPSDFPQCLDEYLSKALFSNKTV QCFLIYTTKDKAMRLYHILMEKFNPTFLSRHSFEFNSMLFLLTPKKHRVTAIYNFCAK HCVVSFLKVKAPLNPFLCYGRLCKAPFCMQQESVPGGLRDNYYAPDEQEGSKQVCWKT IAKYASDIECTDVYLLLGFYTEFEEDPDLCTKCDHHTTPMHFLHHRQHHSNAKLFAES KNQKSVCTQAVDRVIGQLRVKMTLTSRRDLLTGRFQKLLKDMEFMFGAYGSADLKLYM CGVAWYSCFFLNFHNFIAGFLKCMVDNIPKHRYYLFKGPIDSGKTTLASALLDLCGGR SLNVNGPFDRLTFELGCAMDQFMVCLDDVKGSMPEDKRLPTGQGVANLDHLRDHMDGC VDVNLEKKHSNKKPQKFPPGVVTMNNYTLPMTLTARFCSIVQFKPKAYLRNSLKNTDD LLRHRVLNSGITLFLLLIYFCDVNDFVSDLHEDIRGWKQRMDSTVSPTAFMQMKRNVG MGTCILEDEMNNETQDSGLESGLETETDSRDFTD" /product="large T antigen" /note="binds to the viral origin of replication; regulates the transcription of early region mRNA; helicase activity facilitates movement of the virion DNA replication fork; small T antigen shares a region in common with the large T antigen known as the J-domain; J-domain is required for multiple processes including assembly, viral genomic DNA replication and transcription" gene 5207..5722 /locus_tag="AelPyV_gp5" /db_xref="GeneID:17099700" CDS complement(5207..5722) /locus_tag="AelPyV_gp4" /db_xref="GeneID:17099699" /codon_start=1 /protein_id="YP_008603287.1" /translation="MDRALNREDSKSLMGLLGLNMEQYGNVPLMYNRYKKKCLQYHPE KGGNATIMKELNRLWTQFTCSLEKVRRQDEEGQSWSRSEVSARPHPDNLFGRFPDCFL GRSPKCSCYLCILALSHSIRKGTVRGPNVWMKCCCFTCFCIWFGLHPDYNACKAWAEV IKRTPIKHLNI" /product="small T antigen" /note="promotes the efficient replication of genomic DNA; binds to and negativley regulates the function of protein phosphotase (PP2A) thereby accelerating the progression to S-phase; shares a region in common with the large T-antigen known as the J-domain; J-domain is required for multiple processes including assembly, viral genomic DNA replication and transcription" ORIGIN 1 tttgcctctg aagaagcctc tgaaaagcct ctcattactt taagaattag aaggaggctt 61 aagcctcagg cctccttata tttttcaata aaaaaggaca gtaatttgta ccacatgcgg 121 aacggatgca gggtcacata aagtaatggt tgggctttac aaattacatc gttctattac 181 cgcaggtttg gctgtcaatt taacttggcg gcgggcaaaa cttggcagaa catactggcg 241 tctttgcaga aacattttaa cacttttttt gatttagtac tgatgctttt ttaatatttt 301 tcagaacttt ggtagagatg tgtgcaaaac gtttgcttgg aagtttttac ccacgggaaa 361 taggttcatg gaaggacact aagaggcatg tcactgccaa aaattccgaa ccgaacctca 421 tgacataagt aattgcttca gtctgtgcgg gggttggggc aactgcatat ataccgctaa 481 atctcctcag ttctttgtta gcacattaac cagtgcctgg acaggatgca caactgtaag 541 tatgatttac cttttgctat ttttaagggg tttgaaccgt tggaattggc gggaatgagt 601 aagtatgttt ctgttttagg agatgggcgc cgtgttggca ttactgtcag atgttgttga 661 gcttgcggca gcatctggtt ttactgctga agcactcgtg tcaggagaat tcatctcagc 721 tttggaagca ttagaggctg aaattaactc tatagttctc tttgaagagg catctcagct 781 agaggcgttg acctcgctgg gcatatcagc ggatactttt ggcgttttaa catctatacc 841 tataaactta gctgaacagc ttgctacggt agctgcttta cagcactcat ctttagctgt 901 aattgccctt gtcacagcta ctttaaatct tacctggagt cactctatac ctgatatggc 961 ccttcaactt tggtttcctc cagttgatta cctattccct ggtgtaacgc aatttagcag 1021 gtttttaaga tatattgatc caacccagtg gggccctgaa ttgttccatc acctgacaca 1081 agcttttttt tccaccttcc gcgatgctac acgtagacaa ttaaccgatg catcccggaa 1141 tatagccgaa agaacagcca agacattggt tgaaacacta gttgatttgc taacaaatgc 1201 tacgtgggca atagcccact tgccgtctga cgtctataca tttttagata attactatga 1261 ggaactgccg cccctcaatc cagctcagtt tagtggtatt cggaaacgct tgggaaaggt 1321 taacccttat gaacaacagg atgtgtttgc taacactgta tctgcagagt ttgtgaccaa 1381 ggttactgca cctggtggtg caatgcaaaa acatgctcct gactgggtcc ttcctttgct 1441 attaggattg tttgatgaag attatagaca ggtaacacct agagatggcc ccgcagcgaa 1501 aaggaggcgg acgaccctgc gtaccatcca aaagacccct ccgaaaaccg gaaaacgtcc 1561 cccgaatact cgtgcgcgga ggagtgcaag ttctagaagt aagaagcggg cctgattcta 1621 ttgttgacat agaatgcttt ttgcagccac gtatggggga acctgagggg gatgattatt 1681 atgggtatag cgagttgatt actgttggaa cagagaaaag cactgacaca cctcccttta 1741 aacagttacc atgctatagt gcagcacagg ttcagcttcc taatcttaac cctgatctga 1801 cctgtgaaac cttgctaatg tgggaagctg tgtcaaccaa aacagaagtt cttggaatct 1861 cttcacttgt caatgtacat tctcaatcaa aaagagtgga accagaaggc atcgggtatc 1921 ccatagctgg cattaattat catttttttg ctgtgggagg tcaacccttg gatctgcagg 1981 cacttgtaag taatttcagt gcaacctatc ctgcagaaag gaaagttcct gtgaaggacc 2041 agctgcaccc aattgcacaa gtattggatc caaatttgaa aaccacatta gacgaagatg 2101 ggacctatcc catcgaggtc tggggtgcag atccttctaa gaatgacaac acaagatatt 2161 ttggaacact cacaggtggt gcacagacgc caccggttct ctcggttact aacacaacaa 2221 caacaattct cctggatgaa tacggggtgg ggccactctg caagggaggg aggctttatt 2281 tggctgctgc agatatttgt gggttttcaa cggaaagtac aggtaaaatg aggtatcggg 2341 gtttgcctag gttttttaag gtcaaactta ggaaaagggc tgtgaaaaat ccttatgcta 2401 taggttcttt actgaattct ttcttttcca gtttcttgcc acaagtcaaa gggcagccga 2461 tgacaggtga caagggacag gtggaagagg tcaccatctt ccagggaacc gaaccactcc 2521 ctgcggatcc ggaccttata agatctgtgg accaatttgg ccaatttctt actaaggagc 2581 ctgcgcaggc caatgttgtt taagtttact aagatggtcg tgctaaccca tggcattctg 2641 cttggcactg ttaccctcat gtcatcaggg actaaagtat acaacttgga accctcataa 2701 catctgggac ttacaatacc ttacttaaca acccaatacc atcggggact caaccctaac 2761 tatctgggaa tttctgagga actttatact ctttctttct tcttctttgc gcccatcttc 2821 tgcatactga gtgaggaaat ttatcttctg aggatttgaa ctttgttact cttaaatgga 2881 caatttctga ggttttggac tactgtgaag cgctacaggt aataagctgc tacgatagga 2941 atgagtttat ggacatacgt gtactgtacc attaatttat gaagataatt tattgcagaa 3001 gagtatttat tatatatttt tttactgaaa ctagaaacaa acaagactca ccatcgacaa 3061 ggttgcaaat gttttttttc ttttaaaaag taccaatcca ttgagacaat tcttccctcc 3121 aatggttttt ttttgcctga aataacatct tgtacaacta taacatctga ttatgccaca 3181 aggacttcca cttatttcca taggttttgt tctttccttt ttctaccaac ttaccatcac 3241 gagtttccca catgtcaagg acttttacat tgtgctagac ccgtatcgtc atcaggataa 3301 accgagcaat cagttttgtg aacaaagtac atcttggact attattgtgt tgttgccttt 3361 tattgttttg tgttttgtgc aaatgcaaga gctcacatag caagcagtga ggtgtaaata 3421 ttcgttaaaa tccaataaac cccctcccct taacctctta gtctgtgaag tctcttgaat 3481 ccgtttccgt ttcaaggcca gattcaaggc ctgaatcttg cgtttcattg ttcatctcat 3541 cctccaaaat acatgttccc attccaacat tgcgcttcat ttgcataaac gcagtgggag 3601 acacagtgct gtccatacgt tgcttccatc cacgtatatc ctcgtgcagg tcggaaacaa 3661 aatcatttac atcacagaaa tatatcagta aaaggaacaa tgtaatgcca ctattaagca 3721 ctctgtgtct gagcaagtcg tctgtattct taagtgaatt gcgcaggtac gctttgggct 3781 taaactgcac aatgctgcag aatctggcag tgagagtcat gggtaatgta tagttgttca 3841 tggttacaac ccctggaggg aatttctggg gctttttatt ggaatgtttt ttttctaagt 3901 tcacatctac acagccatcc atgtggtctc ggagatgatc aaggttagca acaccttgtc 3961 ctgtgggcaa tctcttatcc tctggcattg accccttgac atcatctaag cataccataa 4021 actggtccat ggcacatcca agttcaaatg tcagccggtc aaagggtcca tttacattta 4081 gagacctccc cccacacaga tctaataatg cacttgcaag tgttgtctta cctgagtcaa 4141 ttgggccctt gaacaggtaa tatctatgct ttggtatgtt atctaccata catttcaaaa 4201 acccagctat gaagttgtga aagttaagaa aaaagcatga gtaccacgcc accccacaca 4261 tatatagctt taaatcggca gaaccataag caccaaacat gaattccatg tctttaagga 4321 gcttctgaaa tcgccctgtt aataggtctc ttctgctcgt tagggtcatt tttactctga 4381 gctggcctat aactcgatcc acagcctgtg tgcatacaga tttctgattt ttgctttcgg 4441 caaaaagttt agcattagaa tggtgctgtc tgtgatgcaa gaagtgcata ggtgtggtat 4501 gatgatcaca tttggtacat aagtctgggt cctcctcaaa ctcagtatag aatcccagca 4561 acaagtagac atctgtacat tcaatatcgc ttgcatattt agctattgtt ttccaacata 4621 cttgcttcga accctcctgc tcatcaggag cataataatt atctctcagg ccccccggca 4681 cactttcctg ctgcatgcaa aaaggggctt tacataagcg tccataacat aaaaaagggt 4741 taaggggggc tttgaccttt agaaagctaa ccacacaatg cttagcacag aaattataaa 4801 tggcagtgac tctgtgtttt tttggcgtta gtaagaacag catgctattg aactcaaagg 4861 aatgtctgct caaaaaggtg gggttaaatt tctccatcaa tatgtgatac agccgcattg 4921 ctttgtcctt agtagtgtat atcagaaagc attggacagt tttgttggag aaaagagctt 4981 tgctaagata ctcatccaag cactgcggaa aatcagatgg ggcctcagtt tttttcttcg 5041 gtggggtact gaaggtgggt ctaaagttcg tgttgaactg ggcattatca gtctcatctt 5101 ctgctgcaga ggaagaaccg tcatcatagt cacgattaaa atcgctccac catgcctccc 5161 actcaggggt cccgtaagtt ggcacctaaa agacagtgag ctcaccttag atgttcaggt 5221 gcttaatagg tgttcttttg atcacttcgg cccaggcttt gcaggcatta tagtccggat 5281 gtaatccaaa ccaaatgcaa aagcatgtaa agcaacaaca tttcatccat acattaggtc 5341 cacggacagt ccccttcctg atgctgtggc ttaatgccaa tatgcacagg tagcagctac 5401 atttgggaga gcgacctagg aagcaatcag gaaaccttcc aaacaaatta tctggatgag 5461 gacgtgcact aacctcagag cggctccagc tttgtccctc ctcatcctgt ctccgcactt 5521 tttctaggct gcaggtgaat tgagtccata acctattcaa ctccttcatg atggttgcgt 5581 tgccaccttt ctctggatga tactgcaggc attttttttt atacctgtta tacataagag 5641 gaacattgcc gtactgttcc atattgagac ctaaaagccc cataagtgac ttactgtctt 5701 ctctattcaa agccctgtcc at //