LOCUS KU159177 8415 bp DNA linear VRL 30-MAR-2016 DEFINITION Avian leukosis and sarcoam virus SJ-5 strain, complete genome. ACCESSION KU159177 VERSION KU159177.1 KEYWORDS acutely transforming virus; ALV-J associated; defective virus; v-src oncogene. SOURCE Avian leukosis and sarcoma virus ORGANISM Avian leukosis and sarcoma virus Viruses; Retro-transcribing viruses; Retroviridae; Orthoretrovirinae; Alpharetrovirus. REFERENCE 1 (bases 1 to 8415) AUTHORS Wang,Y., Li,J., Li,Y., Fang,L., Sun,X., Chang,S., Zhao,P. and Cui,Z. TITLE Identification of Avian leukosis virus subgroup J associated acutely transforming viruses carrying the v-src oncogene in layer chickens JOURNAL J. Gen. Virol. (2016) In press PUBMED 26842006 REMARK Publication Status: Available-Online prior to print REFERENCE 2 (bases 1 to 8415) AUTHORS Wang,Y., Li,J., Zhao,P., Chang,S. and Cui,Z. TITLE Direct Submission JOURNAL Submitted (15-NOV-2015) College of Animal Science and Veterinary Medicine, Shandong Agricultural University, Daizong Street 61, Tai'an City, Shandong Province 271018, China FEATURES Location/Qualifiers source 1..8415 /mol_type="genomic DNA" /country="China" /collection_date="01-Jun-2010" /host="Gallus gallus (chicken)" /note="associated defective virus; subgroup: J" /db_xref="taxon:1806567" /isolate="SJ-5" /organism="Avian leukosis and sarcoma virus" repeat_region 1..325 /rpt_type=long_terminal_repeat /note="5' LTR" gene 622..2727 /gene="gag" CDS 622..2727 /codon_start=1 /protein_id="AMP18897.1" /gene="gag" /translation="MEAVIKVISSACKTYCGKTSPSKKEIGAMLSLLQKEGLLMSLSD LYSPGSWDPITAALTQRAMVLGKSGELKTWGLVLGALKAAREEQVTSEQAKFWLGLGG GRVSPPGPECIEKPATERRIDKGEEVGETTVQRDAKMAPEETATPKTVGTSCYHCGTA IGCNCATASAPPPPYVGSGLYPSLAGVGEQQGQGGDTPRGAEQPRAEPGHAGQAPGPA LTDWARIREELASTGPPVVAMPVVIKTEGPAWTPLEPKLITRLADTVRTKGLRSPITM AEVEALMSSPLLPHDVTNLMRVILGPAPYALWMDAWGVQLQTVIAAATRDPRHPANGQ GRGERTNLDRLKGLADGMAGNPEGHAALLRPGELVAITASALQAFREVARLAEPTDPW AEITQGPSESFVDFANRLIKAVEGSDLPPSARAPVIIDCFRQKSQPDIQQLIRAAPST LTTPGEIIKYVLDRQKTAPLTDRGIAAAMSSAIQPLVMAVVNRERDGQTGSGGRARGL CYTCGSPGHYQAQCPKKRKSGNSRERCQLCDGMGHNAKQCRRRDGNQGQRPGRGLSSG PWPVSQRPAVSLAMTMEHKDRPLVRVILTNTGSHPVKQRSVYITALLDSGADITIISE EDWPTDWPVMEAANPQIHGIGGGIPMRKSRDMIEVGVINRDGSLERPLLLFPAVAMVR GSILGRDCLQGLGLRLTNL" /product="gag protein" gene <2745..5366 /gene="pol" CDS <2745..5366 /codon_start=1 /protein_id="AMP18898.1" /gene="pol" /translation="TVALHLAIPLKWKPDHTPVWIDQWPLPEGKLVALTQLVEKELQL GHIEPSLSCWNTPVFVIRKASGSYRLLHDLRAVNAKLVPFGAVQQGAPVLSALPRGWP LMVLDLKDCFFSIPLAEQDREAFAFTLPSVNNQAPARRFQWKVLPQGMTCSPTICQLV VGQVLEPLRLKHPSLRMLHYMDDLLLAASSHDGLEAAGEEVISTLERAGFTISPDKIQ REPGVQYLGYKLGSTYVAPVGLVAEPRIATLWDVQKLVGSLQWLRPALGIPPRLMGPF YEQLRGSDPNEAREWNLDMKMAWREIVQLSTTAALERWDPALPLEGAVARCEQGAIGV LGQGLSTHPRPCLWLFSTQPTKAFTAWLEVLTLLITKLRASAVRTFGKEVDVLLLPAC FREDLPLPEGILLALRGFAGKIRSSDTPSIFDIARPLHVSLKVRVTDHPVPGPTVFTD ASSSTHKGVVVWREGPRWEIKEIADLGASVQQLEARAVAMALLLWPTTPTNVVTDSAF VAKMLLKMGQEGVPSTAAAFILEDALSQRSAMAAVLHVRSHSEVPGFFTEGNDVADSQ ATFQAYPLREAKDLHTALHIGPRALSKACNISMQQAREVVQTCPHCNSAPALEAGVNP RGLGPLQIWQTDFTLEPRMAPRSWLAVTVATASSAIVVTQHGRVTSVAARHHWATAIA VLGRPKAIKTDNGSCFTSKSTREWLARWGIAHTTGIPGNSQGQAMVERANRLLKDKIR VLAEGDGFMKRIPTGKQGELLAKAMYALNHFERGENTKTPIQKHWRPTVLTEGPPVKI RIETGEWEKGWNVLVWGRGYAAVKNRDTDKIIWVPSRKVKPDITQKDELTKKDEASPL FAGISDWAPWKGEQEGL" /product="pol protein" misc_feature 5366..7771 /note="nonfunctional env protein due to mutation" gene 5879..7231 /gene="v-src" CDS 5879..7231 /codon_start=1 /protein_id="AMP18899.1" /gene="v-src" /translation="MALAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTEGDWWL AHSLTTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNPENPRGTFLVRESE TTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFSSLQQLVAYYSKHADG LCHRLTNVCPTSKPQTQGLAKDAWEIPRESLRLGVKLGQGCFGEVWMGTWNGTTRVAI KTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKG EMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARL IEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVN REVLDQVERGYRMPCPPECPESLHDLMCQCWRKDPEERPTFEYLQAFLEDYFTSTEPQ " /product="truncated v-src protein" /note="contains N-terminal deletion" repeat_region 8091..8415 /rpt_type=long_terminal_repeat /note="3' LTR" ORIGIN 1 tgtagtctta tgcaatactc ttatgtaacg atgaaacagc aatatgcctt ataaggagaa 61 agaaggcact gtacacgttg attggtggaa gtaaggtggt atggtcatgg tgtgatcgtg 121 ccttattagg aagacaacag acgggtcaga catggattgg acgatcccct tagttccgcg 181 ttgcagagag attgtattta agtgcctagc ttgatacaat aaacgccatt ttacctccca 241 ccacattggt gtgcacctgg gtagatggac agaccgttga gtccctaacg attgcgaaca 301 cctgaatgaa gctgaaggct tcatttggtg accccgacgt gatcgttagg gaatagtggt 361 cggccacagg cggcgtggcg atcctgccct catccgtctc gcttaacgga gcgaggacga 421 tgaccctagt agagggggct gcggcttagg agggcagaag ctgagtgacg tcggagggag 481 ctccacggcc gggggccaag ataacctacc gagaactcag agagtcgttg gaagacggga 541 aggaagcccg acgactgagc agtccacccc aggcgcgatt ccggttgctc tgcgtgactc 601 tggtcgcccg gtggatcaag catggaagcc gtcataaagg tgatttcgtc cgcgtgtaaa 661 acctattgcg ggaaaacctc tccttctaag aaggaaatag gggccatgtt gtccctgtta 721 caaaaggaag ggttgcttat gtccctctca gacttatatt ccccggggtc ctgggatccc 781 attaccgcgg cactcaccca gcgggcaatg gtacttggga aatcgggaga gttaaaaacc 841 tggggattgg ttttgggggc attgaaggcg gctcgagagg aacaggttac atctgagcaa 901 gcaaagtttt ggttgggatt agggggaggg agggtctctc ccccaggtcc ggagtgcatc 961 gagaaaccag caacggagcg gcgaatcgac aagggggagg aagtgggaga aacaactgtg 1021 cagcgagatg cgaagatggc gccggaggaa acggccacac ctaaaaccgt tggcacatcc 1081 tgctatcatt gcggaacagc tattggctgt aattgcgcca cagcctcggc ccctcctcct 1141 ccttatgtgg ggagtggttt gtatccttcc ctggcggggg tgggagagca gcagggccag 1201 gggggtgaca cacctcgggg ggcggaacag ccaagggcgg agccagggca cgcgggtcag 1261 gcccctgggc cggccctgac tgactgggca aggatcaggg aggagcttgc gagtacaggt 1321 ccgcccgtgg tggccatgcc tgtagtgatt aagacagagg gacccgcctg gacccctctg 1381 gagccaaaat tgatcacaag actggctgat acggtcagga ccaagggctt acgatccccg 1441 atcactatgg cagaagtgga agcgcttatg tcctccccgc tgctgccgca tgacgtcacg 1501 aatctaatga gagttatttt aggacctgcc ccatatgcct tatggatgga cgcttgggga 1561 gtccaactac agacggttat agcggcagcc actcgcgacc cccgacaccc agcgaacggt 1621 caagggcggg gggaacggac taacttggat cgtttaaagg gtttggcgga tggaatggcc 1681 ggcaatccag agggtcacgc tgcattatta agaccggggg aactggttgc tattacggcg 1741 tcggctctcc aggcgtttag agaggtcgct cggttggcgg aacccacaga cccgtgggcg 1801 gaaattacgc agggaccatc tgagtccttt gtggattttg ccaatcgtct tataaaggcg 1861 gttgaagggt cagatctccc accttccgcg cgggctccgg tgatcattga ctgctttagg 1921 cagaagtcac agccagatat ccagcagctt atacgggcag caccctccac gctgaccacc 1981 ccaggagaga taatcaaata tgtgctagac aggcagaaga ctgcccctct tacggatcga 2041 ggcatagccg cggccatgtc gtctgctatt cagcccttag ttatggcagt agtcaataga 2101 gagagggatg gacaaactgg gtcgggtggt cgtgcccgag ggctctgcta cacttgtgga 2161 tccccgggac attatcaggc gcagtgcccg aaaaaacgaa agtcaggaaa cagccgtgag 2221 cgatgtcagt tgtgtgacgg gatgggacac aacgctaaac agtgcagaag gcgggatggc 2281 aaccagggcc aacgcccagg aagaggcctc tcttcggggc cgtggcccgt ctctcagcgg 2341 cctgctgtct cgttagcgat gacaatggaa cataaagatc gccccttggt tagggtcatt 2401 ctgactaaca ctgggagtca tccggtcaaa cagcgttcgg tgtatatcac cgcgctgttg 2461 gactctggag cggacatcac tattatttca gaggaggatt ggcccaccga ttggccagtg 2521 atggaggccg cgaacccgca gatccatggg ataggagggg gaattcccat gcgaaaatcc 2581 cgggatatga tagaggtggg ggttattaac cgagacgggt ctttggagcg acccctgctc 2641 ctcttccccg cagtagctat ggttagaggg agtatcctag gaagagattg tctgcagggc 2701 ctagggctcc gcttgacaaa tttataggga gggccactgt tcttactgtt gcgctacatc 2761 tggctattcc gctcaaatgg aagccagacc acacgcctgt gtggattgac cagtggcccc 2821 ttcctgaagg taaacttgta gcgctaacgc aattagtgga aaaagaatta cagttaggac 2881 atatagaacc ttcacttagt tgttggaaca cacctgtctt tgtgatccgg aaggcttccg 2941 ggtcttatcg cttattgcat gacttgcgcg ctgttaacgc caagcttgtt ccttttgggg 3001 ccgtccaaca gggggcgcca gttctctccg cgctcccgcg tggctggccc ctgatggtcc 3061 tagacctcaa ggattgcttc ttttctattc ctcttgcgga acaagatcgc gaagcttttg 3121 catttacgct cccctctgtg aataaccagg cccccgctcg aagattccaa tggaaggtct 3181 tgccccaagg gatgacctgt tctcccacta tctgtcagtt ggtggtgggt caggtacttg 3241 agcccttgcg actcaagcac ccatctctgc gcatgttgca ttatatggat gatcttttgc 3301 tagccgcctc aagtcatgat gggttggaag cggcagggga ggaggttatc agtacattgg 3361 aaagagccgg gttcaccatt tcgcctgata agatccagag ggagcccgga gtacaatatc 3421 ttgggtacaa gttaggcagt acgtatgtag cacccgtagg cttggtagca gaacccagga 3481 tagccacctt gtgggatgtt caaaagctgg tggggtcact tcagtggctt cgcccagcgt 3541 taggaatccc gccacgactg atgggcccct tttatgagca gttacgaggg tcagatccta 3601 acgaggcgag ggaatggaat ctagacatga aaatggcctg gagagagatc gtacagctca 3661 gcaccactgc tgccttggaa cgatgggacc ctgccctgcc tctggaagga gcggtcgcta 3721 gatgtgaaca gggggcaata ggggtcctgg gacagggact gtccacacac ccaaggccat 3781 gtttgtggtt attctccacc caacccacca aggcgtttac tgcttggtta gaagtgctca 3841 cccttttgat tactaagcta cgcgcttcgg cagtgcgaac ctttggcaag gaggttgatg 3901 tcctcctgtt gcctgcatgc tttcgggagg accttccgct cccggagggg atcctgttag 3961 cccttagggg gtttgcagga aaaatcagga gtagtgacac gccatctatt tttgacattg 4021 cgcgtccact gcatgtttct ctgaaagtga gggttaccga ccaccctgta ccgggaccca 4081 ctgtctttac cgacgcctcc tcaagcaccc ataagggggt ggtagtctgg agggagggcc 4141 caaggtggga gataaaagaa atagctgatt tgggggcaag tgtacaacaa ctggaagcac 4201 gcgctgtggc catggcactt ctgctgtggc cgacaacgcc cactaatgta gtgactgact 4261 ccgcgtttgt cgcgaaaatg ttactcaaga tgggacagga gggagtcccg tctacagcgg 4321 cggcttttat tttagaggat gcgttaagcc aaaggtcagc catggccgcc gttctccacg 4381 tgcggagtca ttctgaagtg ccagggtttt tcacagaagg aaatgacgtg gcagatagcc 4441 aagccacctt tcaagcgtat cccttgagag aggctaaaga tcttcatact gctctccata 4501 ttggaccccg cgcgctatcc aaagcgtgta atatatctat gcagcaggct agggaggttg 4561 ttcagacctg cccgcattgt aattcagccc ctgcgttgga ggccggggta aaccctaggg 4621 gtttgggacc cctacagata tggcagacag actttacgct tgagcctaga atggcccccc 4681 gttcctggct cgctgttact gtggctaccg cctcgtcggc gatagtcgta actcagcatg 4741 gccgtgtcac atcggttgct gcgcgacatc attgggccac ggctatcgcc gttttgggaa 4801 gaccaaaggc cataaaaaca gataacgggt cttgcttcac gtctaaatcc acgcgagagt 4861 ggctcgcgag atgggggata gcacacacca ccgggattcc gggtaattcc cagggtcaag 4921 ctatggtaga gcgggccaac cggctcctga aggataagat ccgtgtgctt gcggaggggg 4981 acggttttat gaaaagaatc cccaccggca aacaggggga actactagcc aaggcaatgt 5041 atgccctcaa tcactttgag cgtggtgaga acacaaaaac accgatacaa aaacactgga 5101 gacctaccgt tcttacagaa ggacccccgg ttaaaatacg aatagagaca ggggagtggg 5161 aaaaaggatg gaacgtgcta gtctggggac gaggttatgc cgctgtgaaa aacagggaca 5221 ctgataagat tatttgggta ccctctcgaa aagttaaacc ggacatcacc caaaaggatg 5281 agttgactaa gaaggatgag gcgagccctc tctttgcagg catttctgac tgggcaccct 5341 ggaaaggtga gcaagaagga ctctaagaag aagccgccag caacaagcaa gaaagacccg 5401 gagaaggcac ccttgctgcc gtcgagaggt tatttcttct ttcaaatgat acttgtgtgc 5461 gtggttatta tttctgttgt cccaggggtg gggggagttc atctgttgca acaaccagga 5521 aacgtgtggg tcacctgggc aaataagacg ggccaaacag atttttgcct tagtctacag 5581 tcagcgacct cgccattccg cacctgcttg ataggcattc cacagtatcc tctgagcgcc 5641 cttaagggat atgtcactaa tgttactgct tgcgataacg atgccgattt agccagccaa 5701 acagcatgct tgatacaggc tctaaataca accctccctt gggaccccca agaattggat 5761 attttagggt cccagatgat taagaacgga acaaaccgta cgtgtgttac ctttggttcg 5821 gtgtgctata aagagaacaa tggcagtaca gtctgccaca tttttgatgg gaattttaat 5881 ggcactggct ggcggcgtca ccactttcgt ggctctctac gactacgagt cccggactga 5941 aacggacttg tccttcaaga aaggagaacg cctgcagatt gtcaacaaca cggaaggtga 6001 ctggtggctg gctcattccc tcactacagg acagacgggc tacatcccca gtaactatgt 6061 cgcgccctca gactccatcc aggctgaaga gtggtacttt gggaagatca ctcgtcggga 6121 gtccgagcgg ctgctgctca accccgaaaa cccccgggga accttcttgg tccgggagag 6181 cgagacgaca aaaggtgcct attgcctctc cgtttctgac tttgacaacg ccaaggggct 6241 caatgtgaag cactacaaga tccgcaagct ggacagcggc ggcttctaca tcacctcacg 6301 cacacagttc agcagcctgc agcagctggt ggcctactac tccaaacacg ctgatggctt 6361 gtgccaccgc ctgaccaacg tctgccccac gtccaagccc cagacccagg gactcgccaa 6421 ggacgcgtgg gaaatccccc gggagtcgct gcggctgggg gtgaagctgg ggcagggctg 6481 ctttggagag gtctggatgg ggacctggaa cggcaccacc agagtggcca taaagactct 6541 gaagcccggc accatgtccc cggaggcctt cctgcaggaa gcccaagtga tgaagaagct 6601 ccggcatgag aagctggttc agctgtacgc agtggtgtcg gaagagccca tctacatcgt 6661 cactgagtac atgagcaagg ggagcctcct ggacttcctg aagggagaga tgggcaagta 6721 cctgcggctg ccacagctcg tcgatatggc tgctcagatt gcatccggca tggcctatgt 6781 ggagaggatg aactacgtgc accgagacct gcgggcggcc aacatcctgg tgggggagaa 6841 cctggtgtgc aaggtggctg actttgggct ggcacgcctc atcgaggaca acgagtacac 6901 agcacggcaa ggtgccaagt tccccatcaa gtggacagcc cccgaggcgg ccctctatgg 6961 ccggttcacc atcaagtcgg atgtctggtc cttcggcatc ctgctgactg agctgaccac 7021 caagggccgg gtgccatacc cagggatggt caacagggag gtgctggacc aggtggagag 7081 gggctaccgc atgccctgcc cgcccgagtg ccccgagtcg ctgcatgacc tcatgtgcca 7141 gtgctggcgg aaggaccctg aggagcggcc cacttttgag tacctgcagg ccttcctgga 7201 ggactacttc acctcgacag agccccagta gacagcccgg atatttgcct ctttctttgc 7261 tcctggtgta gctgcagcac aggccttaag ggagattgaa cgcttggcat gttggtcggt 7321 taagcaagca aatttaacat cattagtatt gaatgcgatg ctggaggacg tgaacagcat 7381 ccggcacgcg gtgttgcaga atcgagcagc catcgatttc ttactcctgg cgcagggaca 7441 cgggtgtcaa gacgtagaag ggatgtgttg cttcaatctc agcgatcaca gtgagtccgt 7501 tcacaagacg ctccaagcca tgaaggaaca tacagagaag atacgggtgg aagacgatcc 7561 cataggggat tggtttacgc gcacgtttgg tagttttgga gggtggctcg cgaaaggtgt 7621 taagacgcta ctgtttgcat tgcttgtcat agtctgtcta ttagctatca ttccatgtat 7681 aatcaagtgc ttccaggact gtctatcgag aacaatgtat cagttcgtgg atgaacgcat 7741 aagatatcat agaattaggg agcaactgta ggttccgaac gcgatgtgac gggaggctgc 7801 gagggatatt cgggggaata ggagaatgcg aatcgggctg taacggggca aggcttgact 7861 gaggggacta taacatgtat aggcgctgag cggggcttcg gttgtacgcg gataggaatc 7921 ccctcaggac aattctgctt gaaatgtgat ggcaccttcc tgttttgccc ttagactatt 7981 caagttgcct ctgtggatta ggactggaga cagctcggat ggtctgatgg ccaaatagag 8041 caagctagat aagtagctgc gaaatacgct tttgcatagg gagggggaaa tgtagtctta 8101 tgcaatactc ttatgtaacg atgaaacagc aatatgcctt ataaggagaa agaaggcact 8161 gtacacgttg attggtggaa gtaaggtggt atggtcatgg tgtgatcgtg ccttattagg 8221 aagacaacag acgggtcaga catggattgg acgatcccct tagttccgcg ttgcagagag 8281 attgtattta agtgcctagc ttgatacaat aaacgccatt ttacctccca ccacattggt 8341 gtgcacctgg gtagatggac agaccgttga gtccctaacg attgcgaaca cctgaatgaa 8401 gctgaaggct tcatt //